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Baicalein, a flavonoid extracted from the roots of Scutellaria baicalensis Georgi., has various pharmacological effects due to its high antioxidant activity. However, no study yet been conducted on protective efficacy baicalein against oxidative stress in Schwann cells. In this study, we evaluated effect DNA damage and apoptosis induced by hydrogen peroxide (H2O2) HEI193 For purpose, cells exposed H2O2 presence or absence were applied cell viability assay, immunoblotting, Nrf2-specific small...

Radix platycodi is the root of Platycodon grandiflorus A. DC, which has been widely used as a food material and for treatment number chronic inflammatory diseases in traditional oriental medicine. In this study, anti‑inflammatory effects saponins isolated from radix (PGS) on production mediators cytokines lipopolysaccharide (LPS)-stimulated BV2 murine microglial cells were examined. We also investigated PGS LPS‑induced nuclear factor‑κB (NF-κB) activation phosphoinositide 3-kinase (PI3K)/AKT...

Ganoderma lucidum, a well-known medicinal mushroom, is highly valued and commonly used in Oriental medicine. Although recent experimental data has revealed the proapoptotic potency of G. lucidum extracts, underlying mechanisms this apoptotic activity have not yet been studied detail. In present study, effects ethanol extracts (EGL) on growth an AGS human gastric carcinoma cell line were investigated. We found that EGL treatment resulted dose time-dependent significant decrease viability...

Ganoderma lucidum is a traditional Oriental medicine that has been widely used as tonic to promote longevity and health in Korea other Asian countries. Although great deal of work carried out on the therapeutic potential this mushroom, pharmacological mechanisms its anti-inflammatory actions remain unclear. In study, we evaluated inhibitory effects G. ethanol extract (EGL) production inflammatory mediators cytokines lipopolysaccharide (LPS)-stimulated murine BV2 microglia. We also...

Ginseng, the root of Panax ginseng C.A. Meyer (Araliaceae), is a widely known traditional medicine that has been utilized throughout Asia for several thousand years. Ginseng saponins exert various important pharmacological effects regarding control number diseases. The aim present study was to identify anti‑inflammatory total extracted from (TSG) on lipopolysaccharide (LPS)‑stimulated mouse RAW 264.7 macrophages. inhibitory TSG LPS‑induced nitric oxide (NO) production and tumor necrosis...

The mushroom Ganoderma lucidum has been widely used as a traditional herbal medicine for many years. Although several studies have focused on the anti-oxidative activity of this mushroom, molecular mechanisms underlying its not yet clearly established. present study investigated cytoprotective effect ethanol extract (EGL) against oxidative stress (hydrogen peroxide, H2O2) and elucidated in C2C12 myoblast cell line.Oxidative markers were determined by using comet assay to measure reactive...

Objectives:The stomach is a sensitive digestive organ that susceptible to exogenous pathogens from the diet.In response such pathogens, induces oxidative stress, which might be related development of both gastric organic disorders as gastritis, ulcers, and cancer, functional dyspepsia.This study was accomplished investigate effect Ganoderma lucidum pharmacopuncture (GLP) on chronic ulcers in rats. Methods:The rats were divided into 4 groups 8 animals each: normal, control, normal saline (NP)...

Alcohol abuse is a public issue and one of the major causes liver disease worldwide. This study was aimed at investigating protective effect Ganoderma lucidum pharmacopuncture (GLP) against hepatotoxicity induced by acute ethanol (EtOH) intoxication in rats.Sprague-Dawley (SD) rats were divided into 4 groups 8 animals each: normal, control, normal saline (NP) GLP groups. The NP received orally. treated daily with injections extract, respectively. control group no treatment. all groups,...

The purpose of this study was to find out validity Surface Electromyography(sEMG) compared with Nerve Conduction Study and clinical assessment scale as factors for facial palsy.We investigated 50 cases patients peripheral palsy who had records sEMG NCS check. Then we analyzed the correlation between that carried around 1 week after onset. And scales were measured three times week, 3-4 weeks 5-6 Clinical used in House-brackmann grade, Yanagihara unweighted grading Sunnybrook system. We...

The purpose of this study is to compare the effects bee venom pharmacopuncture (BVP) therapy according methods used treat knee osteoarthritis (OA): intra-acupoint combined with intra-articular injection, and injection.A total 69 patients were recruited by Department Acupuncture & Moxibustion at Dong- Eui Oriental University Hospital from February 1 July 23, 2012. assigned 3 groups: first group intraarticular BVP Injection (the experimental group), 2nd injection (control groupⅠ), 3rd groupⅡ)....

Objectives: The purpose of this study is to investigate the effect cervical acupotomy & acupunture on facial&trigemial nerve branch for peripheral facial paralysis and postauricular pain. Methods: We investigated 30 patients with who had visited at Department Acupuncture Moxibustion Medicine Korean Hospital Dong-Eui University from April 1st, 2013 30th, 2014. Group A was treated by acupuncture pharmacopuncture Cervical group B routine point without acupotomy. Results: improvement...

This study investigated the effect of ethanol extracts Ganoderma lucidum (EGL) on correlation between tightening tight junctions (TJs) and anti-invasive activity in human gastric adenocarcinoma AGS cells to elucidate further possible anticancer mechanisms that G exerts. Within concentrations EGL were not cytotoxic, markedly inhibited cell motility invasiveness a concentration-dependent manner. The activities matrix metalloproteinases (MMP)-2 MMP-9 dose-dependently by treatment with EGL, this...

The gastric ulcer is a common disorder of the stomach and duodenum. basic physiopathology results from an imbalance between some endogenous aggressive cytoprotective factors. This study examined whether Ganoderma lucidum pharmacopuncture (GLP) would provide protection against acute ulcers in rats.Sprague-Dawley rats were divided randomly into 4 groups 8 each: normal, control, normal saline (NP) GLP groups. experimental was induced by using EtOH/HCl solution group received same amount instead...

Eun Ju Lee, Tae Kyung Kim, Chang Min Shin, Jong Cheol Seo, Seo Whi Si Yong Cho, Hyun Yoon, Hong Kim. Journal of Acupuncture Research 2024;41:69-73. https://doi.org/10.13045/jar.2023.00346

Objectives: This study aimed to analyze the results and review outcomes satisfaction levels of 2023 Busan Korean medicine infertility treatment support project.Methods: A total 137 female 26 male participated in project, which encompassed herbal pharmacopuncture over 4-month period. Data pertaining patients' general, demographic, fertility-related characteristics were collected before initiation. During treatment, information regarding treatments administered by medical doctors was recorded,...

Rehmannia glutinosa pharmacopuncture solution (RGPS) was investigated to determine both its anti-allergic inflammatory effects on mast cells and detailed mechanism of actions.We whether RGPS suppress cytokines, enzymes, FcεRI expression FcεRImediated signaling in RBL-2H3 stimulated with anti-DNP IgE/DNP-HSA. The suppressive the levels cytokines such as IL-1β, IL-6 GM-CSF were measured using emzyme-linked immunospecific assay (ELISA). mRNA enzymes (HDC2, COX-1, COX-2 5LO) αβγsubunits reverse...

Objectives : The aim of this study is to determine whether Chinemys reevesii Gray pharmacopuncture a clinically effective treatment for women with knee osteoarthritis. Methods Female patients osteoarthritis were recruited from May 1, 2014 April 15, 2015 at the Department Acupuncture & Moxibustion Medicine Dong-Eui University Korean Medical Hospital. Patients randomly assigned two groups. 4.0 ml was injected acupuncture points experimental group(n = 24) twice week three weeks. control...