Long Wang

ORCID: 0000-0003-3891-0010
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About
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Research Areas
  • Microbial Community Ecology and Physiology
  • Bacteriophages and microbial interactions
  • Methane Hydrates and Related Phenomena
  • Genomics and Phylogenetic Studies
  • Marine and coastal ecosystems
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Protist diversity and phylogeny
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Remote Sensing in Agriculture
  • Invertebrate Immune Response Mechanisms
  • Polar Research and Ecology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Metal Extraction and Bioleaching
  • Parasite Biology and Host Interactions
  • Spectroscopy and Laser Applications
  • Atmospheric Ozone and Climate
  • Atmospheric and Environmental Gas Dynamics
  • Neurological Disease Mechanisms and Treatments
  • Plant Virus Research Studies
  • Respiratory viral infections research
  • Identification and Quantification in Food
  • Wastewater Treatment and Nitrogen Removal
  • Minerals Flotation and Separation Techniques
  • Marine Bivalve and Aquaculture Studies

Chinese Academy of Sciences
1998-2025

Jilin Agricultural University
2023-2025

Shanghai Institute of Materia Medica
2023-2025

Huaiyin Normal University
2021-2024

Shanghai Ocean University
2021-2024

Xiamen University
2020-2024

Institute of Mechanics
2024

Changchun Institute of Optics, Fine Mechanics and Physics
2017-2024

Hunan Agricultural University
2024

Chengdu University of Traditional Chinese Medicine
2024

Abstract Background Ischemic stroke is the second leading cause of death globally. The narrow time window for administering effective thrombolytic therapy motivates search alternative prevention strategies. Microglia and astrocyte activation-mediated inflammation play a pivotal role in ischemic injury. Cottonseed oil (CSO) has been shown to exert anti-inflammatory effects against peripheral tissue injury, although CSO mostly used as solvent lipid-soluble drugs. However, neuroprotection not...

10.1186/s12974-020-01946-7 article EN cc-by Journal of Neuroinflammation 2020-09-11

Bacterial communities are called another "organ" for aquatic animals and their important influence on the health of host has drawn increasing attention. Thus, it is to study relationships between bacterial communities. Here, associated with Litopenaeus vannamei larvae at different healthy statuses (diseased healthy) growth stages (i.e. zoea, mysis early postlarvae periods) were examined using 454-pyrosequencing 16S rRNA gene. significant difference observed diseased rearing water, several...

10.3389/fmicb.2017.01362 article EN cc-by Frontiers in Microbiology 2017-07-18

The Mariana Trench harbors a substantial number of infective viral particles. However, very little is known about the identity, survival strategy, and potential functions viruses in trench sediments.

10.1128/msystems.01358-21 article EN mSystems 2022-01-04

The human voltage-gated potassium channel KCNQ2/KCNQ3 carries the neuronal M-current, which helps to stabilize membrane potential. KCNQ2 can be activated by analgesics and antiepileptic drugs but their activation mechanisms remain unclear. Here we report cryo-electron microscopy (cryo-EM) structures of KCNQ2-CaM in complex with three activators, namely drug cannabidiol (CBD), lipid phosphatidylinositol 4,5-bisphosphate (PIP2), HN37 (pynegabine), an clinical trial, either closed or open...

10.1038/s41467-023-42416-x article EN cc-by Nature Communications 2023-10-19

Abstract miR155 is a regulator of immune cell development and function that generally thought to be immunostimulatory. However, we report here genetic ablation renders mice resistant chemical carcinogenesis the growth several transplanted tumors, suggesting functions in immunosuppression tumor promotion. Host deficiency promoted overall antitumor immunity despite finding defective responses miR155-deficient dendritic cells T cells. Further analysis compartments revealed regulated...

10.1158/0008-5472.can-14-2331 article EN Cancer Research 2014-12-11

A metagenomic analysis of the viral community from five surface and deep sea water (>2000 m below surface, mbs) samples collected central basin South China Sea adjacent Northwest Pacific Ocean during July-August 2017 was conducted herein. We builded up a DNA virome (SCSV) dataset 29,967 Operational Taxonomic Units (vOTUs), which is comparable to populations original Tara Malaspina expeditions. The most abundant widespread were uncultivated viruses annotated metagenomics. Only 74 37 vOTUs...

