A5083237255- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Pneumothorax, Barotrauma, Emphysema
- Trauma Management and Diagnosis
- Radiology practices and education
- Occupational and environmental lung diseases
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lymphatic Disorders and Treatments
- Airway Management and Intubation Techniques
- SARS-CoV-2 and COVID-19 Research
- Streptococcal Infections and Treatments
- Advances in Oncology and Radiotherapy
- Lymphatic System and Diseases
- COVID-19 Clinical Research Studies
- Biomedical and Engineering Education
- Long-Term Effects of COVID-19
- Myasthenia Gravis and Thymoma
- Radiation Dose and Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Polyomavirus and related diseases
- Infectious Diseases and Tuberculosis
- Health and Well-being Studies
King Faisal Specialist Hospital & Research Centre
2021-2025
Guy's and St Thomas' NHS Foundation Trust
2013-2023
Islamic University of Madinah
2023
St Thomas' Hospital
2012-2021
Churchill Hospital
2020
King's College School
2016-2018
Thomas Foundation
2015-2018
Whittington Hospital
2017
University College London
2017
St. Thomas Hospital
2016
Malignant pleural effusion affects more than 750,000 persons each year across Europe and the United States. Pleurodesis with administration of talc in hospitalized patients is most common treatment, but indwelling catheters placed for drainage offer an ambulatory alternative. We examined whether administered through catheter was effective at inducing pleurodesis use alone.Over a period 4 years, we recruited malignant 18 centers Kingdom. After insertion catheter, underwent regularly on...
Malignant pleural effusion (MPE) is challenging to manage. Talc pleurodesis a common and effective treatment. There are no reliable data, however, regarding the optimal method for talc delivery, leading differences in practice recommendations.To test hypothesis that administration of poudrage during thoracoscopy with local anesthesia more than slurry delivered via chest tube successfully inducing pleurodesis.Open-label, randomized clinical trial conducted at 17 UK hospitals. A total 330...
Abstract Objectives The purpose of this study is to provide expert consensus recommendations establish a global ultrasound curriculum for undergraduate medical students. Methods 64 multi-disciplinary experts from 16 countries, 50 consultants, and 21 students residents contributed these recommendations. A modified Delphi method was used that included systematic literature search, evaluation the quality by GRADE system, RAND appropriateness panel judgment decisions. process four in-person...
Intrapleural tissue plasminogen activator/deoxyribonuclease (tPA/DNase) therapy is increasingly used in pleural infection. Bleeding risks and costs associated with tPA remain the clinical concerns. Our dose de-escalation series aims to establish lowest effective dosing regimen for tPA/DNase. This study assesses intrapleural use of 2.5 mg tPA/5 DNase infection.Consecutive patients infection treated a starting regime were included from two centres Australia UK. Escalation was permitted if...
Background The principal aim of malignant pleural effusion (MPE) management is to improve health-related quality life (HRQoL) and symptoms. Methods In this open-label randomised controlled trial, patients with symptomatic MPE were randomly assigned either indwelling catheter (IPC) insertion the option talc pleurodesis or chest drain pleurodesis. primary end-point was global health status, measured 30-item European Organisation for Research Treatment Cancer Quality Life Core Questionnaire...
ABSTRACT Background The role of fiberoptic bronchoscopy (FOB) in the management patients presenting with pulmonary infiltrates after hematopoietic stem cell transplant (HSCT) remains unclear. We aimed to evaluate diagnostic value and safety FOB at our center. Methods This retrospective study included all post‐HSCT who underwent between 2016 2019. demographic, clinical, interventional, microbiological, histological data changes 6‐month outcome were recorded. Results A total 86 consecutive...
Renal cell carcinoma (RCC) is the most common malignant tumor of kidney, with a rising global incidence. The epidemiology, clinical presentation, and management outcomes RCC vary across different regions, especially in low-resource settings. This study aims to analyze demographic patterns, characteristics, treatment modalities, patients at East Oncology Center (EOC) Sudan. A retrospective was conducted Center, Sudan, including all diagnosed between 2013 2024. Data were collected from...
Background: Lumbar disc degeneration (LDD) results from aging, mechanical stress, genetics, and lifestyle factors, causing dehydration, height loss, herniation. MRI helps assess these changes, which often correlate with disability indices like the Oswestry Disability Index (ODI). Understanding this link improves diagnosis treatment. This study explores relationship between findings scores for better patient care. Objective: Evaluation of lumber on in index. Methodology: cross-sectional...
