A5078754655- Autism Spectrum Disorder Research
- Child Nutrition and Feeding Issues
- Family and Disability Support Research
- Child and Adolescent Psychosocial and Emotional Development
- Genetics and Neurodevelopmental Disorders
- Child Development and Digital Technology
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Prenatal Screening and Diagnostics
- Sleep and related disorders
- Genomic variations and chromosomal abnormalities
- Genomics and Rare Diseases
- Attention Deficit Hyperactivity Disorder
- Infant Health and Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Congenital heart defects research
- Sleep and Wakefulness Research
- Virology and Viral Diseases
- Breastfeeding Practices and Influences
- Heart Rate Variability and Autonomic Control
- Congenital Heart Disease Studies
- Fetal and Pediatric Neurological Disorders
- COVID-19 and Mental Health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Eating Disorders and Behaviors
Soroka Medical Center
2013-2025
Ben-Gurion University of the Negev
2015-2025
University Medical Center
2010-2024
Center for Autism and Related Disorders
2022-2024
University Hospital and Clinics
2010-2024
Child Development Center
2022
Trinity College Dublin
2020
Harvard University
2019
Oregon Health & Science University
2008
Barzilai Medical Center
2001
Abstract There has been a dramatic increase in the number of children diagnosed with autism spectrum disorders (ASD) worldwide. Recently anecdotal evidence possible therapeutic effects cannabis products emerged. The aim this study is to characterize epidemiology ASD patients receiving medical treatment and describe its safety efficacy. We analysed data prospectively collected as part program 188 treated between 2015 2017. majority was based on oil containing 30% CBD 1.5% THC. Symptoms...
ABSTRACT The aims of this longitudinal study were to examine (a) development infant sleep and maternal from 3 6 months postpartum; (b) concomitant prospective links between sleep; (c) triadic paternal involvement in caregiving sleep. included 57 families that recruited during pregnancy. Maternal was assessed using actigraphy diaries for 5 nights. Both fathers mothers completed a questionnaire assessing the relative caregiving. results demonstrated moderate improvement percent months. at...
Sensory abnormalities and sleep disturbances are highly prevalent in children with autism, but the potential relationship between these two domains has rarely been explored. Understanding such relationships is important for identifying autism who exhibit more homogeneous symptoms.Here, we examined this using Caregiver Profile Children's Sleep Habits Questionnaire, which were completed by parents of 69 62 age-matched controls.In line previous studies, exhibited severe sensory than controls....
The interactions between premature birth and the caregiving environment on infants' cognitive social functioning were examined. Participants 150 infants (83 preterm, 67 full‐term) their parents. When 6 months old, parents reported levels of emotional distress, triadic family filmed coded. At 12 age, was assessed. Prematurity moderated effects maternal (but not paternal) distress outcomes. Whereas for consistent with a diathesis–stress approach, differential susceptibility approach. groups...
It is widely believed that early diagnosis and treatment of autism spectrum disorder essential for better outcome. This demonstrated by the American Academy Pediatrics recommendation to screen all 1.5–2.5-year-old toddlers disorder. However, multiple longitudinal studies children diagnosed with at 1.5–6 years age treated in community settings have not reported any associations between earlier improved outcome core symptoms. Here, we quantified Longitudinal changes symptoms 131 1.2–5 using...
Abstract Accurate estimation of annual changes in autism spectrum disorders (ASD) prevalence is critical for planning the expansion diagnostic, education, and intervention services at an adequate rate. Previous studies from Israel have reported that ASD among 8‐year‐old children has increased estimates 0.3% 2008 to 0.65% 2015 1.3% 2018. Here, we analyzed data acquired National Insurance Institute Israeli (NII), a governmental organization approves monitors all who receive welfare Israel,...
Several studies have demonstrated that the severity of social communication problems, a core symptom Autism Spectrum Disorder (ASD), is correlated with specific speech characteristics ASD individuals. This suggests it may be possible to develop analysis algorithms can quantify from recordings in direct and objective manner. Here we demonstrate utility new open-source AI algorithm, ASDSpeech, which analyze children reliably their difficulties across multiple developmental timepoints. The...
