A5090298308- Hematopoietic Stem Cell Transplantation
- Respiratory Support and Mechanisms
- Acute Myeloid Leukemia Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Polyomavirus and related diseases
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Neuroscience of respiration and sleep
- Cancer survivorship and care
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Cardiac Imaging and Diagnostics
- Neutropenia and Cancer Infections
- Obstructive Sleep Apnea Research
- Intensive Care Unit Cognitive Disorders
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Multiple Myeloma Research and Treatments
- Pain Management and Opioid Use
- Antiplatelet Therapy and Cardiovascular Diseases
- Craniofacial Disorders and Treatments
- Opioid Use Disorder Treatment
- Reconstructive Facial Surgery Techniques
- Cutaneous lymphoproliferative disorders research
Medtronic (Italy)
2017-2023
Medtronic (United States)
2021
University of Rome Tor Vergata
2012-2018
Ospedale SS. Annunziata
2017-2018
Policlinico Tor Vergata
2017
Azienda Ospedaliera Carlo Poma
2017
Azienda Ospedaliero Universitaria San Giovanni Battista
2016
John Wiley & Sons (United States)
2016
Novem (Netherlands)
2012
University of Naples Federico II
2012
Abstract Aims Treatment guidelines for patients with atrial fibrillation (AF) suggest that should be managed an antiarrhythmic drug (AAD) before undergoing catheter ablation (CA). This study evaluated whether pulmonary vein isolation employing cryoballoon CA is superior to AAD therapy the prevention of arrhythmia (AA) recurrence in rhythm control naive paroxysmal AF (PAF). Methods and results A total 218 treatment symptomatic PAF were randomized (1 : 1) (Arctic Front Advance, Medtronic) or...
Aims:The safety and efficacy of rotational atherectomy (RA) in patients presenting with non-ST-elevation myocardial infarction (NSTE-ACS) remain to be defined.The aim our study was assess the RA NSTE-ACS reference both short-and long-term follow-up. Methods results:This an observational retrospective registry which enrolled all consecutive undergoing RA, comparing stable angina (SA) NSTE-ACS.In addition, ACS were matched those not RA.The primary endpoint angiographic success.Procedural...
BACKGROUND: The frequency and temporal distribution of postoperative respiratory depression (RD) events are not completely understood. This study determined the RD episodes in postsurgical patients continuously monitored by bedside capnography pulse oximetry. METHODS: was a post hoc subset enrolled PRediction Opioid-induced Depression In capnoGraphY (PRODIGY) trial from 2 sites United States. These had undergone continuous monitoring on general care wards. data were adjudicated for potential...
Hemorrhagic cystitis (HC) occurring after allogeneic transplantation significantly affects quality of life and, in some cases, becomes intractable, increasing the risk death. To date, its therapy is not established. We used hemostatic agent fibrin glue (FG) to treat 35 patients with refractory post-transplantation HC. Of 322 adult undergoing an for hematological malignancy, developed grade ≥ 2 HC conventional and were treated FG, diffusely sprayed on bleeding mucosa by endoscopic applicator....
Despite the high incidence of respiratory depression on general care floor and evidence that continuous monitoring improves patient outcomes, cost–benefit pulse oximetry capnography patients remains unknown. This study modeled cost length stay savings, investment break-even point, likelihood savings for at risk depression. A decision tree model was created to compare intermittent versus monitoring. The utilized costs outcomes from PRediction Opioid-induced Depression In monitored by...
Cryoballoon ablation (CBA) as a first-line rhythm control strategy is superior to antiarrhythmic drugs (AADs) for preventing atrial fibrillation (AF) recurrence; the impact of CBA on quality life (QoL) and symptoms has not been well characterized.Patients aged 18 75 with symptomatic paroxysmal AF naïve therapy were randomized (1:1) (Arctic Front Advance, Medtronic) or AAD (Class I III). Symptoms QoL assessed at baseline, 1, 3, 6, 9, 12 months using EHRA classification Atrial Fibrillation...
<h2>Abstract</h2> The use of granulocyte colony-stimulating factor (G-CSF) primed bone marrow (G-BM) has been recently considered as an alternative to mobilized hematopoietic stem cells from peripheral blood (G-PB), especially in the haploidentical transplant setting. purpose this study was compare effect vivo G-CSF priming on BM and PB hematopoietic, mesenchymal (MSC), immune cells. Forty healthy donors undergoing harvest for were given subcutaneous recombinant human 7 days. samples...
BACKGROUND From 2011 to 2014, a total of 71% the 3834 patients with hematologic malignancies successfully identified matched unrelated donor (MUD) through Italian Bone Marrow Donor Registry (IBMDR), corresponding transplant efficiency 62%. STUDY DESIGN AND METHODS 2006, Rome Transplant Network (RTN) followed hierarchical selection strategy for alternative search: first MUD, second cord blood, and third haploidentical donor. Using low‐resolution HLA, preliminary query (PQ) was performed in...
A 15-year-old boy showed progressive aortic valve regurgitation during follow-up of supracristal ventricular septal defect. This anatomic arrangement is consistent with the Laubry-Pezzi syndrome in which prolapse a non-coronary cusp due to Venturi's effect results insufficiency.
Postoperative monitoring of respiratory status on general care wards typically consists intermittent checks oxyhemoglobin saturation and rate, allowing substantial unmonitored time for severe opioid induced depression (RD) to develop unnoticed. Oxygen desaturation index (ODI) can be computed solely by continuous pulse oximetry monitoring. In this post-hoc analysis, we evaluate whether nocturnal ODI correlates with RD.The PRODIGY trial (NCT02811302) was a multinational study conducted where...
Abstract Objectives Evaluate safety and efficacy of polymer‐free biolimus‐eluting stents (PF‐BESs) versus ultrathin in unprotected left main (ULM) or bifurcation. Background PF‐BESs due to reduced length dual antiplatelet therapy (DAPT) are increasingly used. However, there limited data about for ULM Methods We selected all‐patients treated bifurcation from two multicenter real life registries (RAIN [NCT03544294] evaluating stents, CHANCE [NCT03622203] appraising PF‐BES). After propensity...
Supplemental oxygen (SO) potentiates opioid-induced respiratory depression (OIRD) in experiments on healthy volunteers. Our objective was to examine the relationship between SO and OIRD patients surgical units.This post-hoc analysis utilized a portion of observational PRediction Opioid-induced Depression In monitored by capnoGraphY (PRODIGY) trial dataset (202 patients, two sites), which involved blinded continuous pulse oximetry capnography monitoring postsurgical units. incidence...
BACKGROUND: Opioid-induced respiratory depression (OIRD) is common on the medical and surgical wards associated with increased morbidity health care costs. While previous studies have investigated risk factors for OIRD, role of race remains unclear. We aim to investigate association between OIRD occurrence medical/surgical ward. METHODS: This a post hoc analysis PRediction Depression In patients monitored by capnoGraphY (PRODIGY) trial; prospective multinational observational blinded study...