A5022435318- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Urological Disorders and Treatments
- Renal and Vascular Pathologies
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Organ Donation and Transplantation
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Surgical Simulation and Training
- Minimally Invasive Surgical Techniques
- Urinary Bladder and Prostate Research
- Tissue Engineering and Regenerative Medicine
- Anatomy and Medical Technology
- Adrenal and Paraganglionic Tumors
- Testicular diseases and treatments
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- semigroups and automata theory
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Multiple and Secondary Primary Cancers
Saarland University
2015-2025
Universitätsklinikum des Saarlandes
2012-2024
University of Göttingen
2022-2024
Centro de Investigación Docencia y Consultoria Administrativa
2024
St.-Antonius-Hospital Gronau
2024
University Medical Center
2014-2016
KU Leuven
2016
Centre Alexandre Koyré
2016
University Hospital and Clinics
2016
Hamburg Institut (Germany)
2016
We report the cloning and characterization of a tumor-associated carbonic anhydrase (CA) that was identified in human renal cell carcinoma (RCC) by serological expression screening with autologous antibodies. The cDNA sequence predicts 354-amino acid polypeptide molecular mass 39,448 Da has features type I membrane protein. predicted includes 29-amino signal sequence, 261-amino CA domain, an additional short extracellular segment, 26-amino hydrophobic transmembrane hydrophilic C-terminal...
To explore the views of experts about development and validation a robotic surgery training curriculum, how this should be implemented. An international expert panel was invited to structured session for discussion. The study mixed design, including qualitative quantitative components based on focus group interviews during European Association Urology (EAU) Robotic Section (ERUS) (2012), EAU (2013) ERUS meetings. After introduction aims, principles current status curriculum development,...
What's known on the subject? and What does study add? There is evidence from large abdominal surgeries some open cystectomy series that multifactorial fast‐track regimens shorten postoperative convalescence without any effect morbidity mortality. Such a regimen of particular interest in combination with minimally invasive techniques, as early patient recovery demands for more rapid nutrition mobilisation schemes. The present study, single institution, reports design, application results...
Little is known regarding functional outcomes after robot-assisted radical cystectomy (RARC) and intracorporeal neobladder (ICNB) reconstruction. To report on urinary continence (UC) erectile function (EF) at 12 mo RARC ICNB reconstruction investigate predictors of these outcomes. We used data from a multi-institutional database patients who underwent for bladder cancer. The cystoprostatectomy sensu stricto followed the conventional steps. was performed physician's discretion according to...
The highest CK2 activity was found in mouse testicles and brain, followed by spleen, liver, lung, kidney heart. values were directly correlated with the protein expression level of subunits α (catalytic) β (regulatory). α′ subunit only detected brain testicles. By contrast, Northern blot analyses CK2α mRNA revealed a somewhat different picture. Here, strongest signals obtained for heart lung. In kidney, spleen mRNAs weakly detectable. For CK2α′ distribution strong observed liver case CK2β...
: Recent studies of rare cases pT3a renal cell carcinoma extending directly into the adrenal gland showed worse survival than in other and recategorization as stage pT4 was suggested. We assessed prognostic validity a diagnosis based on perirenal fat infiltration.: The records 1,794 patients with who underwent surgical resection between 1975 2000 at our institution were analyzed retrospectively. Focusing tumors, defined by infiltration, numerous clinical histopathological parameters...
Background Does the dogma of nephron sparing surgery (NSS) still stand for large renal masses? Available studies dealing with that issue are considerably biased often mixing imperative elective indications NSS and also including less malignant variants or even benign tumors. Here, we analyzed oncological long-term outcomes patients undergoing radical tumor nephrectomy (RN) non-endophytic, (≥7cm) clear cell carcinoma (ccRCC). Methods Prospectively acquired, clinical databases from two...
The purpose of this study was to investigate the effect a surgically constructed bilateral peritoneal flap (PIF) as an adjunct robot-assisted radical prostatectomy (RARP) and pelvic lymph node dissection (PLND) on incidence lymphoceles.A total 530 men with localized prostate cancer underwent RARP extended standardized PLND in prospective randomized controlled trial. In group A, PIF created by suturing margins bladder peritoneum ipsilateral endopelvic fascia at 2 points each side. B, no...
What's known on the subject? and What does study add? Lymph node dissection it's extend during robot‐assisted radical cystectomy varies based surgeon related factors. This reports outcomes of extended lymphadenectomy experience in both academic private practice settings. Objective To evaluate incidence of, predictors for, lymph ( LND ) patients undergoing RARC for bladder cancer, as is critical treatment cancer but role minimally invasive surgery has not been well‐defined a...
To compare, in a retrospective observational cohort study, the efficacy, tolerability and safety of propiverine oxybutynin children with urge incontinence (UI) due to overactive bladder.Medical records were scrutinized for UI. As primary efficacy outcome variable achievement continence after treatment doses or was assessed. Weekly UI episodes daily voiding frequency evaluated as secondary outcomes. Tolerability by rate adverse events, drug reactions caused antimuscarinics premature...
Urge incontinence and voiding postponement are common subtypes of daytime wetting in children. We analyzed health related quality life for children with urge postponement, healthy controls at 2 centers.We examined a total 49 consecutive 5 to 13 years old who presented (22) or (27), 32 matched age sex. Health overall were measured generic questionnaires, self-esteem was the Piers-Harris questionnaire.Health significantly reduced parent rating but not child incontinent vs control group (total...
Objective To evaluate surgeons adherence to current clinical practice, with the available evidence, for robot‐assisted radical prostatectomy ( RARP ) and offer a baseline assessment measure impact of P asadena recommendations. Recently, E uropean A ssociation U rology R obotic S ection ERUS supported C onsensus onference on best practices in . Subjects Methods This survey was performed J anuary 2012. specific questionnaire sent, by e‐mail, 145 robotic who were included mailing‐list members...
Partial nephrectomy (PN) preserves renal function and has become the standard approach for T1a cell carcinoma (RCC). However, there is still an ongoing debate as to which patients will actually derive greater benefit from partial than radical (RN). The aim of this study was retrospectively evaluate impact type surgery on overall survival (OS) in with localized RCC. Renal performed 4326 RCC (pT ≤ 3a N/M0) at six German tertiary care centers 1980 2010: RN 2955 cases (68.3%), elective (ePN)...