A5036033265- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Plant Virus Research Studies
- Aquaculture disease management and microbiota
- Respiratory viral infections research
- Marine and coastal ecosystems
- Wildlife Ecology and Conservation
- Microbial infections and disease research
- Methane Hydrates and Related Phenomena
- Ecology and Vegetation Dynamics Studies
- Vibrio bacteria research studies
- Antibiotic Resistance in Bacteria
- Environmental DNA in Biodiversity Studies
- Land Use and Ecosystem Services
- Marine Biology and Ecology Research
- Polyomavirus and related diseases
- Viral gastroenteritis research and epidemiology
- Ocean Acidification Effects and Responses
- Plant and animal studies
- Animal Ecology and Behavior Studies
- Soil Carbon and Nitrogen Dynamics
- Species Distribution and Climate Change
- Coastal wetland ecosystem dynamics
- Gut microbiota and health
Shenzhen University
2022-2025
Sun Yat-sen Memorial Hospital
2025
Sun Yat-sen University
2011-2025
Shenzhen Institutes of Advanced Technology
2025
Yanbian University
2025
Inner Mongolia University
2024-2025
Xiamen University
2015-2024
Chinese Academy of Forestry
2022-2024
Harbin Medical University
2024
First Affiliated Hospital of Harbin Medical University
2024
Mangroves are ecologically and economically important forests of the tropics. As one most carbon-rich biomes, mangroves account for 11% total input terrestrial carbon into oceans. Although viruses considered to significantly influence local global biogeochemical cycles, little information is available regarding community structure, genetic diversity ecological roles in mangrove ecosystems.Here, we utilised viral metagenomics sequencing virome-specific bioinformatics tools study communities...
Our previous studies have shown that high alcohol-producing Klebsiella pneumoniae (HiAlc Kpn) in the intestinal microbiome could be one of causes non-alcoholic fatty liver disease (NAFLD). Considering antimicrobial resistance K. and dysbacteriosis caused by antibiotics, phage therapy might potential treatment HiAlc Kpn-induced NAFLD, because specificity targeting bacteria. Here, we clarified effectiveness male mice with steatohepatitis. Comprehensive investigations including transcriptomes...
Abstract Seamounts are globally distributed across the oceans and form one of major oceanic biomes. Here, we utilized combined analyses bulk metagenome virome to study viral communities in seamount sediments western Pacific Ocean. Phylogenetic protein-sharing network demonstrate extensive diversity previously unknown clades. Inference virus-host linkages uncovers interactions between viruses dominant prokaryote lineages, suggests that play significant roles carbon, sulfur, nitrogen cycling...
Summary Viruses have been detected in the different stages of wastewater treatment plants (WWTPs) at concentrations 10 8 –10 ml −1 virus‐like particles (VLPs), 10–1000 times higher than natural aquatic environments, suggesting that WWTPs can be considered as an important reservoir and source viruses. This study revealed novel diversity function with DNA viral communities influent, activated sludge, anaerobic digester, effluent a domestic WWTP using metagenomics. was very specific...
Microbial degradation of dissolved organic carbon (DOC) in aquatic environments can cause oxygen depletion, water acidification, and CO2 emissions. These problems are caused by labile DOC (LDOC) not refractory (RDOC) that resists is thus a sink. For nearly century, chemical demand (COD) has been widely used for assessment pollution systems. Here, we show through multicountry survey experimental studies COD an appropriate proxy microbial degradability matter because it oxidizes both LDOC...
Long noncoding RNAs known as roX (RNA on the X) are crucial for male development in Drosophila, their loss leads to lethality from late larval stages. While recognized role sex-chromosome dosage compensation, ensuring balanced expression of X-linked genes both sexes, potential influence autosomal gene regulation remains unexplored. Here, using an integrative multi-omics approach, we show that not only govern X chromosome but also target autosomes lack male-specific lethal (MSL) complex...
