- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- COVID-19 diagnosis using AI
- Nanoplatforms for cancer theranostics
- Gout, Hyperuricemia, Uric Acid
- Metabolism and Genetic Disorders
- Advanced X-ray and CT Imaging
- Neonatal Health and Biochemistry
- Analytical Chemistry and Sensors
- Artificial Intelligence in Healthcare and Education
- Machine Learning in Healthcare
- Lung Cancer Diagnosis and Treatment
- Photodynamic Therapy Research Studies
- Acute Ischemic Stroke Management
- Pediatric Hepatobiliary Diseases and Treatments
- Meningioma and schwannoma management
- RNA Interference and Gene Delivery
- Nutrition and Health in Aging
- COVID-19 Clinical Research Studies
- Radiation Dose and Imaging
- Neurofibromatosis and Schwannoma Cases
- Cerebral Venous Sinus Thrombosis
- Cerebrovascular and Carotid Artery Diseases
First Affiliated Hospital of Jinan University
2015-2025
Imaging Center
2022
UNSW Sydney
2020
Memorial Sloan Kettering Cancer Center
2019
Jinan University
2012-2019
Institut Pasteur
2019
Southern Medical University
2019
Anhui Provincial Center for Disease Control and Prevention
2019
Umeå University
2019
Zero to Three
2016
COVID-19 has overwhelmed health systems worldwide. It is important to identify severe cases as early possible, such that resources can be mobilized and treatment escalated.
Patients with diabetes mellitus, diabetic nephropathy (DN) and healthy donor were analyzed to test whether the early DN patients can be detected using both blood oxygenation level dependent (BOLD) diffusion tensor imaging.This study was approved by Ethics Committee of our hospital. MR images acquired on a 3.0-Tesla system (Discovery MR750, General Electric, Milwaukee, WI). 30 divided into NAU (normal mildly increased albuminuria, N = 15) MAU (moderately group based absence or presence...
Purpose To investigate the potential of intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) in assessment renal fibrosis using a rat model unilateral ureteral obstruction (UUO). Materials and Methods Thirty‐two UUO rats were created by complete ligation left ureter. IVIM was performed on clinical 3.0T whole‐body MRI scanner before (day 0) days 1, 3, 5, 7 after ligation, followed histological analysis to examine α‐smooth muscle actin (α‐SMA) expression tubulointerstitial...
Purpose To evaluate the diagnostic value of intravoxel incoherent motion imaging (IVIM) in differentiating metastatic and nonmetastatic lymph nodes patients with rectal carcinoma. Materials Methods In all, 68 histologically proven carcinoma underwent an IVIM sequence (b = 0, 25, 50, 75, 100, 150, 200, 400, 600, 800, 1000, 1200, 1500, 2000 s/mm 2 ) on a 3.0T MRI scanner. The parameters (D, D*, f, apparent diffusion coefficient [ADC] values) were measured calculated. Receiver‐operating...
Colorectal cancer (CRC) is the third most common malignancy worldwide, and lymph node metastasis considered to be a risk factor for local recurrence poor prognosis in colorectal cancer. However, there remains lack of reliable non-invasive biomarkers identify status CRC patients preoperatively. The purpose this study was explore ability dual-energy computed tomography (DECT) differentiate metastatic from non-metastatic nodes cancer.Seventy-one with primary underwent contrast-enhanced imaging...
Some chemotherapeutics have been shown to induce both the release of damage-associated molecular patterns (DAMPs) and production type I interferon (IFN-I), leading immunogenic cell death (ICD). However, standard chemotherapy drug for glioma, temozolomide (TMZ), cannot ICD as it activate IFN-I signaling. Moreover, inefficient delivery immunostimulants across blood-brain barrier (BBB) is main obstacle overcome in order local immune responses brain.
Obstructed nephropathy is a common complication of several disease processes. Accurate evaluation the functional status obstructed kidney important to achieve good outcome. The purpose this study was investigate renal cortical and medullary perfusion changes associated with unilateral ureteral obstruction (UUO) using whole-organ imaging 320-detector row computed tomography (CT).Sixty-four patients UUO underwent CT imaging. Patients were divided into 3 groups, mild, moderate, severe, based on...
To evaluate predictive values of body composition parameters measured from preoperative CT/MRIs for postoperative complications after laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (LRYGB) in patients with obesity.In this retrospective case-control study, performing abdominal within one month before developing 30-day bariatric procedures were matched age, sex, type surgery without (1/3 ratio, respectively). Complications determined by documentation the medical record. Two...
Biallelic mutations of the SLC25A13 gene result in citrin deficiency (CD) humans. Neonatal intrahepatic cholestasis caused by (NICCD) is major CD phenotype pediatrics; however, knowledge on its genotypic and phenotypic characteristics remains limited. The present study aimed to explore novel molecular clinical CD. An infant suspected have NICCD as well her parents were enrolled research subjects. investigated using various methods, including cDNA cloning sequencing. pathogenicity a mutation...
Abstract Automatic severity assessment and progression prediction can facilitate admission, triage, referral of COVID-19 patients. This study aims to explore the potential use lung lesion features in management COVID-19, based on assumption that may carry important diagnostic prognostic information for quantifying infection forecasting disease progression. A novel LesionEncoder framework is proposed detect lesions chest CT scans encode automatic prediction. The consists a U-Net module...
Automatic severity assessment and progression prediction can facilitate admission, triage, referral of COVID-19 patients. This study aims to explore the potential use lung lesion features in management COVID-19, based on assumption that may carry important diagnostic prognostic information for quantifying infection forecasting disease progression. A novel LesionEncoder framework is proposed detect lesions chest CT scans encode automatic prediction. The consists a U-Net module detecting...
To determine the morphological changes of intracranial arteries and whole-brain perfusion in undetermined isolated vertigo (UIV) patients using 320-detector row computed tomography (CT).A total 150 who underwent CT angiography (CTA) (CTP) imaging were divided into UIV group benign paroxysmal positional (BPPV) group. Sixty individuals with sex- age-matched without cerebral diseases served as control. The arteries, parameters vascular risk factors (VRFs) analyzed, calculated compared.In...
Background Hyperuricemia is an independent risk factor for onset and progression of kidney disease. However, there remains a lack reliable noninvasive biomarker to identify monitor the changes renal function in patients with hyperuricemia. Purpose To assess utility intravoxel incoherent motion (IVIM) parameters identifying early Study Type Retrospective case–control study. Population Eighty‐four male participants, including asymptomatic hyperuricemia (AH, 27 cases), gouty arthritis (GA, 31...
Objective: To investigate the velocity and extent of cortical venous filling (CVF) its association with clinical manifestations in patients severe stenosis or occlusion middle cerebral artery (MCA) using dynamic computed tomography angiography (CTA). Methods: Fifty-eight (36 symptomatic 22 asymptomatic) unilateral (≥70%) MCA M1 segment who underwent CTA were included. Collateral status, antegrade flow, CVF each patient observed CTA. Three types veins selected to observe CVF, absence (CVF-)...