A5100716974- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Polymer Surface Interaction Studies
- Dendrimers and Hyperbranched Polymers
- Catalytic C–H Functionalization Methods
- 3D Printing in Biomedical Research
- Osteoarthritis Treatment and Mechanisms
- Supramolecular Self-Assembly in Materials
- Surgical Sutures and Adhesives
- Advanced Sensor and Energy Harvesting Materials
- Nanoplatforms for cancer theranostics
- Advanced Materials and Mechanics
- Catalytic Cross-Coupling Reactions
- Conducting polymers and applications
- Wound Healing and Treatments
- Silicone and Siloxane Chemistry
- Hemostasis and retained surgical items
- Organic Electronics and Photovoltaics
- Periodontal Regeneration and Treatments
- biodegradable polymer synthesis and properties
- Membrane Separation Technologies
- Tissue Engineering and Regenerative Medicine
- Nanoparticle-Based Drug Delivery
University of Chinese Academy of Sciences
2016-2025
Beijing National Laboratory for Molecular Sciences
2016-2025
Chinese Academy of Sciences
2016-2025
Institute of Chemistry
2016-2025
Dalian Polytechnic University
2025
Guangxi University
2025
State Key Laboratory of Polymer Physics and Chemistry
2013-2024
Shanghai Institute of Materia Medica
2018-2024
Xinjiang Medical University
2024
First Affiliated Hospital of Xinjiang Medical University
2024
Hybrid ionically-covalently crosslinked double-network (DN) hydrogels are attracting increasing attention on account of their self-recovery ability and fatigue resistance, but relative low mechanical strength tedious performance adjustment severely limit applications. Herein, a new strategy to concurrently fabricate hybrid ionic-covalent DN modulate structures mechanics is reported, in which an situ formed chitosan ionic network incorporated by post-crosslinking the chitosan-based composite...
Conductive hydrogels have attracted intensive attention for versatile functions in flexible electronics because of their unique combination mechanical flexibility and conductivity. However, containing plenty water inevitably freeze at subzero temperature, leading to invalid with failed advantages negligible Moreover, the inferior elasticity fatigue resistance result unstable sensing performance poor reusability hydrogel-based electronics. Herein, a freezing-tolerant, high-sensitive, durable...
Current approaches to fabrication of nSC composites for bone tissue engineering (BTE) have limited capacity achieve uniform surface functionalization while replicating the complex architecture and bioactivity native bone, compromising application these nanocomposites in situ regeneration. A robust biosilicification strategy is reported impart a stable osteoinductive porous collagen scaffolds. The resultant possess native-bone-like structure nanosilica coating. osteoinductivity scaffolds...
Death happening due to massive hemorrhage has been involved in military conflicts, traffic accidents, and surgical injuries of various human disasters. Achieving rapid effective hemostasis save lives is crucial urgent bleeding situations. Herein, a covalent cross-linked AG-PEG glue based on extracellular matrix-like amino-gelatin (AG) PEG derivatives developed. The gelatinizes fast exhibits firm indiscriminate close adhesion with moist tissues upon being dosed. formed establishes an adhesive...
Abstract Double‐network (DN) hydrogels consisting of noncovalent interacting networks are highly desired due to their well‐controlled compositions and environmental friendliness, but the low water resistance always impairs mechanical strength. Here, an anti‐swelling hydrogel possessing core/shell architecture through rational regulation multiple weak interactions is prepared. A composite consists chitosan (CS) poly( N ‐acryloyl 2‐glycine) (PACG), readily forming shell‐structured DN after...
Graphene is a promising antioxidant for diolefin elastomers, due to its free-radical scavenging and gas barrier abilities.
Conductive hydrogels are capturing intensive attention for versatile applications in flexible wearable devices on account of their unique combination softness, stretchability, conductivity and biocompatibility. However, most the hydrogel sensors can only serve as single-type to detect strain or pressure, accompanied by a limited detection range. Moreover, poor anti-freezing performance is also serious problem be addressed practical applications. Herein, multi-model, large range sensor was...
