A5063274163- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Natural product bioactivities and synthesis
- Flavonoids in Medical Research
- Cancer Diagnosis and Treatment
- Traditional Chinese Medicine Analysis
- Hepatitis B Virus Studies
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Treatments and Studies
- Genomics, phytochemicals, and oxidative stress
- COVID-19 and Mental Health
- Polysaccharides Composition and Applications
- Breast Lesions and Carcinomas
- Management of metastatic bone disease
- Neurological Disease Mechanisms and Treatments
- Cancer survivorship and care
- Traditional Chinese Medicine Studies
- Childhood Cancer Survivors' Quality of Life
- Food composition and properties
- COVID-19 and healthcare impacts
- Gene Regulatory Network Analysis
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Breast Cancer Treatment Studies
Harbin Medical University
2020-2024
First Affiliated Hospital of Harbin Medical University
2020-2024
Chongqing Academy of Agricultural Sciences
2024
China National Hybrid Rice R&D Central Hunan Hybrid Rice Reserch Center
2024
Runze (China)
2024
Zigong First People's Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Ningbo No. 2 Hospital
2020
Xian Yang Central Hospital
2020
Tang Hospital
2019
The coronavirus disease 2019 (COVID-19) epidemic has been almost controlled in China under a series of policies, including "early diagnosis and early treatment". This study aimed to explore the association between treatment with Qingfei Paidu decoction (QFPDD) favorable clinical outcomes. In this retrospective multicenter study, we included 782 patients (males, 56 %; median age 46) confirmed COVID-19 from 54 hospitals nine provinces China, who were divided into four groups according...
Background . Although surgery, chemotherapy, radiotherapy, and endocrine therapy are widely used in clinical practice for breast cancer treatment, herbal medicines (HMs) considered as an alternative to palliative treatments because of their coordinated intervention effects relatively low side effects. Astragaloside (AS) chlorogenic acid (CGA) major active ingredients Radix Astragali Lonicera japonica , which have shown antitumorigenic properties certain cancers, but the role HMs containing...
Plant polyphenols, which contain phenolic acids such as chlorogenic acid (CGA), can be used for the treatment of gastrointestinal cancer and have gained increasing attention in recent years. In this study, we explored a novel CGA-containing herbal medicine named LASNB, was extracted from Lonicera japonica Thunb., Agrimonia eupatoria L., Scutellaria barbata D.Don.CGA LASNB analyzed using high-performance liquid chromatography (HPLC). The biological functions molecular mechanisms were...
Pancreatic cancer is one of the most aggressive types malignant tumors and associated with an extremely poor prognosis. Despite numerous research efforts over last few years, little progress has been made in understanding treatment disease. Gemcitabine-based regimens are considered as first-line for pancreatic cancer, but effects chemotherapy on disease limited. Natural products extracted from herbs represent a valuable resource novel bioactive anticancer agents could benefit...
SPC25 is associated with unfavorable outcomes in various cancers, but its role prostate cancer (PRAD) unclear. More research needed on glycolysis and ferroptosis targets PRAD. Bioinformatics tools were used to analyze expression disparities. Gene set enrichment analysis (GSEA) identified pathways enriched by correlation glycolytic proteins. mRNA transcriptional activity was analyzed quantitative polymerase chain reaction (qPCR), while protein levels of SPC25, markers, markers assessed using...
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is an acute, diffuse, inflammatory injury caused by various endogenous or exogenous factors. It currently widely recognized that excessive response resulting from immune imbalance constitutes a crucial pathogenic mechanism in ALI/ARDS. SS31 novel mitochondria-targeted antioxidant peptide. This article validates the role of lipopolysaccharide (LPS)-induced ALI. The study applied transcriptome sequencing, immunofluorescence, PCR,...
The prognosis of lung carcinoma with metastasis to the bone, particularly spine, is poor. Chemotherapy and radiotherapy are established treatments for metastatic bone disease, but their effectiveness unsatisfactory repair following use slow difficult. Medicine prepared from herbal extracts may be an alternative treatment option. present study discusses case a 59-year-old patient diagnosed squamous cell cancer (T2N3M1) in which first-line chemotherapy using docetaxel plus cisplatin failed....
Herbal medicine can present an alternative way of treating liver cancer. Here, we explored a matrine- and sophoridine-containing herbal compound (AH-05) extracted from Adenophora capillaris, Sophora flavescens, Astragalus, other plants. H22 HepG2 cell models, as well xenograft model, were established. Cell proliferation apoptosis measured in vitro, tumor volume weight observed vivo. The activation AKT/mTOR nuclear factor-κB (NF-κB) pathways cells the polarization CD4/CD8 T spleen tested. To...
Abstract Objectives: This study investigates the clinical features and pulmonary functions of COVID-19 pneumonia survivors at 3 or 6 months after diagnosis in Heilongjiang Province, China. Methods: Forty-six patients with diagnosed since February 2020 were enrolled this for follow-up July 2020. These categorized into three groups: Group A (n=24) B (n=11) who moderate severe followed up diagnosis; C six diagnosis. Data on function, arterial blood gas analysis, chest CT, test, antibody...
89 Background: Palliative care is focused and seems as rationally anti-cancer way that have low systemic toxicity acceptable effectiveness for stage IV cancer, especially herbal extracted medicines, which can regulate tumor microenviroment body immune system. Our previous lab studies indicated TGF-beta, EGF, VEGF, IL-10 cytokines expression mico-vessel density be downgraded in by extract preparation from Ginseng, Herba Agrimonia, Hairyvein Arginine etc. Methods: 13 patients with unresectable...
The case of a female who had severe, rare, terminal breast mucinous carcinoma (BMC) and failed to receive surgery chemotherapy was reported. patient diagnosed with pure BMC (ER++, PR++, CerbB-2−, Ki-67 10%) accompanied bilateral lungs, chest walls skin ulcer ( D = 14 cm), lymph nodes armpits, right supraclavicular metastases. ECOG (Eastern Cooperative Oncology Group) NRS (Numeric Rating Scale) pain scores were 4 6, respectively. Because the refused traditional radiotherapy on religious...
The on-going treatments of unresectable pancreatic, hepatocellular and late-stage lung cancer (PC\HCC\LC) are less effectiveness as second-line or later treatment. However, the palliaitve care is alternative option. Here, we reported patients who received palliative by herbal extractive medicines (CHM).
Background: Few studies have examined the association between treatment given time and clinical outcomes, which is indeed of great importance to management coronavirus disease 2019 (COVID-19). We performed this study explore whether early brings favorable outcomes. Methods: In retrospective multicenter study, we included patients aged 18 87 years with confirmed COVID-19 on admission from 54 hospitals in nine provinces China 21 January 10 March, 2020. Final date follow-up was March 17, All...
Background: Since the COVID-19 outbreak, there has been a few articles on pulmonary function studies in patients discharged one month later or three later. However, is no literature mentioned about of hospitalized so far.Methods: In this study, we firstly performed retrospective study to identify changes with 449 inpatients including 141 asymptomatic carriers compared 228 non-COVID-19 outpatients which accepted test health examine center.Results: We found that included had worse even when...