Hospitals play an important role in the spread of antibiotic resistance genes (ARGs) and antimicrobial (AMR). The ARGs present hospital wastewater tend to accumulate activated sludge, with different exhibiting varying migration rates. As a result, sludge water produced during treatment process may be significant source entering environment. Despite this, research into behavior concentration dewatering remains limited. This study hypothesizes that might exhibit new behaviors concentration....
As aquaculture continues to expand globally, diseases caused by Vibrio species are becoming increasingly prevalent. Vibriosis encompasses a range of infections, which can lead symptoms such as skin lesions, hemorrhaging, and high mortality rates in fish shellfish, especially high-density farming systems, resulting significant economic losses. Simultaneously, the extensive use antibiotics has fostered emergence antibiotic-resistant bacteria, exacerbated disease outbreaks, complicated control...
Viruses are ubiquitous and cause significant mortality in marine bacterial archaeal communities. Little is known about the role of viruses sub-seafloor biosphere, which hosts a large fraction all microbes on Earth. We quantified characterized sediments from Baltic Sea. The results show that Sea biosphere harbors highly abundant with densities up to 1.8 × 1010 cm-3. High potential viral production down 37 meters below seafloor ca. 6000-years-old infected prokaryotic cells visible by...
Summary The Pelagibacterales order (SAR11) in Alphaproteobacteria dominates marine surface bacterioplankton communities, where it plays a key role carbon and nutrient cycling. SAR11 phages, known as pelagiphages, are among the most abundant phages ocean. Four pelagiphages that infect Pelagibacter HTCC1062 have been reported. Here, we report 11 new Podoviridae family. Comparative genomics classified these into HTVC019Pvirus genus, which includes previously reported HTVC011P HTVC019P....
Microbes drive ecosystems and their viruses manipulate these processes, yet the importance of tidal functioning on estuarine microbes remains poorly elucidated. Here, an integrative investigation patterns in viral microbial communities inherent interactions over entire spring-neap cycle was conducted along a macrotidal subtropical estuary. The abundances oscillated significantly with relatively higher observed at spring tide compared to neap tide. distinct dynamic bacterial production...
Tailed bacteriophages (order, Caudovirales) account for the majority of all phages. However, long flexible tail siphophages hinders comprehensive investigation mechanism viral gene delivery. Here, we report atomic capsid and in-situ structures machine marine siphophage, vB_DshS-R4C (R4C), which infects Roseobacter. The R4C virion, comprising 12 distinct structural protein components, has a unique five-fold vertex icosahedral that allows genome specific position interaction pattern tube...
Summary To gain a better understanding of the interactions among bacteria, viruses and flagellates in coastal marine ecosystems, we investigated effect viral lysis protistan bacterivory on bacterial abundance, production diversity [determined by 16S rRNA gene polymerase chain reaction (PCR) denaturing gradient gel electrophoresis (DGGE)] three sites with different nutrient supplies Hong Kong. Six experiments were set up using filtration dilution methods to develop virus, flagellate...
To explore the charge transport through metalla-aromatics building blocks, three metallacycles complexes were synthesized, and their single-molecule conductances characterized by using mechanically controllable break junction technique. It is found that conductance of with phosphonium group more than 1 order magnitude higher without group. X-ray diffraction UV-vis absorption spectroscopy suggested attached makes delocalized, which shortened preferred pathway significantly enhanced...
The Roseobacter clade is abundant and widespread in marine environments plays an important role oceanic biogeochemical cycling. In this present study, a lytic siphophage (labeled vB_DshS-R5C) infecting the strain type of Dinoroseobacter shibae named DFL12T, which part clade, was isolated from oligotrophic South China Sea. Phage R5C showed narrow host range, short latent period low burst size. genome length phage 77, 874 bp with G+C content 61.5%. Genomic comparisons detected no matches...
We studied the interplay between quantum interference (QI) and molecular asymmetry in charge transport through a single molecule. Eight compounds with five-membered core rings were synthesized, their single-molecule conductances characterized using mechanically controllable break junction technique. It is found that symmetric molecules are more conductive than asymmetric isomers there no statistically significant dependence on aromaticity of core. In contrast, we find experimental evidence...