10.3389/fmicb.2019.01951 article EN cc-by Frontiers in Microbiology 2019-08-23

The metabolism of methane in anoxic ecosystems is mainly mediated by methanogens and methane-oxidizing archaea (MMA), key players global carbon cycling. Viruses are vital regulating their host fate ecological function. However, our knowledge about the distribution diversity MMA viruses interactions with hosts rather limited. Here, searching metagenomes containing mcrA (the gene coding for α-subunit methyl-coenzyme M reductase) from a wide variety environments, 140 viral operational taxonomic...

10.1038/s43705-022-00135-2 article EN cc-by ISME Communications 2022-06-28

The increasing consumption of antiepileptic drugs (AEDs) has led to their widespread presence in aquatic environments, which poses a serious threat human health and organisms. However, there is currently lack review provide basic data research directions for future scholars. This article was carried out summarize toxicity, analytical methods, concentrations, transformation mechanisms fate AEDs metabolites/transformation products environments according existing literature. were widely found...

10.1080/10643389.2023.2209010 article EN Critical Reviews in Environmental Science and Technology 2023-05-11

As photoautotrophs, phytoplankton are generally present in the euphotic zone of ocean, however, recently healthy cells were found to be also ubiquitous dark deep sea, i.e., at water depths between 2000 and 4000 m. The distributions communities much deeper waters, such as hadal zone, unclear. In this study, vertical distribution pico- nano-phytoplankton (PN) from surface 8320 m, including epipelagic, mesopelagic, bathypelagic, zones, investigated via both 18S p23S rRNA gene analysis...

10.3389/fmicb.2018.02289 article EN cc-by Frontiers in Microbiology 2018-09-26

Bacteriophages play critical roles in impacting microbial community succession both ecologically and evolutionarily. Although the majority of phage genetic diversity has been increasingly unveiled, phages infecting members important genus

10.1128/msphere.00454-21 article EN cc-by mSphere 2021-06-13

ABSTRACT The relationship between physical activity and sleep quality is a critical area of investigation, given the importance both behaviours for health disease. Despite common use running wheels to assess circadian rhythms exercise, their impact on has not been thoroughly explored. Here, we present detailed analysis how voluntary affected sleep/wakefulness duration, architecture electrophysiological characteristics in mice. Sequential electroencephalogram (EEG) assessments revealed that...

10.1111/jsr.70023 article EN Journal of Sleep Research 2025-03-18

In soybean fields across Northeast China, Thrips flavus Schrank (Thysanoptera, Thripidae) populations are increasing, posing a significant threat to production. The aim of this study was evaluate the toxicity, insecticide efficacy, and field performance thirty insecticides against T. flavus. Laboratory bioassays revealed that fenthion (LC50 = 2.26 mg/L), sulfoxaflor 4.28 cyetpyrafen 4.94 imidacloprid 6.16 mg/L) exhibited highest toxicity Pot experiments were subsequently conducted assess...

10.3390/insects16040405 article EN cc-by Insects 2025-04-11

TanSat is an important satellite in the Chinese Earth Observation Program which designed to measure global atmospheric CO 2 concentrations from space.The first superhigh-resolution grating spectrometer for measuring aboard TanSat.This a suite of three spectrometers that make coincident measurements reflected sunlight near-infrared band near 1.61 and 2.06 μm molecular oxygen A-band (O A) at 0.76 μm.Their spectral resolving power (λ/λ) ∼19 000, ∼12 800, 250 O A, weak absorption carbon dioxide...

10.1109/tgrs.2018.2829224 article EN IEEE Transactions on Geoscience and Remote Sensing 2018-05-23

The marine bacterium Alteromonas is prevalent in the global ocean with crucial ecological significance; however, little known about diversity and evolution of its bacteriophages that profoundly affect bacterial communities. Our study characterized a novel genus three newly isolated phages exhibited distinct infection strategy broad host spectrum small burst size.

10.1128/spectrum.01499-22 article EN cc-by Microbiology Spectrum 2022-07-11
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