A5025166754- Neurological Disorders and Treatments
- COVID-19 Clinical Research Studies
- Neurological Disease Mechanisms and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiovascular and exercise physiology
- SARS-CoV-2 and COVID-19 Research
- Healthcare Systems and Public Health
- Human Health and Disease
- Science, Research, and Medicine
- Sleep and Wakefulness Research
- Health and Medical Research Impacts
- Respiratory Support and Mechanisms
- Economic Sanctions and International Relations
- Long-Term Effects of COVID-19
- Exercise and Physiological Responses
- Spaceflight effects on biology
- Neuroinflammation and Neurodegeneration Mechanisms
- Memory and Neural Mechanisms
- Chemical and Physical Studies
- Neuroscience and Neuropharmacology Research
- Physical Education and Training Studies
- Hair Growth and Disorders
- Cardiac Arrest and Resuscitation
- Biochemical effects in animals
- Alcoholism and Thiamine Deficiency
S. M. Kirov Military Medical Academy
2014-2023
Russian Academy of Natural Sciences
2020
Federal Medical-Biological Agency
2020
In 2020 the whole world was faced with an epidemiological outbreak caused by a new coronavirus SARS-CoV-2. The information available to date suggests that newly isolated SARS-CoV-2 should be assigned superantigens, main manifestations of which, as it is known, are suppression nonspecific resistance factors and innate immunity mechanisms associated formation systemic inflammatory response in form cytokine storm pathological activation phagocytes lung tissue its alteration subsequent fibrosis....
The essence of the preconditioning effect is activation urgent defense mechanisms adaptation as a result short episode weak, non-damaging hypoxic or ischemic exposure, which contributes to an increase in tolerance subsequent delayed, more severe exposure hypoxia ischemia. Aim study was assess literature data on possibility using method remote (RIP) non-pharmacological for correcting physical performance. Material and methods. In Scopus, PubMed eLibrary databases, selection analysis modern...
Atrophic scars are a complex problem, covering huge number of patients with striae gravidarum, acne, atrophic surgical scars, and due to hypercortisolism other metabolic disorders. Taking into account patients’ social status (pregnant women, adolescents, people chronic hormonal disorders), our goal was systematize the literature data on least invasive treatment modality – scar therapy inorganic gels identify new chemical classes potential anti-scar activity.
 When summarizing research...
Рассмотрены особенности развития адаптационных процессов организма при деятельности человека в экстремальных условиях. Представлены современные средства коррекции работоспособности различных видах деятельности. Отмечены основные подходы к применению фармакологических средств для сохранения и повышения условиях Определены перспективные направления разработки человека. We consider characteristics of human body adaptation under extreme conditions. Modern means influencing performance in various...
Introduction. From 1960 to 2018, 282 people were enrolled in cosmonaut groups the USSR and Russia. Extreme special training working conditions could lead health disorders, which may be reflected causes rates of mortality future. The goal this work is study two cohorts cosmonauts: those with without spaceflight experience. aim research astronauts who have made did not fly into space. Methods. A cohort 263 male cosmonauts was conducted, 118 experience formed 1, 145 it - 2. follow-up period 59...
Today, there are personal protective equipment, which due to their weight and size characteristics design features can aggravate professional activity. This is characterized by an increase in the load on several major systems of employee's body, including cardiorespiratory system, cause development occupational pathology. The study functions system humans process his work important task biomedical tests such as PPE, aggravating activities future means individual protection from heavy labor...
Представлены сведения об особенностях механизма действия, клинической эффективности и побочных эффектов психостимуляторов первого, второго третьего поколений. Анализ сложной нейрофизиологической биохимической природы феномена психостимуляции предполагает вовлеченность в эффект различных нейромедиаторных нейромодуляторных механизмов, что было реализовано полной мере при создании комбинированных психостимулирующих соединений, опосредующих психоактивирующие эффекты своих активных компонентов...
The study investigated the dynamics of class G immunoglobulins to severe acute respiratory syndrome-2 coronavirus in blood serum convalescents who had a new infection for 6 months after polymerase chain reaction conversion. Among most common symptoms, 30 (73.8%) an increase body temperature 38C, 32 (83.3%) asthenia, 21 (59.5%) cough, 29 perversion or loss sense smell, pain, and throat discomfort. duration symptoms varied from 34 days weeks. Within month end disease period, 8 (20%) patients...
Previous publications reported the use of remote ischemic preconditioning (rIPC) as a non-drug method for increasing physical performance. However, data are contradictory nature. Aim: to evaluate potential rIPC performance laboratory animals. The study was performed on 72 white outbred male rats. An assessment carried out using modified Porsolt test. hind limbs non-anesthetized animals were subjected preconditioning. results single and course (during 5 days) application evaluated. A increased...
Research into cardiorespiratory responses to prolonged hypoxia (more than 60 minutes) is of particular interest in terms elucidating adaptive mechanisms under the conditions oxygen deficiency. Aim: identify parameters system relative rest most sensitive and determine optimal time interval for a hypoxic test. Experiments were carried out normobaric complex, which respiratory gas created corresponding partial pressure at altitudes 3500 4500 m. Cardiorespiratory evaluated using MetaLyzer 3B...
Introduction. Currently, there is an increasing need for the study and development of World Ocean, including purpose laying deep-water pipelines, searching new sources minerals, etc. The performance special tasks by divers at great depths has its own characteristics. high cost error, harmful working conditions - all this dictate continuous receipt analysis scientific material on preservation promotion health, ensuring their longevity, as well adaptation to nature professional activity in...
A number of clinical studies demonstrate that individual characteristics such as stress tolerance and cognitive ability can be considered not only diagnostic variables but also risk factors for severe cerebral hypoperfusion. The aim the study was to identify typological features effect physical activity on behavioral reactions rats during Material methods. Cerebral hypoperfusion modeled by bilateral carotid artery ligation. involved 280 rats, divided into equal subgroups, according sex,...
Currently, the procedure for conducting clinical trials and military is regulated by a number of regulatory documents ranging from Federal laws to local orders medical organizations. The article analyzes Russian Federation in relation with participation personnel. It noted that legal status volunteer (military personnel) when research full-scale conditions not fixed. In addition, case involvement personnel as volunteers, it should be borne mind serviceman has right engage scientific,...