Mark Slade

ORCID: 0000-0002-0388-3000
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Pleural and Pulmonary Diseases
  • Tracheal and airway disorders
  • Airway Management and Intubation Techniques
  • COVID-19 Clinical Research Studies
  • Ultrasound in Clinical Applications
  • Occupational and environmental lung diseases
  • Pneumothorax, Barotrauma, Emphysema
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Radiation Dose and Imaging
  • Esophageal and GI Pathology
  • Intensive Care Unit Cognitive Disorders
  • Head and Neck Cancer Studies
  • Lung Cancer Treatments and Mutations
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Respiratory Support and Mechanisms
  • Dysphagia Assessment and Management
  • Medical Imaging and Pathology Studies
  • Foreign Body Medical Cases
  • Trauma Management and Diagnosis
  • Coronary Artery Anomalies
  • SARS-CoV-2 detection and testing
  • Evaluation of Teaching Practices
  • Pneumonia and Respiratory Infections

Gloucestershire Hospitals NHS Foundation Trust
2015-2023

University Hospitals Birmingham NHS Foundation Trust
2021

Oxford University Clinical Research Unit Indonesia
2021

Public Health Scotland
2021

University of Dundee
2021

Medical Research Council
2021

NIHR Clinical Research Network
2021

National Institute for Health Research
2021

National Records of Scotland
2021

Intensive Care National Audit & Research Centre
2021

Section 3: Clinical features which predict the presence of mesothelioma Recommendations 4: Staging systems Recommendation 5: Imaging modalities for diagnosing and staging 6: Pathological diagnosis

10.1136/thoraxjnl-2017-211321 article EN Thorax 2018-02-14

| Diagnosis of mediastinal/hilar lymph nodes and peribronchial masses || Conventional transbronchial fine needle aspiration (TBNA) B √ Endobronchial ultrasound-guided (EBUS-TBNA) D Therapeutic procedures for malignant disease Malignant airway obstruction 1. debulking tumours 2. electrocautery or diathermy

10.1136/thoraxjnl-2011-200713 article EN Thorax 2011-10-10

Malignant pleural effusion (MPE) is challenging to manage. Talc pleurodesis a common and effective treatment. There are no reliable data, however, regarding the optimal method for talc delivery, leading differences in practice recommendations.To test hypothesis that administration of poudrage during thoracoscopy with local anesthesia more than slurry delivered via chest tube successfully inducing pleurodesis.Open-label, randomized clinical trial conducted at 17 UK hospitals. A total 330...

10.1001/jama.2019.19997 article EN JAMA 2019-12-05

This new guideline covers the rapidly advancing field of interventional bronchoscopy using flexible bronchoscopy. It includes use more complex diagnostic procedures such as endobronchial ultrasound, interventions for relief central airway obstruction due to malignancy and recent development therapies chronic obstructive pulmonary disease asthma. The aims help all those who undertake understand about this important area. also inform respiratory physicians other specialists dealing with lung...

10.1136/thoraxjnl-2011-201052 article EN Thorax 2011-10-14

Rationale: Assessing the early use of video-assisted thoracoscopic surgery (VATS) or intrapleural enzyme therapy (IET) in pleural infection requires a phase III randomized controlled trial (RCT). Objectives: To establish feasibility randomization versus non-surgery as well key outcome measures which are important to identify relevant patient-centered outcomes RCT. Methods: MIST-3 was prospective multicenter All-comers with confirmed diagnosis were enrolled and those ongoing sepsis after up...

10.1164/rccm.202305-0854oc article EN cc-by American Journal of Respiratory and Critical Care Medicine 2023-10-11

The full guideline for the investigation and management of malignant pleural mesothelioma is published in Thorax . following a summary recommendations good practice points. sections referred to refer guideline.

10.1136/bmjresp-2017-000266 article EN cc-by-nc BMJ Open Respiratory Research 2018-02-01

Data for 25261 patients with non-small cell lung cancer whose details were submitted to the National Lung Cancer Audit in England analysed assess effect of age at diagnosis on their clinical management, after accounting sex, stage, performance status and comorbidity. Multivariate logistic regression showed odds having histocytological confirmation anticancer treatment decreased progressively age, was also lower women. It is likely that these results have a multifactorial explanation, further...

10.1136/thoraxjnl-2011-200994 article EN Thorax 2012-07-06

Can the detection rate of flexible bronchoscopy for lung cancer be increased by a series simple quality improvement measures? Bronchoscopy-associated clinical parameters were prospectively recorded between 2001 and 2007 in patients with suspected malignancy. The bronchoscopy, diagnostic yield each biopsy modality possible impact different service-improvement measures assessed. 746 bronchoscopies performed 704 patients. malignancy was 83.6%, over time (67.3% (95% CI 52.9–79.7), 89.7%...

10.1183/09031936.00097110 article EN European Respiratory Journal 2010-08-06

A 75-year-woman with a Duke’s B adenocarcinoma of the caecum underwent staging CT examination which revealed an oval, 3.6×2.5 cm fluid attenuation mass (18 Hounsfield units) superior to carina, posterior trachea and medial oesophagus (figure 1). She had no symptoms relating mediastinal mass. Radiologically lesion was thought be most in keeping …

10.1136/bcr.07.2011.4447 article EN BMJ Case Reports 2012-03-27

<h3>Background</h3> The incidence of malignant pleural effusions (MPE) is increasing and overall prognosis remains poor. In-dwelling catheters (IPCs) relieve symptoms, but increase the risk infection. We reviewed survival times cases infection in patients with IPCs for MPE from 6 UK centres. <h3>Methods</h3> Baseline data were collected all IPC insertions 1/1/05 to 31/1/14. Survival analysed by underlying tumour. Results compared national data, a cohort 789 (the LENT cohort). scores used...

10.1136/thoraxjnl-2014-206260.123 article EN Thorax 2014-11-10

<h3>Background</h3> NICE lung cancer guidelines recommend choosing investigations that give the most information about diagnosis and staging with least risk to patient. In particular, performing CT scan before bronchoscopy, PET surgery avoiding tests only when on is also needed guide treatment. We report current UK practice for patients diagnosed following a GP referral assess impact of timing diagnostic number tests, times survival. <h3>Methods</h3> Data submitted National Lung Cancer Audit...

10.1136/thoraxjnl-2013-204457.152 article EN Thorax 2013-11-14
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