A5103021694- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle physics theoretical and experimental studies
- Colorectal Cancer Surgical Treatments
- Synthesis and Properties of Aromatic Compounds
- Colorectal Cancer Screening and Detection
- Radioactive element chemistry and processing
- Minimally Invasive Surgical Techniques
- Drug Transport and Resistance Mechanisms
- Gastric Cancer Management and Outcomes
- Pharmacogenetics and Drug Metabolism
- Chemical Synthesis and Characterization
- Pelvic and Acetabular Injuries
- Diverticular Disease and Complications
- Enhanced Recovery After Surgery
- Tracheal and airway disorders
- Hernia repair and management
- Blood properties and coagulation
- Gastrointestinal disorders and treatments
- CAR-T cell therapy research
- Gastrointestinal Tumor Research and Treatment
- Appendicitis Diagnosis and Management
- Metabolism and Genetic Disorders
- Earthquake and Tsunami Effects
- Supramolecular Self-Assembly in Materials
Health Sciences University of Hokkaido
2017-2024
Japan Society of Laparoscopic Colorectal Surgery
2024
University of Tokyo Hospital
2024
Shuto General Hospital
2024
Yamaguchi University
2021-2023
Wakayama Medical University
2013-2023
St. Marianna University School of Medicine
2007-2022
Tokyo Medical and Dental University
2022
Nihon University
2004-2020
Jichi Medical University
2013-2019
We extend the Polyakov-loop extended Nambu--Jona-Lasinio model by introducing an effective four-quark vertex depending on Polyakov loop. The generates entanglement interactions between loop and chiral condensate. new is consistent with lattice QCD data at imaginary quark-number chemical potential real isospin potentials, particularly strong correlation deconfinement transitions also quark-mass dependence of order Roberge-Weiss endpoint. investigate influence location tricritical point...
CT angiography has gained widespread acceptance for preoperative evaluation of blood supply in patients with colorectal cancer. However, there have been few reports that pertain to the splenic flexure, which surgery is technically difficult. We used and colonography evaluate flexure.We defined flexure as junction distal third transverse colon proximal descending colon. reviewed 191 cases considered divided into two-thirds; we then determined part left colic artery (LCA) entered. also...
Although most bile acids (BAs) in feces are present noncovalent forms that can be extracted with ethanol, non-negligible amounts of saponifiable BAs also present. It is a major concern such routinely omitted from fecal BA measurements. We compared the profiles healthy stools were obtained with/without alkaline hydrolysis and found as much 29.7% (2.1-67.7%) total saponifiable. Specifically, treatment led to significant elevations isodeoxycholic acid (isoDCA) isolithocholic (isoLCA)...
Abstract Chimeric antigen receptor (CAR)‐T cell therapy has shown salient efficacy in cancer immunotherapy, particularly the treatment of B malignancies. However, CAR‐T for solid tumors remains inadequate. In this study, we displayed that c‐met is an appropriate therapeutic target papillary renal carcinoma (PRCC) using clinical samples, developed anti‐human cells, and investigated anti‐tumor cells orthotopic mouse model as pre‐clinical research. Administration anti‐c‐met induced marked...
Abstract Background While chimeric antigen receptor (CAR)‐T cell therapy has demonstrated excellent efficacy in hematopoietic malignancies, its clinical application solid cancers yet to be achieved. One of the reasons for such hurdle is a lack suitable CAR targets cancers. Methods GM2 one gangliosides, group glycosphingolipids with sialic acid glycan, and overexpressed various types In this study, by using interleukin (IL)‐7 chemokine (C‐C motif) ligand 19 (CCL19)‐producing human CAR‐T...
The phase structure of two-flavor QCD is explored for thermal systems with finite baryon- and isospin-chemical potentials, ${\ensuremath{\mu}}_{\mathrm{B}}$ ${\ensuremath{\mu}}_{\mathrm{iso}}$, by using the Polyakov-loop extended Nambu--Jona-Lasinio (PNJL) model. PNJL model scalar-type eight-quark interaction can reproduce lattice data at not only ${\ensuremath{\mu}}_{\mathrm{iso}}={\ensuremath{\mu}}_{\mathrm{B}}=0$, but also ${\ensuremath{\mu}}_{\mathrm{iso}}>0$...
We draw the three-flavor phase diagram as a function of light- and strange-quark masses for both zero imaginary quark-number chemical potential, using Polyakov-loop extended Nambu-Jona-Lasinio model with an effective four-quark vertex depending on Polyakov loop. The prediction is qualitatively consistent 2+1 flavor lattice QCD at potential degenerate potential.
Conversion to laparotomy is among the serious intraoperative complications and carries an increased risk of postoperative complications. In this cohort study, we investigated whether or not Endoscopic Surgical Skill Qualification System (ESSQS) affects conversion rate patients undergoing laparoscopic surgery for rectal cancer.
We investigate quark–gluon thermodynamics with the symmetry. The flavor-dependent twist boundary condition (TBC) is imposed on Nc degenerate flavor quarks in SU(Nc) gauge theory. This model useful to understand mechanism of color confinement. Thermodynamics this system studied by imposing TBC Polyakov-loop extended Nambu–Jona–Lasinio (PNJL) model. applied two- and three-color cases. symmetry preserved below some temperature Tc, but spontaneously broken above Tc. confinement Tc preserves...
We investigate the relation between confinement and symmetry in three-flavor QCD with imaginary isospin chemical potentials (μu, μd, μs) = (iθT, −iθT, 0), using Polyakov-loop extended Nambu–Jona–Lasinio (PNJL) model, where T is temperature. As for three-degenerate flavors, system has at θ 2π/3 hence Polyakov loop Φ vanishes there small T. 2+1 not preserved any θ, but becomes zero θconf < The phase defined by 0 realized, even if does have exactly. In θ–T plane, a critical endpoint of...
