- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Minimally Invasive Surgical Techniques
- Ureteral procedures and complications
- Urinary Bladder and Prostate Research
- Renal and related cancers
- Pediatric Urology and Nephrology Studies
- Surgical Simulation and Training
- Renal and Vascular Pathologies
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Hormonal and reproductive studies
- Complement system in diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Cancer Immunotherapy and Biomarkers
- MRI in cancer diagnosis
- Anorectal Disease Treatments and Outcomes
- Renal Diseases and Glomerulopathies
Institute Mutualiste Montsouris
2016-2025
Université Paris Cité
2016-2025
Institut de Virologie
2021-2022
German Cancer Research Center
2021
Heidelberg University
2021
Délégation Paris 5
2008-2019
Sorbonne Paris Cité
2018-2019
Centre de Recherche des Cordeliers
2019
Sorbonne Université
2002-2018
Délégation Paris 6
2004-2018
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Apr 2003Laparoscopic Radical Prostatectomy: Oncological Evaluation After 1,000 Cases at Montsouris Institute B. GUILLONNEAU, H. EL-FETTOUH, BAUMERT, X. CATHELINEAU, J.D. DOUBLET, G. FROMONT, and VALLANCIEN GUILLONNEAUB. GUILLONNEAU , EL-FETTOUHH. EL-FETTOUH BAUMERTH. BAUMERT CATHELINEAUX. CATHELINEAU DOUBLETJ.D. DOUBLET FROMONTG. FROMONT VALLANCIENG. View All Author...
Purpose: The efficacy of PD-1 checkpoint blockade as adjuvant therapy in localized clear cell renal carcinoma (ccRCC) is currently unknown. identification tumor microenvironment (TME) prognostic biomarkers this setting may help define which patients could benefit from and uncover new therapeutic targets.Experimental Design: We performed multiparametric flow cytometric immunophenotypic analysis T cells isolated tissue [tumor-infiltrating lymphocytes (TIL)], adjacent non-malignant...
Clear-cell renal cell carcinoma (ccRCC) possesses an unmet medical need, particularly at the metastatic stage, when surgery is ineffective. Complement a key factor in tissue inflammation, favoring cancer progression through production of complement component 5a (C5a). However, activation pathways that generate C5a tumors remain obscure. By data mining, we identified ccRCC as type expressing concomitantly high expression components are part classical pathway. To understand how cascade...
We prospectively evaluated the morbidity, and minor major complications of laparoscopic radical prostatectomy performed by a single surgical team.Between January 28, 1998 February 2001, 567 patients 42 to 77 years old (mean age plus or minus standard deviation 63.5 +/- 6) with clinically localized prostate cancer underwent prostatectomy, including 458 (80.6%), without lymphadenectomy. Mean body mass index was 25.3 2.9 (range 17.3 37.5). American Society Anesthesiologists score 1 3 in 65%,...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jul 2002Complications Transperitoneal Laparoscopic Surgery in Urology: Review 1,311 Procedures at a Single Center G. Vallancien, X. Cathelineau, H. Baumert, J.D. Doublet, and B. Guillonneau VallancienG. Vallancien , CathelineauX. Cathelineau BaumertH. Baumert DoubletJ.D. Doublet GuillonneauB. View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64823-9AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...
We performed a nonrandomized retrospective comparison of 2 techniques for laparoscopic partial nephrectomy, that is without and with clamping the renal vessels.Between December 1997 February 2002, 28 consecutive patients underwent transperitoneal nephrectomy tumor. In group 1 (12 patients) was ultrasonic shears bipolar cautery vessels, while in (16 pedicle clamped before tumor excision. intracorporeal kidney cooling achieved by ureteral catheter connected to 4C solution. Intracorporeal...
To explore the views of experts about development and validation a robotic surgery training curriculum, how this should be implemented. An international expert panel was invited to structured session for discussion. The study mixed design, including qualitative quantitative components based on focus group interviews during European Association Urology (EAU) Robotic Section (ERUS) (2012), EAU (2013) ERUS meetings. After introduction aims, principles current status curriculum development,...
We compared a single institution experience with radical prostatectomy using pure laparoscopic technique vs robotically assisted regard to preoperative, intraoperative or postoperative parameters.From May 2003 2005 we reviewed 133 consecutive patients who underwent extraperitoneal robot and them match-paired treated approach. The were matched for age, body mass index, previous abdominopelvic surgery, American Society of Anesthesiologists score, prostate specific antigen, pathological stage...
Abstract Purpose: The diagnosis of localized prostate cancer is difficult due to a lack cancer-specific biomarkers. Many patients require repeat biopsies diagnose the disease. We investigated whether aberrant promoter hypermethylation in prostatic fluid could reliably detect cancer. Experimental Design: Urine samples were collected after massage from 95 with undergoing radical prostatectomy (63 pT1, 31 pT2, and 1 pT3) 38 control patients. Ten genes (GSTP1, RASSF1a, ECDH1, APC, DAPK, MGMT,...
No AccessJournal of UrologyAdult Urology1 Dec 2010The Learning Curve for Laparoscopic Radical Prostatectomy: An International Multicenter Study Fernando P. Secin, Caroline Savage, Claude Abbou, Alexandre de La Taille, Laurent Salomon, Jens Rassweiler, Marcel Hruza, François Rozet, Xavier Cathelineau, Gunther Janetschek, Faissal Nassar, Ingolf Turk, Alex J. Vanni, Inderbir S. Gill, Philippe Koenig, Jihad H. Kaouk, Luis Martinez Pineiro, Vito Pansadoro, Paolo Emiliozzi, Anders Bjartell, Thomas...
Abstract The complement system is a powerful and druggable innate immune component of the tumor microenvironment. Nevertheless, it challenging to elucidate exact mechanisms by which affects growth. In this study, we examined processes master regulator factor H (FH) clear cell renal carcinoma (ccRCC) lung cancer, two cancers in overactivation predicts poor prognosis. FH was present distinct cellular compartments: membranous (mb-FH) intracellular (int-FH) compartments. Int-FH resided lysosomes...
The complement system plays a complex role in cancer. In clear cell renal carcinoma (ccRCC), local production of proteins drives tumor progression, but the mechanisms by which they do this are poorly understood. We found that activation, as reflected high plasma C4d or deposits at site, was associated with poor prognosis two cohorts patients ccRCC. High expression C4-activating enzyme C1s cells three cohorts. Multivariate Cox analysis revealed prognostic value independent from deposits,...