A5065562995- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Systemic Lupus Erythematosus Research
- Esophageal and GI Pathology
- Alcohol Consumption and Health Effects
- Diet, Metabolism, and Disease
- Gastrointestinal disorders and treatments
- Pharmacological Effects of Natural Compounds
- Abdominal vascular conditions and treatments
- Biliary and Gastrointestinal Fistulas
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Genetic and Kidney Cyst Diseases
- Metastasis and carcinoma case studies
- Parasites and Host Interactions
- Multiple and Secondary Primary Cancers
- Polyomavirus and related diseases
- Full-Duplex Wireless Communications
AZ Sint-Jan
2012-2025
Service Public Fédéral Technologie de l'Information et de la Communication
2021
Erasmus MC
2003-2014
AZ Groeninge
2008
Erasmus University Rotterdam
2003-2006
Ikazia Ziekenhuis
2003
Universitair Ziekenhuis Leuven
2003
Keratin 7 positive (K7+) cells are considered to be activated in case of impaired hepatocyte replication. Their exact role and their interaction with hepatocytes macrophages also implicated liver regeneration remain poorly characterized humans. The aim this study is evaluate hepatocyte, K7+ macrophage populations severe alcohol-related steatohepatitis (sASH) link them injury patients' outcomes. Immunohistochemical morphometric studies for total cells, (CD68+ cells), proliferative (Ki67+...
Double-balloon enteroscopy is a novel technique for visualizing the entire small bowel. Complications have been reported relatively rarely in series published up until now. In this report we describe two patients who developed acute pancreatitis immediately after double-balloon enteroscopy, diagnosed on clinical, biochemical, and radiological grounds. both resolved with supportive care. Based early studies pathogenesis of pancreatitis, discuss possible pathogenetic mechanism arising as...
Summary Background Stopping nucleos(t)ide analogues (NA) after hepatitis B e antigen ( HB eAg) seroconversion is associated with high relapse rates in Asian patients, but data Caucasian cohorts are scarce. Clinical course, outcomes and immunological aspects of chronic infections differ substantially between distinct ethnicities. Aim The aim this study was to determine rates, factors predicting clinical analogue cessation a large, predominantly cohort patients analogue‐induced eAg...
We report the Belgian Registry of 30 patients (19 women and 11 men) with hereditary haemorrhagic telangiectasia (HHT) liver involvement.Twenty-three (77%) were asymptomatic. Within seven symptomatic (23%), four suffered from high output cardiac failure, two died before transplantation one was transplanted. Three developed biliary disease, transplanted listed. Intrahepatic shunts a large hepatic artery (6-14 mm, mean: 9.3 mm) found in all are characteristic involvement. observed prevalence...
Hepatitis B virus (HBV)-hepatitis delta (HDV) coinfection is the most severe form of chronic viral hepatitis, but factors that determine disease progression and severity are incompletely characterised. This long-term follow-up study aims to identify risk for liver-related outcomes. In this multicentre national cohort study, data from admission until last visit between 2001 2023 was retrospectively collected 162 HBV-HDV coinfected patients. The inclusion criteria were HBsAg or HBV DNA...
The goal of treatment in autoimmune hepatitis (AIH) is induction remission to prevent the development liver fibrosis, cirrhosis, and its related complications. Various definitions response have been used. International Autoimmune Hepatitis Group (IAIHG) recently defined consensus criteria for response. We aimed validate IAIHG our cohort establish correlations with survival endpoints.
To prospectively compare single-shot spin-echo echo-planar imaging (SSSE-EPI) using b = 0, 10, 150, and 400 seconds/mm(2) with standard MRI techniques after intravenous super paramagnetic iron oxide (SPIO) in the detection characterization of focal liver lesions focus on small (<10 mm) lesions.A total 25 patients suspected for colorectal metastases were included. Number detected was evaluated. Image quality compared between SSSE-EPI sequence post-SPIO (fat-suppressed T1-weighted [T1w]...
As different hepatitis C virus (HCV) genotypes respond differently to initiated therapy, correct HCV genotyping is essential. A potential risk for misclassification of the intergenotypic circulating recombinant form (CRF) 2k/1b strains exists, depending on method used. The aim was investigate differences in methods with regard CRF and gain insight prevalence 2k/1b. Genotyping results by Versant Genotype Assay were compared nonstructural protein 5B (NS5B) sequencing. In total, from November...
Abstract Background Prevalence data on viral hepatitis B (HBV), C (HCV), and HIV infection in prison are often scarce or outdated. There is currently no systematic screening for these blood-borne infections (BBV) Belgian prisons. an urgency to assess the prevalence of BBV inform policymakers public healthcare. Methods This was a multicentre, interventional study using opt-in prisons across Belgium, April 2019 – March 2020. Prisoners were tested finger prick risk factors assessed...
Abstract Background Radiofrequency ablation (RFA), combined with endoscopic resection, can be used as a primary treatment for low grade dysplasia, high and early esophageal adenocarcinoma (EAC) in Barrett’s esophagus (BE). The aim of the Belgian RFA registry is to capture real-life outcome therapy BE assess efficacy safety outside study protocols, absence reimbursement. Patients methods Between February 2008 January 2017, data from 7 different expert centers were prospectively collected...
Introduction Nationwide studies comparing patients with hepatitis B and C virus (HBV HCV) infections are mandatory for assessing changes in epidemiology. Aim The aim of this study was to compare epidemiological data initial management newly diagnosed persistent HBV (HBsAg positive) or HCV (detectable RNA) infection Belgium. Patients methods Data were extracted from two Belgian observational databases. Results A total 655 (387 268 included. Compared patients, younger, more frequently men,...
Introduction Hepatitis C virus (HCV) is a major global health issue and successful treatment has been associated with reduction of risk all-cause mortality. Advancements have made in HCV through the use interferon-free regimens. Most trials conducted genotype (GT) 1 data for regimens GT4 patients are limited. The aim this study was to evaluate safety efficacy sofosbuvir plus simeprevir real-world cohort advanced fibrosis. Patients Methods Eighty-seven treatment-naïve or –Interferon (IFN)...
Introduction. Pancreatic actinomycosis is a chronic infection of the pancreas caused by suppurative Gram-positive bacterium Actinomyces. It has mostly been described in patients following repeated main pancreatic duct stenting context pancreatitis or surgery. This type often erroneously interpreted as malignancy due to specific invasive characteristics Case. A 64-year-old male with history and presented weight loss, fever, night sweats, abdominal pain. CT imaging revealed mass tail, invading...