Mirjam-Colette Kempf

ORCID: 0000-0003-3796-4906
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Adolescent Sexual and Reproductive Health
  • HIV-related health complications and treatments
  • Cervical Cancer and HPV Research
  • HIV Research and Treatment
  • LGBTQ Health, Identity, and Policy
  • HIV/AIDS drug development and treatment
  • Food Security and Health in Diverse Populations
  • Reproductive tract infections research
  • Resilience and Mental Health
  • Homelessness and Social Issues
  • Cancer-related gene regulation
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Sex work and related issues
  • COVID-19 Impact on Reproduction
  • COVID-19 and Mental Health
  • Maternal Mental Health During Pregnancy and Postpartum
  • Health disparities and outcomes
  • Psychiatric care and mental health services
  • Viral-associated cancers and disorders
  • Public Health Policies and Education
  • Iron Metabolism and Disorders
  • Hemoglobinopathies and Related Disorders
  • Child and Adolescent Psychosocial and Emotional Development

University of Alabama at Birmingham
2016-2025

University of Miami
2021

Georgetown University
2021

University of North Carolina at Chapel Hill
2021

Johns Hopkins University
2021

University of Mississippi Medical Center
2021

Carl von Ossietzky Universität Oldenburg
2020

Pulmonary and Critical Care Associates
2005

Jüdisches Krankenhaus Berlin
2001

University of Würzburg
1999

Retention in HIV medical care has been recognized as critical for long-term favorable clinical outcomes among HIV-positive patients. However, relatively little is known about specific factors related to adherence women rural areas the United States, where epidemic rapidly growing minorities and women. The objective of current study was assess barriers facilitators clinic visit southeastern region States. Forty were recruited from four outpatient clinics providing services patients residing...

10.1089/apc.2010.0065 article EN AIDS Patient Care and STDs 2010-07-30

To determine whether persistent viral suppression alters cognitive trajectories among HIV-infected (HIV+) women on combination antiretroviral therapy (cART) by investigating performance longitudinally in uninfected (HIV-) and 3 groups of HIV+ women: those with consistent after continuous cART use (VS), without virologic despite (NVS), intermittent (Int NVS).Two hundred thirty-nine VS, 220 NVS, 172 Int 301 HIV- from the Women's Interagency HIV Study (WIHS) completed neuropsychological testing...

10.1212/wnl.0000000000004491 article EN Neurology 2017-09-14

Importance Despite aging-related comorbidities representing a growing threat to quality-of-life and mortality among persons with HIV (PWH), clinical guidance for comorbidity screening prevention is lacking. Understanding distribution severity by sex gender essential informing guidelines promoting healthy aging in adults HIV. Objective To assess the association of human immunodeficiency virus on burden US modern treatment era. Design, Setting, Participants This cross-sectional analysis...

10.1001/jamanetworkopen.2023.27584 article EN cc-by-nc-nd JAMA Network Open 2023-08-07

Characterizing the genetically diverse HIV sequences that persist in reservoir despite antiretroviral therapy (ART) is critical to cure efforts. Our observations confirm proviruses persisting blood on ART, which are largely defective, broadly reflect extent of within-host evolution pre-ART. Moreover, on-ART clonal expansion not appreciably accompanied by loss distinct proviral lineages. In fact, genetic composition remained stable all but one participant, whom, after 12 years dating around...

10.1128/jvi.01655-23 article EN cc-by Journal of Virology 2024-01-12

This study describes the ways in which poverty and other structural factors create a risk environment for sub-optimal engagement HIV care among low-income women living with Southern USA, contributing to existing health disparities. We conducted qualitative 2012, involving in-depth interviews 14 stakeholders (service providers representatives of community-based organisations) 7 focus-group discussions 46 (89% African American). A thematic approach context social ecological model guided data...

10.1080/13691058.2015.1110255 article EN Culture Health & Sexuality 2015-12-15

Among places where people living with HIV experience and anticipate HIV-related stigma, stigma in health care settings may be particularly harmful. Utilizing an exploratory sequential mixed methods approach, we conducted interviews (n = 76) questionnaires (N 460) older adult women enrolled the Women's Interagency Study Birmingham, AL; Jackson, MS; Atlanta, GA; San Francisco, CA. Interviews addressed facilitators barriers to treatment adherence, including stigma. Qualitative data were coded...

10.1089/apc.2018.0282 article EN AIDS Patient Care and STDs 2019-04-01

In 2022, cisgender women accounted for one in five HIV diagnoses the United States. Existing structural, social, and behavioral factors impede women's engagement with prevention strategies including Pre-Exposure Prophylaxis (PrEP) access, condom usage, uptake of testing. This study explores perspectives living (WLWH) about that may contribute to acquisition their advice who benefit from strategies. We conducted semistructured interviews 40 WLWH were diagnosed on or after January 1, 2000....

10.1089/apc.2025.0006 article EN AIDS Patient Care and STDs 2025-03-14

Reported reasons for change or discontinuation of antiretroviral therapy ([delta]ART) include adverse events, intolerability, and nonadherence. Little is known how [delta]ART differ by gender.In a retrospective cohort study, rates alterations in large University-based HIV clinic were evaluated. Logistic regression analyses used to evaluate the relationship between gender. Cox proportional hazard models investigate time [delta]ART.In total, 631 HIV-positive individuals analyzed. Women (n =...

10.1097/qai.0b013e3181b628be article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2009-10-21

Despite the wide availability of effective treatments for HIV disease, many HIV-infected individuals are not in care, and women, particularly those residing resource-poor areas, may have greater difficulty accessing care than men. The purpose this research was to explore perceived barriers experienced by women living Deep South region United States. Qualitative methods were used generate in-depth descriptions women's experiences care. Participants (N = 40) recruited from 4 community-based...

