A5110166956- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Virus-based gene therapy research
- Reproductive biology and impacts on aquatic species
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Viral Infectious Diseases and Gene Expression in Insects
- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- RNA Interference and Gene Delivery
- Parvovirus B19 Infection Studies
- Genomics and Phylogenetic Studies
- Estrogen and related hormone effects
- RNA and protein synthesis mechanisms
- Plant Virus Research Studies
- Acute Kidney Injury Research
- Genetic diversity and population structure
- Effects and risks of endocrine disrupting chemicals
- Traditional Chinese Medicine Analysis
- MicroRNA in disease regulation
- Animal Genetics and Reproduction
- Invertebrate Immune Response Mechanisms
- Plant and Fungal Interactions Research
- Microbial Community Ecology and Physiology
- RNA Research and Splicing
- Congenital Diaphragmatic Hernia Studies
State Key Laboratory of Food Science and Technology
2008-2025
Jiangnan University
2008-2025
Guangxi Medical University
2025
Xuzhou Medical College
2025
Wuhan University
2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Liuzhou General Hospital
2024
Wuhan Institute of Virology
2013-2023
Chinese Academy of Sciences
2013-2023
Full-length and partial genome sequences of four members the genus Aquareovirus , family Reoviridae (Golden shiner reovirus, Grass carp Striped bass reovirus golden ide reovirus) were characterized. Based on sequence comparison, unclassified was shown to be a member species C . The status another aquareovirus, also examined. Sequence analysis showed that it did not belong A or but assessment its relationship B D E F hampered by absence genetic data from these species. In agreement with...
Summary The Pelagibacterales order (SAR11) in Alphaproteobacteria dominates marine surface bacterioplankton communities, where it plays a key role carbon and nutrient cycling. SAR11 phages, known as pelagiphages, are among the most abundant phages ocean. Four pelagiphages that infect Pelagibacter HTCC1062 have been reported. Here, we report 11 new Podoviridae family. Comparative genomics classified these into HTVC019Pvirus genus, which includes previously reported HTVC011P HTVC019P....
Most double-stranded RNA (dsRNA) viruses transcribe plus strands within a common innermost capsid shell. This process requires coordinated efforts by RNA-dependent polymerase (RdRp) together with other proteins and genomic RNA. Here we report the near-atomic resolution structure of RdRp protein VP2 in complex its cofactor VP4 an aquareovirus using 200-kV cryoelectron microscopy symmetry-mismatch reconstruction. The these enabled us to observe elaborate nonicosahedral double-layered...
Abstract Sophora tonkinensis belongs to genus of the Fabaceae family. It is mainly distributed in ridge and peak regions limestone areas western China has high medicinal value important ecological functions. Wild populations S. are danger need urgent conservation. Furthermore, wild resources very limited relative needs market, many adulterants present on market. Therefore, a method for authenticating its at molecular level needed. Chloroplast genomes valuable sources genetic markers...
The present study was conducted to test the hypothesis that a free radical formed and mediated formation of 3-monochloropropanediol (3-MCPD) fatty acid diesters, group food contaminants, from diacylglycerols at high temperature under low-moisture condition for first time. presence radicals in vegetable oil kept 120 °C 20 min demonstrated using an electron spin resonance (ESR) spectroscopy examination with 5,5-dimethylpyrroline-N-oxide (DMPO) as trap agent. ESR investigation also showed...
Many major marine bacterial lineages such as SAR11, Prochlorococcus, SAR116, and several Roseobacter have members that are abundant, relatively slow-growing, genome streamlined. The isolation of phages infect SAR11 SAR116 demonstrated the dominance these in virosphere. However, no been isolated from bacteria RCA lineage, another abundant group bacteria. In this study, seven three different strains were characterized. All belong to Podoviridae family sizes ranging 39.6 58.1 kb. Interestingly,...
The hairpin II of U1 snRNA can bind U1A protein with high affinity and specificity. NMR spectra suggest that the loop region apo-RNA is largely unstructured undergoes a transition from to well-folded upon U1Abinding. However, mechanism RNA folding coupled binding poorly understood. To get an insight into mechanism, we have performed explicit-solvent molecular dynamics (MD) study kinetics bound apo-RNA. Room-temperature MD simulations conformation has significant adjustment becomes more...
Insulin resistance (IR) is a complex metabolic disorder characterized by diminished insulin sensitivity, leading to impaired glucose uptake and potential progression hyperglycemia diabetes. While lifestyle modifications are essential, the limitations of current pharmacological interventions highlight need for natural products with therapeutic benefits. This study introduces two novel dihydroquercetin (DHQ) derivatives, 8-hydroxy-dihydroquercetin (H-DHQ)...