The equation of state and the phase diagram in two-flavor quantum chromodynamics (QCD) are investigated by Polyakov-loop extended Nambu–Jona-Lasinio (PNJL) model with an entanglement vertex between chiral condensate Polyakov loop. entanglement-PNJL (EPNJL) reproduces lattice QCD (LQCD) data at μ ⩾ 0 better than PNJL model. Hadronic degrees freedom taken into account free-hadron-gas approximation volume-exclusion effect due to hadron generation. improve agreement EPNJL LQCD particularly low...
We investigate differences and similarities between fundamental fermions adjoint in SU(N) gauge theories. The theory with possesses ZN symmetry only the limit of infinite fermion mass, whereas does have for any mass. flavor-dependent twisted boundary condition (FTBC) is then imposed on so that can possess show FTBC fermions, using Polyakov-loop extended Nambu--Jona-Lasinio (PNJL) model. In mean-field level, PNJL model has dynamics similar to confinement/deconfinement transition related...
We investigate the interplay between Z_{Nc} symmetry and emergence of quarkyonic phase, adding flavor-dependent complex chemical potentials \mu_f=\mu+iT\theta_f with (\theta_f)=(0, \theta, -\theta) to Polyakov-loop extended Nambu-Jona-Lasinio (PNJL) model. When \theta=0, PNJL model \mu_f agrees standard real potential \mu. \theta=2\pi/3, meanwhile, has exactly for any \mu, so that phase exists at small T large Once \theta varies from 2\pi/3, only on a line T=0 \mu larger than dynamical quark...
We investigate theta-vacuum effects on the QCD phase diagram for realistic $2+1$ flavor system, using three-flavor Polyakov-extended Nambu-Jona-Lasinio (PNJL) model and entanglement PNJL as an extension of model. The make chiral transition sharper. For large angle becomes first order even if quark number chemical potential is zero, when coupling between condensate Polyakov loop taken into account. finally propose a way circumventing sign problem lattice with finite theta.
<b>BACKGROUND AND PURPOSE:</b> Rapid uptake of the calcium analog manganese (Mn<sup>2+</sup>) into spontaneous pituitary adenoma during MR imaging aged rats generated hypothesis that neuroendocrine tumors may have a corresponding increase in influx required to trigger hormonal release. A goal this study was investigate potential for clinical evaluation by combined with administration Mn<sup>2+</sup> (Mn-MR imaging). <b>MATERIALS METHODS:</b> Mn-MR used characterize dynamic normal rat gland...
Theta vacuum effects on the QCD phase structure in \mu-T plane are studied by using Polyakov-loop extended Nambu-Jona-Lasinio model and its extension, where \mu is quark chemical potential T temperature, respectively. As parameter \theta of theta increases, chiral transition becomes stronger. For large \theta, it eventually first order even at zero \mu.
We investigate the chemical-potential ($\ensuremath{\mu}$) dependence of static-quark free energies in both real and imaginary $\ensuremath{\mu}$ regions, performing lattice QCD simulations at extrapolating results to real-$\ensuremath{\mu}$ region with analytic continuation. Lattice calculations are done on a ${16}^{3}\ifmmode\times\else\texttimes\fi{}4$ clover-improved two-flavor Wilson fermion action renormalization-group-improved Iwasaki gauge action. Static-quark potentials evaluated...
Abstract Although adoptive transfer of T cells genetically engineered to express chimeric antigen receptor (CAR) or T-cell (TCR) has been actively developed and applied into clinic recently, further improvement these modalities is highly demanded, especially in terms its efficacy. Because we previously revealed the profound enhancement antitumor effects CAR by concomitant expression IL7 CCL19, this study explored a potential IL7/CCL19 production technology augment TCR cells....
A helical π-conjugated poly(N-isobutyl-3-carbazole acetylene), P(iBCzA) was stereoregularly prepared using an [Rh(norbornadine)Cl]2–triethylamine catalyst in toluene at 25 °C to determine the detailed geometrical and spatial structures a tetrahydrofuran (THF) solution solid phase. P(iBCzA), which has bright orange color, obtained yield of 90%. The 2D NMR spectrum THF-d8 50 indicated that extraordinarily extended helix produced. WAXS pattern showed formation tetragonal crystal packed with...
The average phase factor $⟨{e}^{2i\ensuremath{\theta}}⟩$ of the QCD determinant is evaluated at finite quark chemical potential (${\ensuremath{\mu}}_{\mathrm{q}}$) with two-flavor version Polyakov-loop extended Nambu--Jona-Lasinio model scalar-type eight-quark interaction. For ${\ensuremath{\mu}}_{\mathrm{q}}$ larger than half pion mass ${m}_{\ensuremath{\pi}}$ vacuum, only when Polyakov loop $\ensuremath{\sim}0.5$, indicating that lattice feasible in deconfinement phase. A critical end...
Charge conjugation ($C$) and parity ($P$) are exact symmetries at $\ensuremath{\theta}=\ensuremath{\pi}$ $\ensuremath{\Theta}\ensuremath{\equiv}\ensuremath{\mu}/(iT)=\ensuremath{\pi}$, where $\ensuremath{\theta}$ is the parameter of so-called vacuum, $\ensuremath{\mu}$ imaginary quark-number chemical potential $T$ temperature. Spontaneous breakings these discrete investigated by Polyakov-loop extended Nambu--Jona-Lasinio model. At zero $T$, $P$ symmetry spontaneously broken while $C$...