A5081530327- Cardiovascular Conditions and Treatments
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Veterinary Medicine and Surgery
- Sports injuries and prevention
- Congenital heart defects research
- Cardiac electrophysiology and arrhythmias
- Coronary Artery Anomalies
- Aldose Reductase and Taurine
- Mechanical Circulatory Support Devices
- Cardiovascular Disease and Adiposity
- Hemodynamic Monitoring and Therapy
- Vascular anomalies and interventions
- Cardiac Imaging and Diagnostics
- Streptococcal Infections and Treatments
- Human-Animal Interaction Studies
- Veterinary Orthopedics and Neurology
- Venous Thromboembolism Diagnosis and Management
- Veterinary Pharmacology and Anesthesia
- History and Developments in Astronomy
- Cardiac pacing and defibrillation studies
The Schwarzman Animal Medical Center
2015-2025
Cornell University
1983-2019
Hawaii Agriculture Research Center
2019
Louisiana State University
2013
Tufts University
1987-2008
New York State College of Veterinary Medicine
1991-2008
Bayer (Germany)
2008
North Carolina State University
2008
Bayer (United States)
2008
Philadelphia University
2008
This report, issued by the ACVIM Specialty of Cardiology consensus panel, revises guidelines for diagnosis and treatment myxomatous mitral valve disease (MMVD, also known as endocardiosis degenerative or chronic valvular heart disease) in dogs, originally published 2009. Updates were made to diagnostic, well medical, surgical, dietary recommendations. The strength these recommendations was based on both quantity quality available evidence supporting diagnostic therapeutic decisions....
This is the report of American College Veterinary Internal Medicine (ACVIM) Specialty Cardiology consensus panel convened to formulate guidelines for diagnosis and treatment chronic valvular heart disease (CVHD, also known as endocardiosis myxomatous valve degeneration) in dogs. It estimated that approximately 10% dogs presented primary care veterinary practices have disease, CVHD most common many parts world, accounting 75% canine cases seen by North America. commonly affects left...
Abstract Cardiomyopathies are a heterogeneous group of myocardial disorders mostly unknown etiology, and they occur commonly in cats. In some cats, well‐tolerated associated with normal life expectancy, but other cats can result congestive heart failure, arterial thromboembolism or sudden death. Cardiomyopathy classification be challenging, this consensus statement we outline system based on cardiac structure function (phenotype). We also introduce staging for cardiomyopathy that includes...
Background Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on before the onset CHF unknown. Hypothesis/Objectives Administration pimobendan (0.4–0.6 mg/kg/d divided doses) increased size preclinical MMVD, not receiving other cardiovascular medications, will delay signs CHF, cardiac‐related death, or euthanasia. Animals 360 client‐owned MMVD left atrial‐to‐aortic ratio ≥1.6, normalized ventricular...
Necropsy studies in domestic cats have suggested the occurrence of a primary cardiac disease resembling hypertrophic cardiomyopathy (HCM) humans. We used two-dimensional echocardiography to define morphological and functional features HCM during life 46 evaluated subspecialty veterinary clinic. Cats were 8 months 14 years old (mean, 6 years).During follow-up period as long 49 months, 18 died (or euthanatized) due congestive heart failure, peripheral embolization, or both, 3 other experienced...
SUMMARY Hyperthyroidism was diagnosed in 131 cats during a 3½-year period. The ranged age from 6 to 20 years; there no breed or sex predilection. most frequent clinical signs included weight loss, polyphagia, increased activity, polydipsia, polyuria, and vomiting. Common serum biochemical abnormalities high values for alkaline phosphatase activity (75%), lactate dehydrogenase (66%), aspartate transaminase alanine (54%). Electrocardiographic changes tachycardia (≥240 beats/min) R-wave...
Background— Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary familial heart muscle disease associated with substantial cardiovascular morbidity and risk of sudden death. Efforts to discern relevant pathophysiological mechanisms have been impaired by lack suitable animal model. Methods Results— ARVC was diagnosed in 23 boxer dogs (12 male; 9.1±2.3 years old). Clinical events alone or combination included death (n=9; 39%), arrhythmias suspected (RV) origin (n=19; 83%),...
