Xiaodong Cheng

ORCID: 0000-0003-4054-999X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced Fluorescence Microscopy Techniques
  • Thermal Expansion and Ionic Conductivity
  • Advanced biosensing and bioanalysis techniques
  • Ferroelectric and Piezoelectric Materials
  • Microtubule and mitosis dynamics
  • Biosensors and Analytical Detection
  • Plasmonic and Surface Plasmon Research
  • Lipid Membrane Structure and Behavior
  • DNA and Nucleic Acid Chemistry
  • Advanced Battery Materials and Technologies
  • Microwave Dielectric Ceramics Synthesis
  • Nanoparticle-Based Drug Delivery
  • RNA Interference and Gene Delivery
  • Characterization and Applications of Magnetic Nanoparticles
  • Advanced Electron Microscopy Techniques and Applications
  • Cellular transport and secretion
  • Erythrocyte Function and Pathophysiology
  • Photoacoustic and Ultrasonic Imaging
  • Magnetic Properties of Alloys
  • Thermodynamic and Structural Properties of Metals and Alloys
  • Near-Field Optical Microscopy
  • Microstructure and Mechanical Properties of Steels
  • Protist diversity and phylogeny
  • Nanopore and Nanochannel Transport Studies

Wenzhou Medical University
2024-2025

Institute of Macromolecular Chemistry
2025

Sinopec (China)
2024

Sinopec Research Institute of Petroleum Processing
2024

Xiamen University
2021-2022

Georgia State University
2017-2021

Jiangsu University
2006-2019

Hunan University
2010-2017

State Key Laboratory of Chemobiosensing and Chemometrics
2010-2017

Changsha University
2014

We present a high-throughput strategy for sensitive detection of H2S by using individual spherical Au–Ag core–shell plasmonic nanoparticles (PNPs) as molecular probes. This method is based on quantification color variation the single PNPs resulting from formation Ag2S particle surface. The spectral response range 51 nm PNP was specifically designed to match most region cameras. A high density immobilized and rapid RGB (red/green/blue) analysis allow large number be monitored simultaneously,...

10.1021/ac500376e article EN Analytical Chemistry 2014-05-08

Single-molecule photocatalysis at defects in 2D layered materials display distinct dynamic features.

10.1126/sciadv.abj4452 article EN cc-by-nc Science Advances 2021-10-01

Nanoconfinement imposes physical constraints and chemical effects on reactivity in nanoporous catalyst systems. In the present study, we lay groundwork for quantitative single-molecule measurements of environment heterogeneous catalysis nanoconfinement. Choosing hydrophobicity as an exemplary environmental factor, compared a range essential parameters oxidation reaction platinum nanoparticles (NPs) confined hydrophilic hydrophobic nanopores. Single-molecule experimental at single particle...

10.1021/jacs.0c05905 article EN Journal of the American Chemical Society 2020-07-20

Real time observation of chemical reactions individual noble metal nanoparticles (MNPs) is fundamentally important to their controlled synthesis, sensing and catalysis applications. Here, with a simple high-throughput single-molecule darkfield spectral imaging technique, we demonstrate that the reaction-induced plasmonic resonance variations multiple MNPs could be monitored in parallel. Oxidation kinetics gold nanorods (AuNRs), either immobilized on glass substrate or moving freely...

10.1021/ac101933y article EN Analytical Chemistry 2010-09-17

Herein, we demonstrated a new optical microscopy method to selectively image small-size gold nanoparticles (GNPs) inside noisy living cells through determination of the difference between probe beam (illuminated at resonance wavelength GNPs, 532 nm) and reference 473 nm). From computer simulation single-particle imaging experiments, that GNPs with diameter 45 nm could be imaged in GNPs/cell lysates mixture by dual-wavelength (DWD) imaging. The diffusion dynamics nucleic acids functionalized...

10.1021/ac2012366 article EN Analytical Chemistry 2011-09-09

Spectral chemical sensing with digital color analysis by using consumer imaging devices could potentially revolutionize personalized healthcare. However, samples small spectral variations often cannot be differentiated in due to the nonlinearity of appearance. In this study, we address problem exploiting image formation mechanism photography. A close examination processing pipeline emphasizes that although can represented digitally, it is still a reproducible subjective perception rather...

10.1021/ac501448w article EN Analytical Chemistry 2014-07-22

Intracellular transport is a fundamental process crucial for cellular function, driven by the coordinated action of motor proteins that move cargo along microtubule tracks. Traditional tracking methods primarily focus on trajectories, often overlooking rotational dynamics and their impact interactions with complex network. To address this limitation, we introduced digitally assisted single-particle (dSPT) method significantly advances angular resolution intracellular dynamics. By integrating...

10.1021/acs.analchem.4c07046 article EN Analytical Chemistry 2025-04-17

We developed a novel method for counting single gold nanoparticles in free solution with flash-lamp darkfield microscopy and demonstrated that it could be applied to highly sensitive DNA hybridization detection based on target induced AuNP aggregation counts reduction.

10.1039/c2an16171k article EN The Analyst 2012-01-01

The translational and rotational dynamics of anisotropic optical nanoprobes revealed in single particle tracking (SPT) experiments offer molecular-level information about cellular activities. Here, we report an automated high-speed multidimensional SPT system integrated with a deep learning algorithm for the 3D orientation gold nanoparticle probes living cells high localization precision (<10 nm) temporal resolution (0.9 ms), overcoming limitations under low signal-to-noise ratio (S/N)...

10.1021/acs.nanolett.3c04870 article EN Nano Letters 2024-02-28

We have developed a high-resolution nonfluorescent imaging method based on superlocalization of gold nanorods (AuNRs). By taking advantage their anisotropic optical property the plasmonic scattering AuNRs, selective only fraction AuNRs can be achieved by rotating sample relative to linear polarized illumination under cross-polarization microscopy with high NA objective. The AuNR positions obtained from series images could then used reconstruct overall image. Two center-to-center distances 80...

10.1021/ac403512w article EN Analytical Chemistry 2014-02-18

We present a highly sensitive Pb<sup>2+</sup> detection method by <italic>in situ</italic> real-time imaging of catalyzed etching and size reduction immobilized single gold nanoparticles with darkfield microscopy.

10.1039/c4ay00590b article EN Analytical Methods 2014-01-01

Abstract ZrW 2 O 8 /Cu composites were prepared by the powder metallurgy method. Electroless plating was used to deposit copper on before sintering. The thermal expansion and conductivity of measured in temperature range from 25 o C 200 compared with those predicted various theoretical models. results show that coefficient / Cu a different volume fraction is greater than theoretically calculated value. conductivities increase higher content decrease upon elevated temperature. lower

10.1002/mawe.200800322 article EN Materialwissenschaft und Werkstofftechnik 2008-09-01

We present a 3D darkfield imaging method for tracking AuNPs. With this approach, we recorded the entire transmembrane process of cell-penetrating peptide (CPP) modified AuNPs from plasma membrane surface to deep inside cell.

10.1039/c4ay01813c article EN Analytical Methods 2014-10-06

Donor-acceptor-donor (D-A-D) type polycyclic aromatic hydrocarbon and its derivatives have been widely used in the design of photovoltaic materials made great breakthrough recent years, due to their advantages unique large planar structure, high charge mobility, excellent light absorption performance, thermal stability.The latest research progress small-molecule based on D-A-D hydrocarbons is reviewed.The relationships between properties molecular structures are analyzed systematically.

10.6023/cjoc202005023 article EN Chinese Journal of Organic Chemistry 2020-01-01
Coming Soon ...