- Medication Adherence and Compliance
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Health Systems, Economic Evaluations, Quality of Life
- Pelvic and Acetabular Injuries
- Hernia repair and management
- Pharmaceutical Economics and Policy
- Adolescent and Pediatric Healthcare
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Acute Kidney Injury Research
- Diabetes Management and Research
- Diabetes Management and Education
- Multiple Sclerosis Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Appendicitis Diagnosis and Management
- Economic and Financial Impacts of Cancer
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Entomopathogenic Microorganisms in Pest Control
- Patient Satisfaction in Healthcare
- Advanced Breast Cancer Therapies
- Colorectal Cancer Treatments and Studies
- Social Media in Health Education
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
National Institute for Health Research
2024
University of Birmingham
2020-2024
T1D Exchange
2023-2024
Vanderbilt Health
2023
Vanderbilt University Medical Center
2019-2023
Lipscomb University
2021
Virginia Commonwealth University
2016-2017
Nnamdi Azikiwe University
2017
Disease-modifying therapy (DMT) delays disease progression and improves quality of life for patients with multiple sclerosis (MS), but adherence to DMT is often suboptimal. Vanderbilt Specialty Pharmacy (VSP) embeds pharmacists within an outpatient MS clinic provide medication management address barriers adherence.We evaluated rates predictors among at integrated specialty pharmacy.We included who filled ≥3 prescriptions from VSP during the study period. Adherence was defined as possession...
Introduction Fear of hypoglycemia (FoH) affects quality life, emotional well-being, and diabetes management among people with type 1 (PwT1D). American Diabetes Association’s (ADA) guidelines recommend assessing FoH in clinical practice. However, existing measures are commonly used research not In this study, prevalence was assessed PwT1D using a newly developed screener for practice; its association established outcomes also determined. addition, healthcare providers’ (HCPs) perspectives on...
Medical and research professionals who discuss clinical trials studies with potential participants face an often daunting challenge, particularly when recruiting from minority underserved populations. This study reports on findings a focus group of 63 coordinators, nurses, professional recruiters, other in Indianapolis, IN Miami, FL work to recruit These discussed the importance creating sense connection as part recruitment retention process. Building relationship, however fleeting, involved...
BACKGROUND: Disease-modifying anti-rheumatic drugs (DMARDs) improve symptoms and delay progression of rheumatoid arthritis (RA), but adherence is often sub-optimal many patients change medication (either "switching" to a with different mechanism action or "cycling" the same action) during first year therapy. Some integrated health-system specialty pharmacies embed pharmacists in clinics help access adhere medication. OBJECTIVE: This study assessed DMARD switching, cycling, adherence,...
Abstract Background Acutely symptomatic abdominal wall and groin hernias are a common reason for acute surgical hospital admissions. There limited data to guide the treatment of these patients. This study aimed assess outcomes emergency hernia surgery identify management strategies, improve care high-risk Methods A 20-week, national multicentre, collaborative, prospective cohort (NCT04197271) recruited adults with acutely across UK. Data on patient characteristics, inpatient management,...
Abstract Purpose The purpose of this study is to obtain insight into providers’ satisfaction with services offered by health-system integrated specialty pharmacies and determine whether perceptions under an model differ from external pharmacy services. Methods A multi-site, cross-sectional, online survey clinic healthcare providers at 10 academic health systems was conducted. questionnaire developed members the Vizient Specialty Pharmacy Outcomes Benchmarking Workgroup pretested 3 pilot...
Screening for islet-specific autoantibodies can identify individuals at risk type 1 diabetes (T1D). Despite calls increased nationwide autoantibody screening efforts, it is unclear how many have participated in among people who may benefit from it. Moreover, knowledge and perceptions of real-world samples are not well understood.
The effectiveness of specialty medications in complicated clinical conditions depends on adherence to therapy. However, pose unique barriers adherence. This study aims determine whether pharmacist interventions improve medication is a single-center, pragmatic, randomized controlled trial ongoing since 10 May 2019 at an integrated health system pharmacy. evaluates usual care compared with plus patient-tailored interventions. Study design and procedures were informed by focus groups patients...
