A5046272448- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Esophageal Cancer Research and Treatment
- COVID-19 Clinical Research Studies
- Liver Diseases and Immunity
- Physical Activity and Health
- Cardiac Health and Mental Health
- COVID-19 diagnosis using AI
- Gastric Cancer Management and Outcomes
- Catalytic Cross-Coupling Reactions
- Colorectal Cancer Screening and Detection
- COVID-19 and Mental Health
- Lung Cancer Treatments and Mutations
- COVID-19 epidemiological studies
- Global Cancer Incidence and Screening
- Food Security and Health in Diverse Populations
- Sulfur-Based Synthesis Techniques
- Metabolism, Diabetes, and Cancer
- HIV/AIDS drug development and treatment
- RNA modifications and cancer
- Diet, Metabolism, and Disease
- Esophageal and GI Pathology
- Machine Learning in Healthcare
University of Hong Kong
2022-2025
Chinese University of Hong Kong
2023-2025
University of Hong Kong - Shenzhen Hospital
2025
Chinese People's Liberation Army
2024
Fudan University
2019-2020
Taizhou University
2019-2020
State Key Laboratory of Genetic Engineering
2019-2020
Henan University of Science and Technology
2018
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 infection, has been spreading globally. We aimed to develop a clinical model predict the outcome of patients with COVID-19 infection early.Demographic, and first laboratory findings after admission 183 (115 survivors 68 non-survivors from Sino-French New City Branch Tongji Hospital, Wuhan) were used predictive models. Machine learning approaches select features patients' outcomes. The area under...
The incidence of primary liver cancer (PLC) continues to increase worldwide. trends and patterns PLC associated with different age at diagnosis remain unknown.We collected detailed information on between 1990 2017 from Global Burden Disease Study 2017. Estimated annual percentage changes in the age-standardized rate (ASR) diagnosed by age, sex, region, etiology were calculated quantify temporal ASR.Globally, number cases for which was <30 years decreased 17,381 14,661 2017, whereas 30 59 ≥60...
The incidence and mortality of esophageal cancer are high, with 5.90 new cases 5.48 deaths per 100 000 people worldwide in 2017. prognosis is poor, an overall 5-year survival rate less than 20%. Esophageal different geographical locations has etiologies, the continue to rise some regions.We collected data by age gender for 195 countries territories from 1990 2017 Global Burden Disease (GBD) database. And we used these calculate estimated annual percentage change (EAPC) quantify trends...
Abstract Background Predictions of primary liver cancer (PLC) incidence rates and case numbers are critical to understand plan for PLC disease burden. Methods Data on from 1990 2017 were retrieved the Global Burden Disease database. The estimated average percentage change (EAPC) was calculated quantify trends age-standardized (ASRs). Bayesian age-period-cohort models constructed project through 2030. Results Globally, number doubled 472 300 in 953 100 2017. will further increase 1 571 200...
Abstract Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been spreading globally. The number of deaths increased with the increase in infected patients. We aimed to develop a clinical model predict outcome COVID-19 patients early. Methods Epidemiological, clinical, and first laboratory findings after admission 183 (115 survivors 68 nonsurvivors) from Sino-French New City Branch Tongji Hospital were used...
Liver cancer is a commonly diagnosed malignancy in China. The etiologies of liver are widely known, although studies on temporal trends caused by specific rare.Data the incidence and mortality were retrieved from Global Burden Diseases Study 2017. estimated annual percentage change (EAPC) was used to quantify age-standardized rate (ASIR) (ASMR) 1990 2017.Nationwide, number incident cases increased 258 000 515 900 ASIR decreased 27.16 per 100 26.04 during this period, with an EAPC -0.64 (95%...
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic diseases worldwide. We provided a comprehensive description regarding burden NAFLD in 204 countries and territories.We reported deaths disability-adjusted life years (DALYs) related to Global Burden Disease database by sex, age, specific causes, regions. Estimated annual percentage change was applied describe changing trends.Globally, NAFLD-related DALYs 2019 were 0.17 million [95% uncertainty interval (UI): 0.13 0.21]...
Poor survival and restricted function of transplanted stem cells are regarded as limiting their efficacy in wound recovery greatly. Consequently, it is necessary to identify innovative therapeutic strategies solve these issues. Firstly, the biological effect PF-127 hydrogel alone combination with SAP on survival, migration cultured HUCMSCs was assessed by cell viability, apoptosis, scratch assays. S. aureus E. coli were used evaluate antibacterial activity plus combination. Further, ability...
Aim We assessed the correlations between non‐invasive fibrosis scores and mortality in both general population non‐alcoholic fatty liver disease (NAFLD) patients. Methods used data from US National Health Nutrition Examination Survey 1988–2014. The NAFLD score (NFS), Fibrosis‐4 index (FIB‐4) score, aspartate aminotransferase to platelet ratio (APRI) Forns were calculated at baseline. associations of these with risk determined using additive Cox proportional hazard models. area under receiver...
To investigate the epidemiological characteristics and mutation spectrum of monogenic diseases in Chinese population through a large-scale, multicenter carrier screening.
Objective To analyze the trend of reported incidence hepatitis B (HB) in China from 2004 to 2017 provide evidences for developing strategies on HB prevention and control. Methods From National Public Health Science Data Center, we extracted data 31 provincial-level administrative divisions (not including Chinese Taiwan, Hong Kong Special Administrative Region Macao Region) March through 2017. The average annual percentage change (AAPC) region-, gender- age group-specific were calculated...
Background: Temporal trends of primary liver cancer (PLC) vary worldwide. Predictions PLC incidence and case numbers are critical for the understanding planning disease burden.Methods: Data on number from 1990 to 2017 were retrieved Global Burden Disease database. The estimated average percentage change (EAPC) was calculated quantify age standardized rates (ASRs). Bayesian age-period-cohort models constructed project through 2030.Findings: Globally, doubled 472,300 in 953,100 2017. will...
Sallis et al's social support scale for physical activity (SSSPH) is one of the most widely used scales to measure exercise-related yet has never been translated and validated in Chinese. The current study aims simplify, translate, validate a short form SSSPH Chinese population.A simplified version (SSSPH-SC) retaining 6 items was achieved after translation back-translation process, which showed good content validity. then assessed among convenience sample 266 adults from various...
Background: The incidence of liver cancer continues to increase worldwide. trends and onset patterns associated with different ages remain unknown. Methods: We collected detailed information on between 1990 2017 from the Global Burden Disease Study (GBD) study 2017. Estimated annual percentage changes (EAPCs) in age-standardized rate (ASR) by age, sex, region, aetiology were calculated quantify temporal ASR. Findings: ASR very-early-onset (onset at < 30 years) earlyonset 30-59 decreased both...