A5027157116- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Non-Invasive Vital Sign Monitoring
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Disease Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Failure Treatment and Management
- Advanced MRI Techniques and Applications
- Respiratory Support and Mechanisms
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Intensive Care Unit Cognitive Disorders
- Fuel Cells and Related Materials
- Sepsis Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- EEG and Brain-Computer Interfaces
- Methemoglobinemia and Tumor Lysis Syndrome
- COVID-19 Clinical Research Studies
Amsterdam University Medical Centers
2018-2023
University of Amsterdam
2012-2021
Amsterdam UMC Location University of Amsterdam
2013-2019
Netherlands Heart Institute
2018
University of Twente
2011-2012
Centre for Biomedical Engineering and Physics
2012
Background: Short-term mechanical circulatory support devices are increasingly used in cardiogenic shock after acute myocardial infarction. As no randomised evidence is available, the choice between high-output Impella or extra-corporeal membrane oxygenation (ECMO) still a matter of debate. Real-life data necessary to assess adverse outcomes and help guide treatment decision different devices. The purpose this study was compare characteristics clinical CP/5.0 with ECMO patients from Methods:...
Although transcutaneous bilirubinometers have existed for over 30 years, the clinical utility of technique is limited to a screening method hyperbilirubinemia, rather than replacement invasive blood sampling. In this study, we investigate reason value and address possibilities improvement.To obtain better insight into physiology bilirubin measurements, evaluated bilirubinometer that determines not only cutaneous concentration (TcB) but also volume fraction (BVF) in investigated skin volume....
Mortality in cardiogenic shock patients remains high. Short-term mechanical circulatory support with Impella can be used to the circulation these patients, but data from randomised controlled studies and 'real-world' are sparse. The aim is describe real-life on outcomes complications of our 12 years clinical experience after acute myocardial infarction identify predictors 6-month mortality.We a single-centre registry October 2004 December 2016 including all treated for infarction. We report...
Abstract Aims To assess differences in long-term outcome and functional status of patients with cardiogenic shock (CS) treated by percutaneous mechanical circulatory support (pMCS) intra-aortic balloon pump (IABP). Methods results Long-term follow-up the multicentre, randomized IMPRESS Severe Shock trial (NTR3450) was performed 5-year after initial randomization. Between 2012 2015, a total 48 severe CS from acute myocardial infarction (AMI) ST-segment elevation undergoing immediate...
The Evaluating Xience and left ventricular function in PCI on occlusiOns afteR STEMI (EXPLORE) trial did not show a significant benefit of percutaneous coronary intervention (PCI) the concurrent chronic total occlusion (CTO) ST-segment elevation myocardial infarction (STEMI) patients global (LV) systolic function. However possible treatment effect will be most pronounced CTO territory. Therefore, we aimed to study compared no-CTO recovery regional LV function, particularly Using...
The diagnosis of cardiogenic shock depends on clinical signs poor perfusion and low blood pressure. Lactate concentration will increase with tissue perfusion, it has prognostic value in patients. We sought to assess the lactate subjects admitted suspected ST-elevation myocardial infarction (STEMI).In 2,094 (93%) out 2,247 consecutive STEMI-subjects, was measured admission. 30-day mortality assessed addition peripheral hypoperfusion, systolic pressure (sBP), left ventricular ejection fraction...
Background In selected patients with an acute myocardial infarction (AMI) complicated by Cardiogenic shock (CS), mechanical circulatory support Impella may be beneficial, although conclusive evidence is still lacking. Nevertheless, it has been suggested that initiation prior to primary PCI might improve survival. Objective To investigate the effect pre-PCI versus immediate post-PCI on short term mortality. Methods A prospective, single center, observational study, was performed including all...
Objective Pulse (PPV) and systolic pressure variation (SPV) quantify variations in arterial related to heart-lung interactions have been introduced as biomarkers of preload dependency guide fluid treatment mechanically ventilated patients. However, respiratory intra-thoracic changes during spontaneous breathing are considered too small affect stroke volume sufficiently for the detection by PPV and/or SPV. This study addressed effects paced an external resistance on SPV detecting...
Global left ventricular (LV) function is routinely used to assess cardiac function; however, myocardial strain able identify more subtle dysfunction. We aimed determine the recovery and prognostic value of featuring tracking (FT) cardiovascular magnetic resonance (CMR) in ST-segment elevation infarction (STEMI) patients with a concurrent chronic total occlusion (CTO). In randomized EXPLORE trial, there was no significant difference global LV after percutaneous coronary intervention (PCI)...
Delirium is a severe complication in critical care patients. Accurate prediction could facilitate determination of which patients are at risk. In the past decade, several delirium models have been developed.To compare prognostic accuracy PRE-DELIRIC, E-PRE-DELIRIC, and Lanzhou models, to investigate difference PRE-DELIRIC model between receiving not mechanical ventilation.This retrospective study involved adult admitted intensive unit during 2-year period. was assessed by using Confusion...
Objective The impact on cardiac function of collaterals towards a concomitant chronic total coronary occlusion (CTO) in patients with ST-elevation myocardial infarction (STEMI) has not been investigated yet. Therefore, we have evaluated the well-developed compared poorly developed to CTO STEMI. Methods and results In EXPLORE trial, STEMI were randomised either percutaneous intervention (PCI) or no-CTO PCI. Collateral grades scored angiographically using Rentrop grade classification. Left...
For mechanically ventilated critically ill COVID-19 patients, prone positioning has quickly become an important treatment strategy, however, is labor intensive and comes with potential adverse effects. Therefore, identifying which intubated patients will benefit may help allocate resources. From the multi-center Dutch Data Warehouse of ICU from 25 hospitals, we selected all 3619 episodes in 1142 invasively patients. We excluded longer than 24 h. Berlin ARDS criteria were not formally...