10.1016/j.jana.2010.03.003 article EN Journal of the Association of Nurses in AIDS Care 2010-04-29

Symptoms guide disease management, and patients frequently report HIV-related symptoms, but HIV symptom patterns reported by have not been described in the era of improved antiretroviral treatment. The objectives our study were to investigate prevalence burden symptoms people living with attending an outpatient clinic. prevalence, burden, bothersomeness routine clinic visits during 2011 assessed using 20-item Symptom Index. Principal component analysis was used identify clusters...

10.1016/j.jana.2015.11.009 article EN Journal of the Association of Nurses in AIDS Care 2015-11-30

Resilience is defined as the ability and process to transform adversity into opportunities for growth adaptation. may be especially important people living with HIV (PLWH), who are susceptible anxiety depressive disorders, which commonly linked risk behaviors (i.e., alcohol drug abuse), poor adherence medical regimens, increased of morbidity mortality, related stigma discrimination. To date, few studies have examined impact resilience on health-related outcomes among PLWH, particularly...

10.1089/apc.2019.0309 article EN AIDS Patient Care and STDs 2020-08-01

Among people living with HIV (PLWH), HIV-related stigma predicts nonadherence to antiretroviral therapy (ART); however, the role of associated drug use is largely unknown. We examined association between substance (SU) and optimal ART adherence in a sample 172 self-reported HIV-infected users. Participants completed surveys on SU, stigma, adherence. The three classes greatest number participants exhibiting moderate/high-risk scores were for cocaine/crack cocaine (66.28%), cannabis (64.53%),...

10.1089/apc.2018.0311 article EN AIDS Patient Care and STDs 2019-06-01

An estimated 250 million people worldwide suffer from knee osteoarthritis (KOA), with older adults having greater risk. Like other age-related diseases, residents of high-deprivation neighborhoods experience worse KOA pain outcomes compared to their more affluent neighbors. The purpose this study was examine the relationship between neighborhood deprivation and severity in influence epigenetic age acceleration (EpAA) on that relationship. sample 128 participants mostly female (60.9%),...

10.1016/j.socscimed.2023.116088 article EN cc-by-nc-nd Social Science & Medicine 2023-07-10

Background: One mechanism through which social stigma of HIV affects health outcomes for people living with (PLWH) is internalization stigma. However, this transformation in the community into internalized may not be same magnitude all PLWH. We examined moderating effects 3 personality traits—fear negative evaluation, attachment-related anxiety, and dispositional resilience—in transforming perceived Furthermore, we investigated downstream these moderated associations on depressive symptoms...

10.1097/qai.0000000000001915 article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2018-12-07

To examine whether experienced poverty stigma is associated with worse HIV care and treatment outcomes.We analyzed cross-sectional data from 433 women living enrolled in the Women's Adherence Visit Engagement substudy of Interagency Study.Exposure was stigma, measured using Perceived Stigma Poverty Scale. Outcomes were viral suppression, CD4 cell count at least 350 cells/μl, attending all visits past 6 months. Multivariable logistic regression models adjusted for income, age, race/ethnicity,...

10.1097/qad.0000000000002189 article EN AIDS 2019-03-19

Objective African American (AA) women in the U.S. South experience significant HIV incidence, and efforts to support antiretroviral pre-exposure prophylaxis (PrEP) uptake maintenance among this group have been insufficient. This study aimed explore perceptions, attitudes, implementation preferences surrounding PrEP use for AA South.

10.1080/08870446.2024.2322079 article EN cc-by-nc-nd Psychology and Health 2024-03-05

Biased enrollment and attrition compromise the power of clinical trials limit generalizability findings. We identify predictors retention for HIV-discordant couples enrolled in prospective studies Zambia.A total 1995 discordant were invited to enroll. Predictors nonenrollment, loss follow-up, missed appointments evaluated using multivariate models. MF more likely be eligible enroll less lost follow-up than FM couples. Substantial losses occurred between testing (21.3% 28.1% FM) first visit...

10.1097/qai.0b013e31815d2f3f article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2008-01-01

Stigma in health care settings can have negative consequences on women living with HIV, such as increasing the likelihood of missed visits and reducing trust their clinical providers. Informed by prior stigma research considering knowledge gaps related to effect patient–provider race concordance, we conducted this study assess if concordance moderates expected association between HIV-related patients' Moderation analyses were using Women's Interagency HIV Study data (N = 931). We found...

10.1089/apc.2021.0096 article EN AIDS Patient Care and STDs 2021-11-01

African American women have disproportionately high prevalence rates of HIV and cervical cancer. HIV-infected are significantly less likely to obtain recommended cancer screenings than HIV-uninfected women. The purpose this study was examine sociocultural structural factors associated with screening among in Alabama. PEN-3 Model the Health Belief were used as theoretical frameworks. In-depth interviews conducted twenty identify perceptions, enablers, nurturers, perceived susceptibility,...

10.1089/apc.2014.0063 article EN AIDS Patient Care and STDs 2014-12-16

Ending the HIV epidemic requires that women living with (WLWH) have access to structurally competent HIV-related and other health care. WLWH may not regularly engage in care due inadequate quality; however, women's perspectives on quality of they receive are understudied. We conducted 12 focus groups three in-depth interviews Black (90%) Latina (11%) enrolled Women's Interagency Study Atlanta, GA, Birmingham, AL, Brooklyn, NY, Chapel Hill, NC, Chicago, IL, Jackson, MS from November 2017 May...

10.1186/s12939-020-01230-3 article EN cc-by International Journal for Equity in Health 2020-07-06
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