A5084831624- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Eosinophilic Esophagitis
- Respiratory and Cough-Related Research
- Celiac Disease Research and Management
- Urologic and reproductive health conditions
- Adipose Tissue and Metabolism
- Urological Disorders and Treatments
- Hormonal Regulation and Hypertension
- Agricultural safety and regulations
- Microscopic Colitis
- Diet and metabolism studies
- Research on scale insects
- Banana Cultivation and Research
- Parvovirus B19 Infection Studies
- Blood groups and transfusion
- Child Nutrition and Feeding Issues
- Insect Pheromone Research and Control
- Airway Management and Intubation Techniques
- Plant Reproductive Biology
- Pesticide Exposure and Toxicity
University of Messina
2013-2024
Istituto Ortopedico Gaetano Pini
2020-2024
Ospedale Sant'Anna
2022
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2020-2021
University of Zurich
2021
Pollen allergy poses a significant health and economic burden in Europe. Disease patterns are relatively homogeneous within Central Northern European countries. However, no study broadly assessed the features of seasonal allergic rhinitis (SAR) across different Southern countries with standardized approach.
Abstract Background Pollen food allergy syndrome (PFAS) is a frequently underdiagnosed disease due to diverse triggers, clinical presentations, and test results. This especially relevant in geographic areas with broad spectrum of pollen sensitization, such as Southern Europe. Objectives To elucidate similarities differences PFAS nine European centers identify associated characteristics unique markers PFAS. Methods As part the @IT.2020 Multicenter Study, 815 patients seasonal allergic...
Abstract Peanut allergy affects about 1%–3% of the pediatric population in world, with an important increase last decades. Nowadays, international guidelines recommend early introduction peanuts infant diet, poor information quantity and frequency intake. Allergen immunotherapy may represent only therapeutic strategy able to modify natural history peanut allergy. In particular, oral showed most promising results terms efficacy, but significant rates adverse reactions, mostly...
The adequate definition of pollen seasons is essential to facilitate a correct diagnosis, treatment choice, and outcome assessment in patients with seasonal allergic rhinitis. A position paper by the European Academy Allergy Clinical Immunology (EAACI) proposed season definitions for Northern Middle Europe.To test EAACI six Mediterranean cities seven taxa.As part @IT.2020 multi-center study, counts Poaceae, Oleaceae, Fagales, Cupressaceae, Urticaceae (Parietaria spp.), Compositae (Ambrosia...
Allergic respiratory diseases, such as asthma and allergic rhinitis, are global health issues have had an increasing prevalence in the last decades. Allergen-specific immunotherapy (AIT) is only curative treatment for rhinitis asthma, it has a disease-modifying effect. AIT generally administered by two routes: subcutaneous (SCIT) sublingual (SLIT). Local side effects common, but usually well-tolerated self-limited. However, systemic rare, associated with uncontrolled bronchial obstruction,...
Currently, severe allergic asthma and food allergy in children represent an important public health problem with medical, psychosocial economic impacts. Omalizumab is a humanized monoclonal anti-IgE antibody, approved for refractory chronic urticaria. It has been widely used clinical practice as add-on therapy patients uncontrolled asthma. In recent years there seen the emergence of epidemic increasing allergy, which represents main cause anaphylaxis children. The standard care strictly...
Abstract Atopic dermatitis (AD) is a chronic remitting‐relapsing inflammatory skin disorder. Due to the multifactorial pathogenesis, there are numerous therapeutic management approaches, mainly based on symptomatic treatments. In recent years, allergen immunotherapy (AIT) has been progressively advanced as targeted disease‐modifying treatment of allergic disease. The most guideline from American Academy Dermatology concludes that data available do not support its use in AD. Joint Task Force...
Omalizumab is a monoclonal antibody, targeting Fc receptor of IgE, approved for the treatment allergic asthma and chronic spontaneous urticaria. Its utility in atopic dermatitis appears controversial from data literature since molecule well tolerated but it seems less effective than other medications used adult patients (eg, Dupilumab). At present, use Dupilumab not pediatric therefore there are no second level treatments available this age group. Here we report two clinical cases (15 16...
Coeliac disease (CD) is frequently underdiagnosed with a consequent heavy burden in terms of morbidity and health care costs. Diagnosis CD based on the evaluation symptoms anti-transglutaminase antibodies IgA (TGA-IgA) levels, values above tenfold increase being basis biopsy-free diagnostic approach suggested by present guidelines. This study showcased largest screening project for carried out to date school children (n=20,000) aimed at assessing accuracy minimally invasive finger prick...
48, XXYY is a very rare sex chromosome aneuploidy, characterized by both an extra X and Y with prevalence of 1:18,000–1:40,000. Most patients are diagnosed prenatally cytogenetic examination amniotic fluid, or during the first years life because severe developmental delay, cognitive impairment behavioural disorders. This syndrome shares two findings Klinefelter syndrome, namely tall stature hypergonadotropic hypogonadism but at this time no genital anomalies have been reported in tetrasomy....
Food allergy (FA) negatively affects health-related quality of life (HR-QoL) children and caregivers. To date, no questionnaire self-compiling assessing the HR-QoL in pre-school with FA is available. The aim this study to develop validate a self-administered, rapid easy evaluate ≥ 7 years IgE-mediated FA.
Atopic dermatitis (AD) is the most common chronic skin disease in children, with an increasing prevalence past three decades. Adequate treatment prescribed for individual patient based on symptoms and severity. However, further underlying diagnosis should be researched when therapeutic strategies fail lesions pruritus persist. We reported herein case of a 19-month-old infant history AD unresponsive to due type 2 progressive familial intrahepatic cholestasis (PFIC). A new homozygous mutation...
Food allergy is a potentially life-threatening condition and significant public health concern worldwide. The current management includes food avoidance use of emergency medications. growing prevalence drives research towards specific allergen immunotherapy (AIT), which represents potential disease-modifying approach. AIT consists the progressive administration amounts offending in order to induce desensitisation, creating an increase reaction threshold with regular exposure allergen. can be...
Atopic dermatitis (AD) is a chronic remitting-relapsing inflammatory skin disorder. Due to the multifactorial pathogenesis, there are numerous therapeutic management approaches, mainly based on symptomatic treatments. In recent years Allergen Immunotherapy (AIT) has been progressively advanced as targeted disease-modifying treatment of allergic disease. The most guideline from American Academy Dermatology concludes that data available do not support its use in AD. Joint Task Force and...
Context : Asthma is the most common inflammatory disease of airways in children. The term problematic asthma used to describe children with chronic symptoms or acute severe exacerbations, both, not responding standard therapy. Case Presentation We case a 5 years old girl history recurrent respiratory infections and since first months life, poor response conventional therapies (antibiotics, high dose corticosteroids combined long-acting β2 agonists oral leukotriene-receptor antagonists). In...
Hydrops fetalis (HF) is a serious fetal condition defined as an abnormal fluid accumulation in extravascular compartments and body cavities caused by either immune or non conditions. Immune hydrops hemolysis medi¬ated circulating maternal antibodies to red blood cell antigens. Its most common determinant rhesus incompatibility. Systemic Lupus Eritematosus (SLE) another rare cause of hydrops, when the pregnancy complicated presence third degree congenital heart block (CHB). The Neonatal...