A5009984334- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
- Lung Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- Ultrasound in Clinical Applications
- Trauma Management and Diagnosis
- Lymphatic System and Diseases
- Lymphatic Disorders and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Pneumonia and Respiratory Infections
- Advances in Oncology and Radiotherapy
- Streptococcal Infections and Treatments
- COVID-19 and healthcare impacts
- Radiology practices and education
- Palliative Care and End-of-Life Issues
- Antibiotic Use and Resistance
- Myasthenia Gravis and Thymoma
- Hip and Femur Fractures
- Dental Research and COVID-19
- Global Cancer Incidence and Screening
- Social Media in Health Education
- Multiple and Secondary Primary Cancers
Guy's and St Thomas' NHS Foundation Trust
2015-2023
Western Sydney University
2023
King's College Hospital
2020
St Thomas' Hospital
2015-2020
King's College School
2019
King's College London
2016-2019
Thomas Foundation
2018
Asthma Association
2017
Government Medical College
2016
St. Thomas Hospital
2016
BackgroundPrimary spontaneous pneumothorax occurs in otherwise healthy young patients. Optimal management is not defined and often results prolonged hospitalisation. Data on efficacy of ambulatory options are poor. We aimed to describe the duration hospitalisation safety compared with standard care.MethodsIn this open-label, randomised controlled trial, adults (aged 16–55 years) symptomatic primary were recruited from 24 UK hospitals during a period 3 years. Patients randomly assigned (1:1)...
Background The principal aim of malignant pleural effusion (MPE) management is to improve health-related quality life (HRQoL) and symptoms. Methods In this open-label randomised controlled trial, patients with symptomatic MPE were randomly assigned either indwelling catheter (IPC) insertion the option talc pleurodesis or chest drain pleurodesis. primary end-point was global health status, measured 30-item European Organisation for Research Treatment Cancer Quality Life Core Questionnaire...
Introduction The development of malignant pleural effusion (MPE) results in disabling breathlessness, pain and reduced physical capability with treatment a palliative strategy. Ambulatory management MPE has the potential to improve quality life (QoL). OPTIMUM trial is designed determine whether full outpatient an indwelling catheter (IPC) pleurodesis improves QoL compared traditional inpatient care chest drain talc pleurodesis. currently open for any centres interested collaborating this...
Pleural fluid adenosine deaminase (pfADA) is not routinely measured in patients with undiagnosed pleural effusion due to limited evidence of its diagnostic utility areas low tuberculosis (TB) prevalence.We conducted a retrospective consecutive case series analysis all who underwent pfADA testing from 2009 2015 at tertiary service centre south London. Using receiver operating characteristic (ROC) curve analysis, we identified the optimal threshold which maximal sensitivity and specificity...
Indwelling pleural catheters (IPC) are increasingly becoming a first-line treatment in the management of malignant effusions. Ambulatory using IPC used this patient group whilst they receiving concurrent chemotherapy. There currently no prospective trials examining safety This study's objective is to determine if insertion safe patients undergoing chemotherapy.We conducted retrospective analysis all who underwent for effusion at our trust from September 2010 December 2014. Data was collected...
Abstract Introduction Malignant pleural effusions (MPEs) are common. MPE causes significant breathlessness and impairs quality of life. Indwelling catheters (IPC) allow ambulatory drainage reduce hospital days re-intervention rates when compared to standard talc slurry pleurodesis. Daily accelerates pleurodesis, instillation via the IPC has been proven feasible safe. Surgical pleurodesis video-assisted thoracoscopic surgery (VATS) is considered a one-off intervention for often recommended...
The key guidelines in the management of primary spontaneous pneumothorax (PSP) include 2010 British Thoracic Society (BTS) Pleural Disease guideline and 2001 American College Chest Physicians (ACCP) Consensus Statement. Current recommendations are dependent on radiographic measures which differ between these two guidelines. aim this study is to compare size classification PSP cases, according BTS ACCP guidelines, evaluate compliance. We conducted a retrospective evaluation all episodes...