Background Hypertrophic cardiomyopathy is the most prevalent heart disorder in cats and principal cause of cardiovascular morbidity mortality. Yet, impact preclinical disease unresolved. Hypothesis/Objectives Observational study to characterize survival with nonobstructive (HCM) obstructive (HOCM) hypertrophic apparently healthy (AH). Animals One thousand seven hundred thirty client‐owned (430 HCM; 578 HOCM; 722 AH). Methods Retrospective multicenter, longitudinal, cohort study. Cats from 21...
Background —Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary myocardial disease of incompletely resolved pathogenesis and largely unappreciated cause sudden death in the young. Methods Results —Clinical features 12 domestic cats with ARVC (7 male; 1 to 20 years old, mean 7.3±5.2 years) were right-sided congestive heart failure (n=8), supraventricular tachyarrhythmias (n=5), tachycardia (n=3), polymorphic arrhythmias (n=6), bundle-branch block (n=5). was suspected all 8...
Abstract Objective —To determine whether serum N-terminal pro-B-type natriuretic (NT-proBNP) concentration could be used to identify cardiac disease in dogs and assess severity affected dogs. Design —Cross-sectional study. Animals —119 with mitral valve disease, 18 dilated cardiomyopathy, 40 healthy control Procedures —Serum NT-proBNP was measured an ELISA validated for use Results of physical examination, thoracic radiography, echocardiography, biochemical analyses were recorded disease....
Atherosclerosis was diagnosed on necropsy in 21 dogs a 14-year period. Nine died and 12 were euthanatized because of complications associated with the disease. The mean age 8.5 +/- 0.5 years; 18 male. Three breeds (Miniature Schnauzer, Doberman Pinscher, Labrador Retriever) had higher prevalence disease than other canine population Animal Medical Center. Most common clinical signs lethargy, anorexia, weakness, dyspnea, collapse, vomiting. Hypercholesterolemia, lipidemia, hypothyroidism...
B-type natriuretic peptide concentrations reliably distinguish between cardiac and respiratory causes of dyspnea, but its utility to detect asymptomatic cats with occult cardiomyopathy (OCM) is unresolved.Determine whether plasma N terminal probrain (NT-proBNP) concentration can discriminate OCM from normal cats, NT-proBNP correlates clinical, biochemical, echocardiographic parameters.One hundred fourteen normal, healthy cats; 113 cats.Prospective, multicenter, case-controlled study. was...
Changes in clinical variables associated with the administration of pimobendan to dogs preclinical myxomatous mitral valve disease (MMVD) and cardiomegaly have not been described.To investigate effect on relationship between a change heart size time congestive failure (CHF) or cardiac-related death (CRD) MMVD cardiomegaly. To determine whether pimobendan-treated differ from receiving placebo at onset CHF.Three hundred fifty-four cardiomegaly.Prospective, blinded study randomized (ratio 1:1)...
Introduction The correct labeling of a genetic variant as pathogenic is important breeding decisions based on incorrect DNA tests can lead to the unwarranted exclusion animals, potentially compromising long-term health population. In human medicine, American college Medical Genetics (ACMG) guidelines provide framework for classification. This study aims apply these six variants associated with hypertrophic cardiomyopathy (HCM) in certain cat breeds and propose modified criterion Methods...
Clinical cardiac abnormalities developed in 32 of 175 dogs that had various malignancies and were treated with doxorubicin: 31 electrocardiographic including arrhythmias nonspecific alterations the R wave, ST segment, or QRS duration 7 congestive heart failure. All seven failure died within 90 days. At necropsy, 13 affected noninflammatory myocardial degeneration, myocytolysis, vacuolation, and/or fibrosis there was intramural coronary arteriosclerosis all 13. Five lymphosarcoma complete...
M‐mode echocardiography was completed and plasma taurine concentrations were determined in 79 healthy cats 77 with dilated cardiomyopathy (DCM). In cats, a relationship not observed between any echocardiographic measurement. End‐systolic end‐diastolic cardiac chamber dimensions larger; wall thickness measures smaller; calculations of fractional shortening less DCM than cats. Plasma < 30 nmol/mL detected 7/79 52/77 DCM. Of the 52 an initial concentration nmol/mL, 23 died or euthanized...