Jianzhong Zhang

ORCID: 0000-0003-4019-5845
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About
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Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • Lower Extremity Biomechanics and Pathologies
  • Urinary Bladder and Prostate Research
  • Foot and Ankle Surgery
  • Tendon Structure and Treatment
  • Renal cell carcinoma treatment
  • Urinary and Genital Oncology Studies
  • Pelvic floor disorders treatments
  • Anorectal Disease Treatments and Outcomes
  • Renal and Vascular Pathologies
  • Aortic aneurysm repair treatments
  • Sexual function and dysfunction studies
  • Pain Mechanisms and Treatments
  • Renal and related cancers
  • Neurosurgical Procedures and Complications
  • Proteoglycans and glycosaminoglycans research
  • Abdominal vascular conditions and treatments
  • Protease and Inhibitor Mechanisms
  • Anesthesia and Pain Management
  • Reproductive Health and Technologies
  • Radiology practices and education
  • Medical and Biological Sciences
  • Head and Neck Surgical Oncology
  • Immune cells in cancer
  • Ion Channels and Receptors

Capital Medical University
2009-2025

Beijing Friendship Hospital
2022-2025

Shanxi Medical University
2024

Second Hospital of Shanxi Medical University
2024

Northwestern University
2024

Neurological Surgery
2024

Beijing Tongren Hospital
2015-2023

Beijing Chao-Yang Hospital
2017-2023

Peking University People's Hospital
2022

Peking University
2022

Background: Although patients with an anterior cruciate ligament (ACL) injury have a high risk of developing posttraumatic osteoarthritis (PTOA), the role meniscus hypertrophy and mineralization in PTOA after ACL remains unknown. Purpose/Hypothesis: The purpose this study was to determine if menisci respond abnormal loading results calcification. hypotheses were that (1) mechanical induces mineralization, which correlates articular cartilage damage vivo, (2) on bovine explants overexpression...

10.1177/0363546515621285 article EN The American Journal of Sports Medicine 2016-01-20

Binding of the chemokine stromal cell-derived factor-1 (SDF-1) to its receptor C-X-C type 4 (CXCR4) results in activation and subsequent release matrix metalloproteinases (MMPs) that contribute osteoarthritis (OA) cartilage degradation. As hypoxia is a defining feature chondrocyte microenvironment, present study investigated possible mechanism through which SDF‑1 induces degradation under hypoxic conditions. To do this, OA cultures patient tissue explants pretreated with CXCR4 inhibitor,...

10.3892/mmr.2016.5419 article EN cc-by-nc-nd Molecular Medicine Reports 2016-06-21

Objective To evaluate the feasibility and safety of an individualized reassemblable three‐dimensional (3D) printing navigation template for making accurate punctures during sacral neuromodulation (SNM). Methods From July 2016 to 2017, 24 patients undergoing SNM were enrolled. Conventional X‐ray guidance was used in control group, which included 14 patients, while 3D experimental 10 patients. The number punctures, average puncture time, exposure X‐ray, adjustment time operation testing...

10.1002/nau.23769 article EN Neurourology and Urodynamics 2018-07-27

Preoperative anatomical scoring system is conducive to comparison between treatment options and evaluation of postoperative outcomes in patients with small renal tumors. This study aimed evaluate the clinical application efficacy R.E.N.A.L. nephrometry score (RNS) predicting perioperative tumor who underwent laparoscopic partial nephrectomy (LPN).The data 139 tumors LPN 2009 2015 were collected analyzed. Patients divided into three groups according their RNS (low, moderate, high). Clinical...

10.4103/0366-6999.213973 article EN cc-by-nc-nd Chinese Medical Journal 2017-09-04

Background: Conventional magnetic resonance imaging (MRI) has been demonstrated to be a valuable tool in diagnosing osteochondral lesions of the talus. No previous study, our knowledge, evaluated diagnostic ability fat-suppressed fast spoiled gradient-echo (FSPGR) MRI We sought compare three-dimensional FSPGR with conventional Methods: Thirty-two consecutive patients clinically suspected cartilage undergoing and were assessed. Sensitivity, specificity, accuracy diagnosis determined using...

10.7547/1000189 article EN Journal of the American Podiatric Medical Association 2010-05-01

Western blot of synovial fluid has been widely used for osteoarthritis (OA) research and diagnosis, but there is no ideal loading control this purpose. Although β-actin extensively as in western blot, it not suitable because required a cytoskeletal protein. A good OA studies should have unchanged content fluids from normal groups, protein can vary with changes vascular permeability onset. In study, we explore the potential using α1-antitripsin (A1AT) blot. A1AT level elevated inflammatory...

10.4172/2161-1149.s6-006 article EN Rheumatology Current Research 2015-01-01

To investigate the cosmetic outcomes of secondary intention healing small (<1.5cm) nasal ala and tip defects.From August 2017 to October 2020, 42 patients with reconstructions using were included. Defects after excision ranged from 0.5cm×0.7cm 1.2cm×1.5cm in size. Foam dressing covering wounds was changed every 3 5 days. Wound esthetic graded as excellent, good, acceptable, poor based on definitions described literature.All healed 4 weeks, uniform color, no obvious adverse reactions high...