The development of a tool to measure medication safety, therapeutic efficacy, and other quality outcomes in patients receiving self-injectable biologic therapy for the management inflammatory bowel disease (IBD) at health-system specialty pharmacy is described.Through collaborative initiative by pharmacists, gastro-enterologists, representatives benefit manager pharmaceutical company, set clinical measures was developed. are intended use assessing patient status, treatment healthcare...
BACKGROUND: Dalfampridine improves walking speed in patients with multiple sclerosis (MS), but accessing specialty medications such as dalfampridine can be hindered by insurance restrictions, high costs, and limited distribution networks (LDNs) imposed manufacturers. Some integrated health-systems pharmacies (HSSPs) embed pharmacists clinics dispense from their internal if included within the LDN. OBJECTIVE: To assess access to at an HSSP before after gaining admission METHODS: This study...
Abstract Introduction Acutely symptomatic abdominal wall and groin hernias (ASH) are a common acute surgical presentation. There limited data to guide decisions related repair technique use of antibiotics, which can be driven by increased risk site infection (SSI) in this group. This study aims report rates SSI following ASH explore the patient-reported outcome measure reporting setting. Methods An 18-week, UK-based, multicentre prospective cohort (NCT04197271) recruited adults with ASH....
Integrated health-system specialty pharmacies (IHSSP) have shown high medication access, adherence, and provider satisfaction. The goal of this study was to explore healthcare providers’ experiences with medications distributed via Limited Distribution Networks (LDN) that do not include IHSSPs. We investigated perceived impact LDNs on clinic workflow, clinical practice, patient outcomes. Interviews focus groups were conducted fourteen providers from four outpatient clinics at an academic...
Breast cancer risk is significantly reduced by improvements in lifestyle factors such as physical activity. Previous work suggests personal experiences false positive mammography or family history of breast may influence these health behaviors. Surveys were distributed to women aged 40-75 who had received a negative mammogram from an academic hospital Virginia 2015. Measures assessed worry and perceived risk, awareness factors, cancer, experience, readiness change collected 106 women. The...
Background: Collaborative pharmacist practice agreements (CPPAs) advance the role of pharmacists by granting prescriptive authority without direct oversight from participating physicians. Objective: To assess quantity prescriptions authorized and frequency types interventions performed under a CPPA in an outpatient renal transplant clinic. Practice description: Clinical clinic began prescribing medications March 2017. innovation: Under CPPA, perform to improve medication management. After...
Background: Sorafenib and regorafenib are oral multikinase inhibitors used to treat some cancers, but adverse events for both drugs common often cause patients discontinue therapy or reduce their dose within several months of initiating therapy. Pharmacists have the potential prevent discontinuation by closely monitoring addressing patients’ reactions. Aims: To assess whether a pharmacist-initiated tailored intervention reduced patient discontinuations reductions due reactions from sorafenib...
Health-system specialty pharmacies (HSSPs) provide high-quality, efficient, and collaborative care to patients receiving therapy. Despite proven benefits of the integrated model, manufacturer payer restrictions challenge viability utility HSSPs. Vanderbilt Specialty Pharmacy developed a health outcomes research program measure communicate value this drive improvement in patient delivery, advocate for recognition HSSP pharmacists' role care. The purpose descriptive report is describe...
Endophytic fungi are the most promising source for new drugs to combat problem of antimicrobial resistance. Twelve fungal endophytes were isolated from leaves and stems Azadirachta indica, Psiduim guajava, Newbouldia laevis Agerantum conyzoides collected southeastern Nigeria using standard methods. Solid state fermentation carried out on rice media 21 days at 22 °C secondary metabolites extracted ethyl acetate. The extracts tested antiplasmodial activity in vivo against Plasmodium berghei...
Background: Barriers to accessing oral oncolytic therapy include insurance authorization, high copays and limited distribution drug (LDD) networks. In September 2015, a pharmacist joined an outpatient hematology clinic facilitate timeliness of medications (for which the pharmacy has access) dispensed by Vanderbilt Specialty Pharmacy (VSP). The scope expanded manage non-VSP in June 2016. Aims: Compare access time between drugs VSP vs. medications, test whether patient agents reduced after...