- Advanced Radiotherapy Techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear Physics and Applications
- Radiation Therapy and Dosimetry
- Radiation Effects and Dosimetry
- Cardiac Imaging and Diagnostics
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Bone health and osteoporosis research
- Bone health and treatments
- Radiation Dose and Imaging
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Treatment and Pharmacology
- Cardiac, Anesthesia and Surgical Outcomes
- Chemical Thermodynamics and Molecular Structure
- Amphibian and Reptile Biology
- PARP inhibition in cancer therapy
- X-ray Diffraction in Crystallography
- Cardiovascular Health and Disease Prevention
- Radioactivity and Radon Measurements
- Aortic aneurysm repair treatments
- Radiation Effects in Electronics
- Lanthanide and Transition Metal Complexes
- Advanced MRI Techniques and Applications
- Advanced X-ray Imaging Techniques
Universidade do Estado do Rio de Janeiro
2018-2024
Universidade Federal do Rio de Janeiro
2009-2018
Purpose For x‐ray beams in the low and medium energy range, reference dosimetry is established terms of air kerma. Fricke has shown great potential absolute measurements absorbed dose to water for high‐energy ranges. Therefore, main purpose this work was compare medium‐energy obtained through with that from kerma rate. Methods To determine using dosimetry, polyethylene bags methodology chosen. solution irradiated at four different beam qualities. The values were compared those standard...
Radiation damage is an important aspect to be considered when analysing biological samples with X-ray techniques as it can induce chemical and structural changes in the specimens. This work aims provide new insights into soft induced radiation of complete sample, including not only tissue itself but also substrate embedding medium, fixation procedure. Sample preparation handling involves unavoidable interaction sample matrix could play role radiation-damage mechanism. To understand influence...
In the last decades, studies showed that exposure to low doses of ionizing radiation body could sense and activate cell signaling pathways needed respond any induced cellular damage. This procedure reduces killing compared with a single dose high dose. Damage vasculature can affect function most organs by restricting blood flow oxygen tissues; however, heart brain are main concern. The precise relationship between long-term health effects low-dose exposures remain poorly understood....
Abstract Amphibians are models for studying applied ecological issues such as habitat loss, pollution, disease, and global climate change due to their sensitivity vulnerability changes in the environment. Developmental series of amphibians informative about biology, X-ray based 3D reconstruction holds promise quantifying morphological during growth—some with a direct impact on possibility an experimental investigation several topics listed above. However, resolution discrimination soft...
Data from Global Cancer Statistics show that breast cancer (BC) is the most common type of among women, leading number deaths caused by cancer. The developments in diagnosis and treatment techniques for BC, including chemotherapy and/or radiotherapy, increased survival rates this One late complication induced BC cardiotoxicity. This term comprises different cardiotoxic side effects, which include blood pressure alterations, myocardial ischemia, congestive heart failure other damages. study...
Purpose The Fricke dosimeter has been shown to be a viable option as an absorbed dose standard. This work aims provide the distribution in irradiator container during blood irradiation using dosimetry. Methods Measurements were performed Gammacell Elan 3000 at Hemocenter Rio de Janeiro, Brazil. A specific phantom was constructed and patented by authors perform these measurements. solution prepared according international protocols, polyethylene bags filled with (n = 19) spatially distributed...
Breast cancer (BC) is the most frequent and leading cause of cancer-related mortality in women. The treatment techniques for BC include chemotherapy (CT) and/or radiotherapy (RT) can modify elementary cell matrix by calcificating tissues due to biological morphological changes. Also, treatments induce cardiotoxicity it important understand mechanisms involved order prevent this late effect treated breast patients. high incidence cardiovascular patients partially credited increased intimal...
Hypertension is one of the major public health problems worldwide. It can cause severely alterations in artery structure and function such as vascular remodeling. Angiotensin II (Ang II) has been linked to dysfunction. shown that blockade Ang type 1 receptor with an blocker (ARBs) may reverse pathology independently blood pressure lowering. There therefore a special interest establishing whether antihypertensive treatment correct part or completely structural functional arteries. Several...
In recent years, new techniques have been developed for the analysis of bone matrix. Two most common technologies that make use X‐rays are X‐ray microfluorescence (μXRF) and absorption microtomography (μCT). μXRF is a powerful analytical tool spectroscopic determination almost all elements ( Z > 13) present in sample. μCT nondestructive technique, which can be used to create cross sections complex objects. this work, both were applied bones evaluate possible structural elemental...
Abstract Radiotherapy (RT) plays a pivotal role in the treatment of breast cancer (BC) and various thoracic malignancies. Radiation induced heart disease (RIHD) is one such long term toxicity which can offset improvement specific mortality. Long normal tissue becoming bigger concern, as early diagnosis these cancers has led to patients surviving longer. Our research group on Physics applied biomedical sciences been investigating side effects BC (RT chemotherapy) for more than ten years. The...
The dosimetry of cosmic radiation outside Earth's atmosphere is a significant challenge due to the high complexity fields encountered in Low Earth Orbit (LEO) and interplanetary space, addition constraints imposed by instrument spaceflight. Fricke dosimeter water-based (96% mass) chemical system that offers potential measure absorbed dose water an arbitrary geometry, for doses up 400 Gy, different energy spectra. LCR/UERJ was part Cubes Space project. main goal this work obtain at altitudes...