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that involves difficulties in social communication. Previous research has demonstrated these are apparent the way ASD children speak, indicating it may be possible to estimate severity using quantitative features of speech. Here, we extracted variety prosodic, acoustic, and conversational from speech recordings Hebrew speaking who completed an Diagnostic Observation Schedule (ADOS) assessment. Sixty were 72 21 significantly...
Summary We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n=35,584 total samples, 11,986 with ASD). Using an enhanced Bayesian framework integrate de novo and case-control rare variation, we identify 102 risk genes at a false discovery rate ≤ 0.1. Of these genes, 49 show higher frequencies disruptive variants in individuals ascertained for severe neurodevelopmental delay, while 53 ASD; comparing ASD cases mutations groups reveals phenotypic differences....
The purpose of this study was to determine the efficacy and safety omega-3 fatty acids for children with autistic spectrum disorder (ASD).This an open-label pilot study. Ten aged 4-7 years old ASD according Diagnostic Statistical Manual Mental Disorders, 4(th) edition (DSM-IV), were given 1 gram daily 12 weeks. main outcome measure used Autism Treatment Evaluation Checklist (ATEC). These data collected between July, 2006, June, 2007.Of 9 subjects who completed study, 8 showed improvement...
The majority of studies on child sleep problems focus primarily mothers, neglecting paternal influences. Guided by the transactional framework, we explored how temperament, and maternal stress, parent–child interactions differ between families having children with disturbances a selected comparison group. role involvement in caregiving as moderator these differences was assessed. sample consisted 51 (1–3 years old) their mothers fathers. Data were collected during home visits, when fathers...
To examine longitudinally differences in (1) objective and subjective sleep patterns (2) parenting functioning (i.e. maternal emotional distress, separation anxiety, parental involvement infant care) between room-sharing solitary-sleeping mother–infant dyads. Maternal sleep, sleeping arrangements, were assessed at 3 (N = 146), 6 141), 12 135), 18 130) months postpartum. with actigraphy diaries for five nights. Questionnaires used to assess nighttime breastfeeding, functioning. Persistent...
Abstract A variety of studies have suggested that at least some children with autism spectrum disorder (ASD) view the world differently. Differences in gaze patterns as measured by eye tracking been demonstrated during visual exploration images and natural viewing movies social content. Here we analyzed temporal randomness saccades blinks movies, inspired a recent measure “randomness” applied to micro‐movements hand head ASD (Torres et al., 2013; Torres & Denisova, 2016). We large...
To date, research about feeding disorder (FD) has focused almost exclusively on the mother-child dyad, ignoring fathers' roles. The current study investigated father-child interactions with children having FD. sample consisted of 67 (1-3 years old) and their mothers fathers. Thirty-four children, diagnosed a nonorganic-based FD (FD group) 33 without an (control were matched for age, gender, birth order, maternal education. Data collected during home visits. Mothers interviewed father's...
Attention-deficit hyperactivity disorder (ADHD) is a common childhood-onset psychiatric characterized by inattention, impulsivity and hyperactivity. ADHD exhibits substantial heritability, with rare monogenic variants contributing to its pathogenesis. Here we demonstrate familial caused missense mutation in CDH2, which encodes the adhesion protein N-cadherin, known play significant role synaptogenesis; affects maturation of protein. In line human phenotype, CRISPR/Cas9-mutated knock-in mice...
Parental reflective functioning (PRF) is a core element in the parent–child relationship. This study set out to investigate changes PRF following DUET program, 12-week group intervention program. We proposed that would enhance maternal capacities, resulting better mother-child emotional availability, child self-regulation, and decreased behavioral problems. Seventy mothers completed intervention. Of these mothers, nine were first allocated waiting-list thereafter included an group. was...
Objective We examined how child temperament, parental sense of competence, and paternal involvement predicted observed mealtime dynamics. Method 97 families children with feeding disorder (FD), sleep problems (SP), typically developing (TD) participated in the study. Data were collected during home visits, where mother–child father–child dynamics videotaped parents completed questionnaires. Results More conflict control was mealtimes FD than SP TD groups. Among group, maternal competence...