10.2147/ccid.s361662 article EN cc-by-nc Clinical Cosmetic and Investigational Dermatology 2022-10-01

To evaluate the effectiveness of pedicle subtraction osteotomy (PSO) assisted with anterior column reconstruction in treatment chronic osteoporotic vertebral compression fracture (OVCF).Between January 2008 and October 2014, 11 cases OVCF were treated. There 2 males 9 females, aged 65-76 years (mean, 72.3 years). The segment involved T11 cases, T12 L1 4 L2 L3 1 case. At preoperation, Oswestry disability index (ODI) score was 31.1±10.2; kyphosis Cobb angle fractured vertebrae (36.5±10.2)° on...

10.7507/1002-1892.20160116 article EN PubMed 2016-05-08

Objective: To compare the clinical efficacy and safety of single incision mini slings (contasure needless, C-NDL) tension-free vaginal tape obturator (TVT-O) in treatment pure female stress urinary incontinence(SUI). Methods: Clinical data 107 SUI patients who underwent C-NDL (n=51) or TVT-O (n=56) procedure during October 2013 2017 Department Urology, Beijing Chaoyang Hosptial, Capital Medical University were enrolled.The age group was (58.8±9.3) years (range: 43 to 81 years) vs.(56.9±11.4)...

10.3760/cma.j.cn112139-20191210-00603 article EN PubMed 2020-05-01

Abstract Background Endovascular treatment has been recognized as the first line therapy for renal artery aneurysm (RAA). However, RAA related with malignancies had sporadically reported in literature. Stent insertion should be contraindicated RAAs malignant etiology, whereas surgery optimal. Case presentation A 40-year-old female underwent covered stent to exclude left suspected Takayasu arteritis a reginal hospital. Three months later recurred sign of threatened rupture, and patient was...

10.1186/s12893-019-0622-5 article EN cc-by BMC Surgery 2019-10-26

The concept and methods of evidence-based medicine(EBM)has been evolved to impact almost all fields health care policy since it first appeared in 1992.but the field dentistry or stomatology,many problems remain be solved carrying out EBM.The necessity feasibility implementing education China were discussed this paper for chnical decision making clinical research.The contenk teaching approach accreditation tools EBM dental also proposed. Key words: Stomatology; Evidence-based...

10.3760/cma.j.issn.2095-1485.2011.01.016 article EN Zhonghua yixue jiaoyu tansuo zazhi 2011-01-20

Abstract Background Implant-related infections (IRIs) after sacral neuromodulation (SNM) carry a high morbidity. Meanwhile, studies on care bundles report lower infection rate. Herein, we investigate the effectiveness of prevention bundle (IPB) in minimizing IRIs SNM. Methods An IPB focused pre-operative checklists, weight-based antibiotic prophylaxis, strict draping and surgical techniques, wound education; was implemented our center February 2018. performed retrospective review patients...

10.21203/rs.3.rs-3352619/v1 preprint EN cc-by Research Square (Research Square) 2023-09-19

:Objective To discuss therole of assistance intraoperative uitrasonography in ret-roperitoneal laparoscopicnephron-sparing surgery for renal tumors. Methods The laparoscopicultrasonography was applied retroperitoneal nephron-sparing 20 patients, ofwhom 11 were men and 9 women. average age 53(range 33 to 73) years. Therewere 12 patients with cell carcinoma the mean tumor size 2.9(range 1.4 to4.6)cm diame-ter. All them staged as T1 N0 M0. Seven hadangiomyolipoma 4.5(range 1.8 8.0)cm diameter...

10.3760/cma.j.issn.1000-6702.2009.04.006 article EN 2009-04-15

应用标准大骨瓣减压术治疗急性颅内血肿或弥漫性脑舯胀,可有效地清除血肿,解除脑疝、颅高压,降低病死牢和伤残率,但常常并发骨窗下积液.其中包括硬膜下积液及头皮下积液.解放军第九十八医院神经外科白1995年1月至2006年12月共为193例患者行双侧标准大骨瓣减压术,术后并发双侧骨窗下积液27例,现将情况分析报告如下。

10.3760/cma.j.issn.1671-8925.2008.08.030 article ZH-CN Chinese Journal of Neuromedicine 2008-08-15

Background: The aim of this study was to investigate the application value laparoscopic ultrasound (LU) in retroperitoneal radical nephrectomy for renal cell carcinoma with Type II inferior vena cava tumor thrombectomy (RRN-RCC-TII-IVCTT). Methods: clinical data (operative time, length thrombus, length, intraoperative bleeding, stage, histological type, residual tissue, and postoperative follow-up) 6 patients who underwent LU-guided RRN-RCC-TII-IVCTT were retrospectively analyzed, experience...

10.4103/ijc.ijc_153_18 article EN cc-by-nc-sa Indian Journal of Cancer 2022-06-29
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