The effectiveness of existing tissue-engineering cartilage (TEC) is known to be hampered by weak integration biocompatibility, biodegradation, mechanical strength, and microenvironment supplies. strategy hydrogel-based TEC holds considerable promise in circumventing these problems. Herein, a non-toxic, biodegradable, mechanically optimized double-network (DN) hydrogel consisting polyethylene glycol (PEG) kartogenin (KGN)-conjugated chitosan (CHI) constructed using simple soaking strategy....
In the current global crisis of antibiotic resistance, delivery systems are emerging to combat resistant bacteria in a more efficient manner. Despite significant advances nanocarriers, many challenges like poor biocompatibility, premature drug release, suboptimal targeting infection sites and short blood circulation time still challenging. To achieve targeted enhance antibacterial activity, here we reported kind pH-responsive nanoparticles by simply self-assembly an amphiphilic poly(ethylene...
Abstract Development of artificial biomaterials by mimicking extracellular matrix bone tissue is a promising strategy for regeneration. Hydrogel has emerged as type viable substitute, but its inhomogeneous networks and weak mechanics greatly impede clinical applications. Here, dual crosslinked gelling system developed with tunable architectures to promote osteogenic capacity. Polyhedral oligomeric silsesquioxane (POSS) designated rigid core surrounded six disulfide‐linked PEG shells two...
First-aid for severe traumatic injuries in the battlefield or pre-hospital environment, especially skin defects visceral rupture, remains a substantial medical challenge even context of rapidly evolving modern technology. Hydrogel-based biomaterials are highly anticipated excellent biocompatibility and bio-functional designability. Yet, inadequate mechanical bio-adhesion properties limit their clinical application. To address these challenges, kind multifunctional hydrogel wound dressing is...
Abstract Inflammation‐responsive hydrogels loaded with therapeutic factors are effective biomaterials for bone tissue engineering and regenerative medicine. In this study, a matrix metalloproteinase (MMP)‐responsive injectable hydrogel is constructed by integrating an MMP‐cleavable peptide (pp) into covalent tetra‐armed poly‐(ethylene glycol) (PEG) network precise drug release upon inflammation stimulation. To establish pro‐regenerative environment, phosphatidylserine (PS) encapsulated...
Graphene/natural rubber ( GE / NR ) nanocomposites were prepared by a modified latex mixing method combined with in situ chemical reduction. It was found that the nanosheets are well dispersed and have strong interfacial interaction . Thus, adding low content of can remarkably increase tensile strength initial modulus With incorporation as 0.5 phr , 48% an 80% achieved without sacrificing ultimate strain. But further increasing loading degrades Dynamic mechanical measurement indicates...
A general approach is proposed to synthesize Janus polymer/inorganic composite nanosheets. Onto the amine-group-terminated side of inorganic nanosheets, initiators are covalently bonded. By a favorable grafting from initiator-terminated side, responsive polymers, for example PDEAEMA and PNIPAM, synthesized by controlled polymerization ATRP or RAFT polymerization. Stable emulsions easily formed in presence which can be de-emulsified subtle changing physicochemical parameters, temperature pH.
An efficient hole extraction layer (HEL) is critical to achieve high-performance organic solar cells (OSCs). In this study, we developed a pinhole-free and HEL based on MoS2 quantum dots (QDs) combined with UV–ozone (UVO) treatment. The optophysical properties morphology of QDs their photovoltaic performance are investigated. results showed that can form homogeneous films be applied as an interfacial not only for donors shallow highest occupied molecular orbital (HOMO) but also those deep...
High-performance panchromatic organic photodetectors (OPDs) containing small molecules lead phthalocyanine (PbPc) and C70 fullerene as donor acceptor, respectively, were demonstrated. The OPDs had either a PbPc/C70 planar heterojunction (PHJ) or PbPc/PbPc:C70/C70 hybrid planar-mixed molecular (PM-HJ) structure. Both the PHJ PM-HJ devices showed broad-band response that covered wavelengths from 300 to 1100 nm. An external quantum efficiency (EQE) higher than 10% detectivity on order of 1012...