<h3>ABSTRACT</h3> Achieving competence in thoracic ultrasound is a mandatory requirement for the successful completion of respiratory specialty training UK. We evaluated trainee competencies, access to and confidence by means nationally distributed survey with participation 202 (of approximately 600) trainees. 65.8% (131/199) responders are RCR Level 1 accredited 20.6% (22/107) these trainees had performed fewer than 20 ultrasounds past year. 29.2% (50/171) reported that an ultrasonographer...
In today’s quandary, the effort required to prevent disease occurrence should be more as compared methodologies followed for identifying it. this paper list down different number of diseases are affected in distinct regions extracted and by fixing based coupling cohesion range metric severity level each its dependence will confirmed. By preparing metrics, additional tests performed measure updating value is ‘1’ then very high otherwise consider low.
In early March 2020, a 53-year-old man was admitted to King’s College Hospital (KCH). He presented with 2-week history of dry cough, followed by fevers. had long flight 9 weeks prior admission. His presentation the emergency department prompted feeling increasingly breathless; his cough occasionally productive yellow sputum streaks haemoptysis. no medical history. temperature 38°C peripheral oxygen saturation level 92% on room air, respiratory rate 28 breaths per minute but he...
CTD-related pleural effusions are rare and challenging to diagnose. Our lung inflammation service (with expertise in rheumatology, interstitial disease respiratory failure) works closely with the team. This study aims review multidisciplinary approach at a tertiary centre. All patients St Thomas’ Hospital, London were included. Retrospective data collected from Dec 2013 2016. The performed an expert clinical assessment targeted investigations. 11 (ages 23–77) identified CTD related disease....
Abstract Background Malignant pleural effusion (MPE) is a common, serious problem predominantly seen in metastatic lung and breast cancer malignant mesothelioma. Recurrence of symptoms significantly impair people’s daily lives. Numerous treatment options exist, yet choosing the most suitable depends on many factors making decisions can be challenging pressured, time-sensitive clinical environments. Clinicians identified need to develop decision support tool. This paper reports process...
<b>Background:</b> Our group first described the use of oral midodrine, an alpha-1 adrenergic agonist as a novel therapy for idiopathic recurrent treatment-refractory chylothorax. <b>Objective:</b> To describe our subsequent experience midodrine in chylothorax <b>Methods:</b> We conducted retrospective review all patients commenced on between 2015 and 2020 centre. <b>Results:</b> identified three who were treated with midodrine. The table below summarises results. <b>Measurements Main...
<b>There was a significant reduction in pleural infection incidence, by almost third, the year following start of #COVID19 pandemic. Public health measures enforced during this period are likely to have played role.</b>https://bit.ly/3QAPPR9
<h3>Background</h3> While indwelling pleural catheter (IPC) is widely accepted as a primary treatment option for managing malignant effusions (MPEs), there limited research on the psychological and social impact of living with an IPC. <h3>Aims</h3> To investigate psychosocial IPC among patients MPEs. <h3>Methods</h3> A qualitative study was performed involving adult MPEs managed IPCs between May 2022 2023 at single tertiary centre. Semi-structured interviews were conducted participants two...
We describe a case of 38-year-old, HIV-positive asthmatic man with history intravenous methamphetamine substance misuse who presented worsening dyspnoea, wheeze, productive cough without haemoptysis and deteriorating exercise tolerance. His chest X-ray was clear subsequent CT scanning demonstrated multilobar, patchy consolidation ground glass change in the lung parenchyma. CD4 count 864 cells/mm 3 (n=500–1500 ) viral load 863 IU/mL. Our primary diagnosis an atypical pneumonia associated...
<h3>Introduction</h3> Malignant pleural effusion (MPE) management has dramatically changed in the last decade with increasing use of indwelling catheters (IPC) and thoracoscopy. Although treatment is aimed at improving health related quality life (HRQOL), data on outcomes are limited, guided by clinician perspectives experiences. <h3>Aims</h3> We sought HRQOL for patients MPE its impact decision making worldwide. present UK data. <h3>Methods</h3> invited all respiratory doctors to complete...