- Occupational and environmental lung diseases
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Soft tissue tumor case studies
- Renal and related cancers
- Radiation Dose and Imaging
- Occupational exposure and asthma
- Genetic factors in colorectal cancer
- Eosinophilic Disorders and Syndromes
- Carcinogens and Genotoxicity Assessment
- Hormonal and reproductive studies
- Lymphoma Diagnosis and Treatment
- Cellular Mechanics and Interactions
- Tissue Engineering and Regenerative Medicine
- Cancer Cells and Metastasis
- Lung Cancer Research Studies
- Prostate Cancer Treatment and Research
- Metastasis and carcinoma case studies
- Cancer Research and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Neuroblastoma Research and Treatments
Flinders Medical Centre
2009-2020
Flinders University
2010-2020
South Australia Pathology
2010-2020
Duke University
2016
University of Vermont
2006-2013
University of Vermont Medical Center
2006-2013
Royal Brompton & Harefield NHS Foundation Trust
2013
Imperial College London
2013
Queen Elizabeth II Medical Centre
1979-2013
University of California, San Francisco
2013
The new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification provides, first time, standardized terminology cancer diagnosis in small biopsies and cytology; this was not primarily addressed by previous World Health Organization classifications. Until recently there have been no therapeutic implications to further NSCLC, so little attention has given distinction squamous cell carcinoma tissue samples....
Asbestosis is defined as diffuse pulmonary fibrosis caused by the inhalation of excessive amounts asbestos fibers. Pathologically, both a particular pattern and evidence excess in lungs must be present. Clinically, disease usually progresses slowly, with typical latent period more than 20 years from first exposure to onset symptoms.IDIOPATHIC PULMONARY FIBROSIS: The asbestosis interstitial has basal subpleural distribution, similar that seen idiopathic fibrosis, which principal differential...
A new lung adenocarcinoma classification has been published by the International Association for Study of Lung Cancer, American Thoracic Society, and European Respiratory Society. This is needed to provide uniform terminology diagnostic criteria, most especially bronchioloalveolar carcinoma. It was developed an international core panel experts representing all 3 societies with oncologists/pulmonologists, pathologists, radiologists, molecular biologists, thoracic surgeons.This summary focuses...
IntroductionSurvival after extrapleural pneumonectomy (EPP) is variable in patients with malignant pleural mesothelioma (MPM), and there are no validated prognostic factors that could be used preoperatively. We investigated the calretinin D2-40 expression neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation as potential preoperative factors.MethodsConsecutive who underwent EPP were included this retrospective study. Potential such age, gender, histological subtype,...
Malignant mesothelioma (MM) is an aggressive malignancy of the serosal membranes. Early diagnosis and accurate prognostication remain problematic. BAP1 a tumour suppressor gene commonly mutated in MM. Germline mutation has been associated with early onset less disease compared sporadic Sporadic mutations are common improved survival MM, contrary to other malignancies. This study investigated prognostic role matched cytology surgical specimens aimed investigate association between established...
Abstract Asbestosis is defined as diffuse pulmonary fibrosis caused by the inhalation of excessive amounts asbestos fibers. Pathologically, both a particular pattern and evidence excess in lungs must be present. Clinically, disease usually progresses slowly, with typical latent period more than 20 years from first exposure to onset symptoms. Differential Diagnosis: Idiopathic Pulmonary Fibrosis The asbestosis interstitial has basal subpleural distribution, similar that seen idiopathic...
A 72-year-old woman was diagnosed with uveal melanoma, peritoneal mesothelioma and a primary biliary tract adenocarcinoma. She had strong family history of as well other malignancies including renal cell carcinoma. The recently described BAP1 hereditary cancer predisposition syndrome suspected, but immunohistochemical labeling not conclusive. Genetic testing confirmed novel unusual germline mutation in the ubiquitin hydrolase domain gene (p.Tyr173Cys) patient syndrome. This case demonstrates...