<title>Abstract</title> <bold>Background</bold> Despite the significant mortality, data on end-of-life (EoL) discussions during COVID-19 pandemic are scarce. Health care providers had to cope with challenges, particularly overcoming barriers effective communication patients and their families, lack of information therapy prognosis. This study was undertaken assess satisfaction close family members (CFMs) EoL for hospitalized severe infection. <bold>Methods</bold> The conducted in five major...
Introduction The development of malignant pleural effusion (MPE) results in disabling breathlessness, pain and reduced physical capability with treatment a palliative strategy. Ambulatory management MPE has the potential to improve quality life (QoL). OPTIMUM trial is designed determine whether full outpatient an indwelling catheter (IPC) pleurodesis improves QoL compared traditional inpatient care chest drain talc pleurodesis. currently open for any centres interested collaborating this...
Physicians face considerable challenges in ensuring safe and effective care for patients admitted to hospital with pleural disease. While subspecialty development has driven up standards of care, this been tempered by the resulting loss procedural experience general medical teams tasked managing acute This review aims define a framework though which minimum standard might be implemented. written clinicians from across UK representing all types secondary hospital. Its content formed on basis...
Pleural fluid adenosine deaminase (pfADA) is not routinely measured in patients with undiagnosed pleural effusion due to limited evidence of its diagnostic utility areas low tuberculosis (TB) prevalence.We conducted a retrospective consecutive case series analysis all who underwent pfADA testing from 2009 2015 at tertiary service centre south London. Using receiver operating characteristic (ROC) curve analysis, we identified the optimal threshold which maximal sensitivity and specificity...
Indwelling pleural catheters (IPC) are increasingly becoming a first-line treatment in the management of malignant effusions. Ambulatory using IPC used this patient group whilst they receiving concurrent chemotherapy. There currently no prospective trials examining safety This study's objective is to determine if insertion safe patients undergoing chemotherapy.We conducted retrospective analysis all who underwent for effusion at our trust from September 2010 December 2014. Data was collected...
The key guidelines in the management of primary spontaneous pneumothorax (PSP) include 2010 British Thoracic Society (BTS) Pleural Disease guideline and 2001 American College Chest Physicians (ACCP) Consensus Statement. Current recommendations are dependent on radiographic measures which differ between these two guidelines. aim this study is to compare size classification PSP cases, according BTS ACCP guidelines, evaluate compliance. We conducted a retrospective evaluation all episodes...
<b><i>Background:</i></b> Indwelling pleural catheters (IPC) are increasingly used for management of recurrent (especially malignant) effusions. Pleural infection associated with IPC use remains a concern. Intrapleural therapy tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) significantly reduces surgical referrals in non-IPC infection, but data on its IPC-related scarce. <b><i>Objective:</i></b> To assess the safety efficacy...
<h3>ABSTRACT</h3> Achieving competence in thoracic ultrasound is a mandatory requirement for the successful completion of respiratory specialty training UK. We evaluated trainee competencies, access to and confidence by means nationally distributed survey with participation 202 (of approximately 600) trainees. 65.8% (131/199) responders are RCR Level 1 accredited 20.6% (22/107) these trainees had performed fewer than 20 ultrasounds past year. 29.2% (50/171) reported that an ultrasonographer...
CTD-related pleural effusions are rare and challenging to diagnose. Our lung inflammation service (with expertise in rheumatology, interstitial disease respiratory failure) works closely with the team. This study aims review multidisciplinary approach at a tertiary centre. All patients St Thomas’ Hospital, London were included. Retrospective data collected from Dec 2013 2016. The performed an expert clinical assessment targeted investigations. 11 (ages 23–77) identified CTD related disease....
Abstract Background Malignant pleural effusion (MPE) is a common, serious problem predominantly seen in metastatic lung and breast cancer malignant mesothelioma. Recurrence of symptoms significantly impair people’s daily lives. Numerous treatment options exist, yet choosing the most suitable depends on many factors making decisions can be challenging pressured, time-sensitive clinical environments. Clinicians identified need to develop decision support tool. This paper reports process...
Coronavirus disease 2019 (COVID-19)-associated mortality is predominantly due to respiratory failure. However, risk factors and predictive models for progression in patients with COVID-19 are not consistent across the globe. In this study, we aimed assess associated intensive care (ICU) admission pneumonia. Information was retrieved from database of all admitted pneumonia between March 2020 July at a tertiary center Saudi Arabia. The patients’ demographic, clinical, laboratory radiological...