- Proteins in Food Systems
- Liver Disease Diagnosis and Treatment
- Food Chemistry and Fat Analysis
- Microencapsulation and Drying Processes
- Food composition and properties
- Protein Hydrolysis and Bioactive Peptides
- Polysaccharides Composition and Applications
- Dye analysis and toxicity
- Phytoestrogen effects and research
- Endoplasmic Reticulum Stress and Disease
- Enzyme Catalysis and Immobilization
- Biochemical Analysis and Sensing Techniques
- Water Quality Monitoring and Analysis
- Advanced Glycation End Products research
- Tea Polyphenols and Effects
- Amino Acid Enzymes and Metabolism
- Enzyme Structure and Function
- Meat and Animal Product Quality
- Pesticide Residue Analysis and Safety
- Garlic and Onion Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Pickering emulsions and particle stabilization
- Microbial Metabolic Engineering and Bioproduction
- Food Quality and Safety Studies
- Food and Agricultural Sciences
State Key Laboratory of Food Science and Technology
2015-2025
Jiangnan University
2015-2025
Food Research Institute
2025
Central South University
2022-2024
Second Xiangya Hospital of Central South University
2022-2024
Quanzhou Normal University
2022
Wuxi Institute of Technology
2014
A β-Lg-EGCG covalent conjugate is formed by linking the amino group of a lysine residue and EGCG; antioxidant capacity EGCG induced β-Lg–EGCG conjugates causes significant decrease.
Loop dynamics redesign is an important strategy to manipulate protein function. Cellobiose 2-epimerase (CE) and other members of its superfamily are widely used for diverse industrial applications. The structural feature the loops connecting barrel helices contributes greatly differences in their functional characteristics. Inspired by in-silico mutation with molecular (MD) simulation analysis, we propose a identifying disulfide bond candidates based on prediction flexibility residue–residue...
The catalytic performance of hierarchically porous niobium phosphate (NbP) supported magnesia for the glucose isomerization to fructose, was investigated under atmospheric air atmosphere. Porous NbP showed improved support effects on MgO in comparison other metal oxides tested isomerization. Also, amount and distribution basic sites were largely changed by supporting NbP. Although textural properties reduced solid acids formed MgO/NbP catalysts, promoted increasing magnesium content. maximum...
Abstract BACKGROUND Recombinant plant‐based whipping cream (RSWC) has been widely studied in recent years. The present study investigated the effects of soybean protein and its hydrolysates on stability physical properties RSWC. RSWC was made with 28% oil bodies 4% additional soy proteins or hydrolysates. used were isolate, 7S, 11S, body protein, isolate hydrolyzed by pepsin (SPHPe) papain (SPHPa). RESULTS SPHPa containing a large amount small‐molecule polypeptide had lowest apparent...
With the popularity of multi-residue pesticide analysis based on quick, easy, cheap, effective, rugged, and safe (QuEChERS) cleanup liquid chromatography–mass spectrometry (LC-MS), matching optimal matrix-matched calibration protocols LC-MS conditions to reduce matrix effects (MEs) has become a crucial task for analysts in their routines. However, dozens hundreds analytes single run generate increasingly multi-dimensional ME data, requiring appropriate tools handle these data sets....
Non-alcoholic fatty liver disease (NAFLD) presents as a common characterized by an indistinct pathogenesis. Disulfidptosis is recently identified mode of cell death. This study aimed to investigate the potential role disulfidptosis-related genes (DRGs) in pathogenesis NAFLD.
Nattokinase (NK), a serine protease with high thrombolytic activity, has significant potential for application in foods intended special health benefits. However, the NK production wild-type Bacillus subtilis natto is relatively low. In this study, high-yielding and genetically stable mutant strain (B. JNC002.001, 300.0 ± 4.7 FU/mL) was obtained through atmospheric room temperature plasma (ARTP) mutagenesis. It increased activity by 1.84 times compared to initial SD2, demonstrating prospects...
Insulin resistance (IR) is a complex metabolic disorder characterized by diminished insulin sensitivity, leading to impaired glucose uptake and potential progression hyperglycemia diabetes. While lifestyle modifications are essential, the limitations of current pharmacological interventions highlight need for natural products with therapeutic benefits. This study introduces two novel dihydroquercetin (DHQ) derivatives, 8-hydroxy-dihydroquercetin (H-DHQ)...
The methoxylated modification of flavonoids has been reported to enhance stability and permeability; however, its effect on the improvement activity is not clear. In this study, Citrus depressa flavonoid O-methyltransferase 5 Sorghum vulgare 7-O-methyltransferase were recombinantly expressed successfully converted quercetin (QUE) into eight products, which isolated identified with a purity exceeding 95%. All products except rhamnetin (RHA) showed improved stability, while only 5,7,3',4'-EMQ,...
Abstract The effect of partial enzymatic hydrolysis soy protein isolate (SPI) on its foaming properties is investigated in this study. Enzymes different origin, including papain, alcalase, and pancreatin, were used. Foaming (foaming capacity foam stability) measured their relationships with physicochemical characteristics such as degree hydrolysis, molecular weight hydrolysates, surface tension investigated. Papain hydrolyzed SPI hydrolysates found to be the best terms improved stability....
Metabolic-associated fatty liver disease (MAFLD) affects approximately a quarter of the global population. Identification key genes and pathways involved in hepatic lipid metabolism is utmost importance for diagnosis, treatment, prevention MAFLD. In this study, differentially expressed were identified through whole-genome transcriptional analysis tissue from MAFLD patients healthy controls, series metabolism-related molecules obtained pathway analysis. Subsequently, we focused on Iroquois...
A one-step extraction method for analyzing 11 polar heterocyclic aromatic amines using UHPLC-MS/MS was proposed and applied to meat commodities.