Irena Jonauskiené

ORCID: 0000-0003-3999-704X
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About
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Research Areas
  • Pharmacological Effects of Natural Compounds
  • Animal health and immunology
  • Pharmacological Effects of Medicinal Plants
  • Toxin Mechanisms and Immunotoxins
  • Fungal Biology and Applications
  • Natural product bioactivities and synthesis
  • Polysaccharides and Plant Cell Walls
  • Respiratory viral infections research
  • Natural Compounds in Disease Treatment
  • Animal Virus Infections Studies
  • Humic Substances and Bio-Organic Studies
  • Ginseng Biological Effects and Applications
  • Virology and Viral Diseases
  • Viral gastroenteritis research and epidemiology
  • Influenza Virus Research Studies
  • Rheumatoid Arthritis Research and Therapies
  • Transgenic Plants and Applications
  • Cardiovascular Disease and Adiposity
  • Cardiomyopathy and Myosin Studies
  • Diabetes and associated disorders
  • Cardiac Imaging and Diagnostics
  • Synthesis and bioactivity of alkaloids
  • Rabbits: Nutrition, Reproduction, Health
  • Drug Transport and Resistance Mechanisms
  • Polysaccharides Composition and Applications

State Research Institute Centre for Innovative Medicine
2015-2021

KU Leuven
2015

Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"
2015

Vilnius University
2008

Uppsala University
2004

The purpose of the present study was to examine anti-arthritic and antioxidant effects herbal active organic ingredient complex (EM 1201) in rats with experimental adjuvant arthritis (AA).AA induced 30 male Wistar by intradermal injection complete Freund's into left hind paw. course disease response treatment EM 1201 diclofenac, parameters including body weight, joint swelling, blood indices pro-/antioxidant status serum, histology joints liver, were investigated.Preparation showed...

10.1016/j.medici.2015.11.002 article EN cc-by-nc-nd Medicina 2015-01-01

$\beta$-Glucan is a natural polymer, which widely studied due to its multiple immunomodulatory properties. In addition, recent findings indicate potent antitumor properties of $\beta$-glucan. Saccharomyces cerevisiae, baker's yeast, one the commonly used sources $\beta$-1,3-glucan. The aim this work was investigate S. cerevisiae $\beta$-glucan activity against cancer cells.In our experiments, BALB/c mice were fed with insoluble whole particles, and then their blood collected for experiments....

10.3906/biy-1411-53 article EN TURKISH JOURNAL OF BIOLOGY 2015-01-01

The present study aimed to investigate the antiinflammatory effects of 2 herbal extracts (CDS and CDSM) in rats with experimental adjuvant arthritis (AA). Joint swelling, development polyarthritis, blood indices, pro/antioxidant activity, proinflammatory cytokine IL-17 serum, as well liver paw histopathology histochemistry, were assessed. Oral injections showed an effect analogous that diclofenac (DF), improved indices suppressed level IL-17, significantly diminished joint histological...

10.3906/vet-1704-16 article EN TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES 2017-01-01

<p>The aim of the current study was to evaluate immunostimulatory activity 10 different herbal extracts from <em>Vitex agnus-castus</em>, <em>Vinca major, Aloe arborescens </em>and polyherbal product containing <em>Sambucus nigra</em>, <em>Primula</em><em> versis</em>, <em>Pinus alba</em>, <em>Gentiana lutea</em>, <em>Cetraria islandica</em>, <em>Eucaliptus globulus</em>,...

10.4995/wrs.2016.4139 article EN World Rabbit Science 2016-12-28

Purpose: To investigate the relationship between two measures of regional myocardial workload (RMW): glucose metabolism, assessed by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) and LV pressure-strain loop area.Both were evaluated in a chronic rapid pacing animal model dilated cardiomyopathy (DCM) LBBB-like mechanical dyssynchrony.Methods: Nine sheep subjected to RV (180 bpm), developing dilatation asymetric remodelling, with ventricular activation.After 8 weeks all...

10.1093/ehjci/jev261 article EN European Heart Journal - Cardiovascular Imaging 2015-12-01

Objetivo. El objetivo de la presente investigación fue evaluar actividad inmunoestimulante extractos hierbas Allium sativum, Aloe arborescens y óxido germanio. Materiales métodos. Las codornices se inmunizaron tres veces por vía oral con albúmina suero bovino (BSA) en combinación los vegetales crudos sustancia inorgánica antes indicada. Los anticuerpos IgA específicos BSA saliva IgY yema huevo analizaron mediante ELISA. Resultados. Se encontró que las aves tratadas sativum o germanio tenían...

10.21897/rmvz.1372 article ES cc-by-sa Revista Mvz Córdoba 2018-09-01

The present study evaluated the therapeutic benefits of complex herbal preparation named CBMDS, consisting turmeric (Curcuma longa), Boswellia (Boswellia serrata), Methylsulphonylmethane, Devil’s Claw (Harpagophytum procumbens) and Silymarin, using it in combination with methotrexate, order to suppress adjuvant arthritis rats, attenuate methotrexate-induced liver damage. Adjuvant was induced 28 rats by a single subplantar injection complete Freund’s (0.1 mL) into left hind paw. animals were...

10.24099/vet.arhiv.0973 article EN Veterinarski arhiv 2021-09-15

Many active anti-arthritic natural substances are revealed into the past years. The aim of study was to assess combined efficacy methylsulfonylmethane (MSM) with thiocolchicoside (Th) (compound MTh) and MSM alone against adjuvant-induced arthritis (AA) in rats. In first experiment 30 rats second - 21 ratswere randomly divided 6 groups: I gr. AA + (77 mg/kg), II V diclofenac (DF), III VI control groups without treatment, IV MTh (38 mg/kg). DF (1 mg/kg) both experiments used as a reference...

10.12681/jhvms.20862 article EN cc-by-nc Journal of the Hellenic Veterinary Medical Society 2019-07-12
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