- Nasolacrimal Duct Obstruction Treatments
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Facial Rejuvenation and Surgery Techniques
- Retinal Imaging and Analysis
- Sinusitis and nasal conditions
- Ophthalmology and Visual Impairment Studies
- Reconstructive Facial Surgery Techniques
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Marine Ecology and Invasive Species
- Protein Interaction Studies and Fluorescence Analysis
- Metal complexes synthesis and properties
- RNA modifications and cancer
- Ocular Oncology and Treatments
- Nonmelanoma Skin Cancer Studies
- Nuclear Structure and Function
- Pancreatic and Hepatic Oncology Research
- Autophagy in Disease and Therapy
- Dermatologic Treatments and Research
- Retinal Diseases and Treatments
- Vascular Malformations Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Nasal Surgery and Airway Studies
- Sympathectomy and Hyperhidrosis Treatments
Hainan Medical University
2025
Shanxi Medical University
2023-2025
Hangzhou Medical College
2017-2024
Zhejiang Provincial People's Hospital
2012-2024
Second Affiliated Hospital of Zhejiang University
2013-2024
Zhejiang University
2022-2024
Alibaba Group (China)
2024
Affiliated Hospital of Guizhou Medical University
2021
Guiyang Medical University
2021
Shanghai Medical College of Fudan University
2016
Purpose. To describe the morphological characteristics and efficacy of OCTA in detecting CNV nAMD. We retrospectively reviewed 53 patients (86 eyes) with suspected secondary to wet AMD. All underwent a multimodal assessment for CNV. Two independent readers calculated sensitivity specificity compared FA. A qualitative analysis was also performed appearance Among 86 eyes patients, 52 were diagnosed as having based on FA imaging analysis. According FA, classified classic 28 eyes, predominantly...
Abstract Gastric cancer (GC) stage and tissue differentiation affect treatment efficacy prognosis, highlighting the importance of understanding risk factors that these parameters. Therefore, this study analyzed affecting GC relationships between site sex age patient. We collected clinical data from 6961 patients with GC, including sex, age, endoscopic lesion location, pathological differentiation. Patients were grouped based on (early or advanced), (well poorly differentiated), (upper...
Bortezomib (BTZ) is the first proteasome inhibitor approved by FDA featuring a hydrophobic boronic acid skeleton, which contributes to its unstability, poor solubility, and unfavorable pharmacokinetic properties. Hence, effective methodologies address these issues are required. According recent clinical findings, combination chemotherapy involving two or more agents essential for most patients mitigate drug resistance. The 11B NMR spectra indicated generation of tetra-coordinated boron...
The operation sequence of bidirectional endoscopy with topical anesthesia varies among endoscopists, which interferes clinical procedure. study aimed to investigate the influence different sequences on outcomes quality indicators and improve performance. A randomized trial was conducted at affiliated hospital a medical university in China. Outpatients who initially underwent were enrolled. Eligible patients either colonoscopy-first group or esophagogastroduodenoscopy-first group. Dyclonine...
The risk of diabetic cardiovascular complications is closely linked to the length hyperglycemia exposure. Mitophagy plays a significant role in vascular endothelial injury. However, specific mechanisms by which mitophagy contributes injury during sustained remain unclear. In ApoE-/- mice and human umbilical vein cell (HUVEC) models, enhanced following short-term long-term high-glucose Short-term exposure promotes Parkin-mediated upregulates mitochondrial fission protein 1 (Fis1) expression,...
The plasmacytoma variant translocation 1 gene (PVT1) plays an oncogenic role in the initiation and progression of multiple cancers. In this study, by using deep-sequencing data follow-up Cancer Genome Atlas-Uveal melanomas (TCGA-UVM), we assessed association between expression PVT1 clinicopathological characteristics patients with uveal melanoma, mechanism its dysregulation prognostic value. Results showed that high group had a higher proportion epithelioid cell dominant disease (a more...
Gastric cancer is one of the most common malignancies worldwide, and third leading cause cancer-related death. The identification novel biomarkers therapeutic targets critical to improve prognosis. A total 380 patients with primary gastric from TCGA database were analyzed. receiver operating characteristic curves plotted. We further evaluated independent prognostic ability NPC2 expression for overall survival (OS) relapse-free (RFS) through Kaplan-Meier curve Cox analysis. was significantly...
Abstract Purpose To compare efficacy and safety between fibrin sealant assisted limbal conjunctival autograft fixation intra‐operative MMC in pterygium surgery. Methods Prospective, comparative, interventional case series. Forty eyes of 40 patients with nasal primary pterygium, 18 male 22 female, were enrolled. The assigned to two groups, each contained nine 11 female based on the area encroaching onto cornea. In one group, was attached sclera sealant, other 0.02% applied after removed. All...
Abstract To investigate the efficacy of lacrimal endoscopy in diagnosis and treatment primary canaliculitis. This is a retrospective, interventional study. Fifteen patients diagnosed as canaliculitis were investigated, who underwent surgery with from January 2015 to December 2017 at Zhejiang Provincial People's Hospital. Patients subsequently followed post-operatively for least 6 months. Pre- post-operative main measurement included ocular surface symptoms, signs canaliculitis,...
Abstract Purpose To assess long‐term efficacy and safety of self‐made cryopreservative fibrin glue ( SMC ) applied in pterygium surgery. Methods Prospective, comparative, interventional case series. Forty eyes 40 patients with nasal primary pterygium, 24 male 16 female, were enrolled. The assigned to two groups each contained 12 eight female based on the area encroaching onto cornea. In one group, conjunctival autograft was attached sclera stored for 2 months, other commercial kit CK after...
Bicanalicular nasal intubation is widely used in lacrimal drainage system surgery. Its common complication lateral displacement or spontaneous prolapse. When the distal part of silicone tubes cannot be seen nose endoscopically, either repositioning removal could a challenge. We developed simple technique to reposition severe prolapsed tubes. This retrospective study included 6 patients with who had undergone bicanalicular between January 2017 and December 2019. memory wire probe pull nylon...
Genome-wide association studies (GWAS) have identified more than 160 susceptibility loci for colorectal cancer (CRC). The effects of these variants, particularly their mechanisms, however, remain unclear. In this study, a comprehensive functional annotation CRC-related GWAS signals was firstly conducted to identify the potential causal variants. We found that SNP rs7229639 in intron 3 SMAD7 at 18q21.1 might serve as putative variant CRC. is located region with evidence regulatory potential....
Purpose Reconstruction after eyelid lesion excision is very important. It calls for preserving normal function the protection of eye and restoring good cosmesis. important to precisely align tarsal plate. However, unique anatomy eyelids often makes haemostasis difficult surgical field obscured. We report an effective method solve this problem. Method This retrospective study included 25 patients who underwent margin using chalazion clamp between March 2020 October 2021. The placed on desired...
To demonstrate the outcomes of translacrimal canalicular drainage using a lacrimal probe and intranasal by D-silicone intubation for acute dacryocystitis (AD).
To investigate the clinical efficacy of wound exclusion combined with silicone tube bicanalicular intubation for treatment pigmented nevi lacrimal punctum.
Objective: To investigate the distribution characteristics of eye diseases and prevalence causes blindness low vision among adults aged ≥50 years in communities Hangzhou China. Methods: This was a cross sectional investigation, clusters randomly selected individuals at least 50 old from some larger China were sampled, 2 953 enrolled. The participants underwent detailed ophthalmic examinations that included visual acuity, autorefraction, intraocular pressure, slit-lamp assessment...