Abstract The global prevalence of prediabetes is on the rise, and it value to manage predisposal diabetes at an early stage. Myricetin a natural polyhydroxyflavonoid, found in planta with several health benefits. This study aimed evaluate effects myricetin prediabetes. In vitro assay indicated that cell viability, endocytosis phagocytosis macrophages were inhibited RAW 264.7 cells under high glucose (HG) levels, concurrent increase reactive oxygen species level. Administration dose 10 μM,...

Abstract Fisetin is one of the most popular flavonoids found in vegetables and fruits with several health benefits such as antidiabetic, anticancer, anti‐inflammatory activities. Biotechnology or chemosynthesis tools were used for synthesis fisetin its analogs to improve their yield efficacy. Structure activity relationships (SARs) revealed that aromatic hydroxyl groups especially 3,4‐dihydroxylation at ring B crucial biological activities, whereas substitution appeared impact original...

Flowering plants from the Syzygium genus have long been used in different ethnomedicinal systems worldwide and under scrutiny for their biological activities. coriaceum , an endemic plant of Mauritius has poorly studied its potential application against cancer. Herein, leaf extract investigated anticancer effect hepatocellular carcinoma (HepG2) cells. The activity was assessed using cell proliferation assays, flow cytometry, JC-1 mitochondrial membrane assay, COMET assay. Un-targeted...

Abstract Apigenin (4′,5,7‐trihydroxyflavone) is a natural flavone reported to present anti‐diabetic and anti‐oxidative bioactivities. The effect of apigenin mitigate endothelial dysfunction in diabetes remains be investigated. In the study, vaso‐protective as well its underlying action mechanisms was investigated using vitro‐ vivo‐based assays. Aortas were detached from C57BL/6J mice for ex vivo treatment, primary rat aortic cells (RAECs) cultured further stimulated high glucose (HG) with or...

Providing postoperative pain management in patients who underwent scrotal surgeries is achieved using several methods, one of which the ultrasound-guided spermatic cord block (US-SCB). To enhance anesthesia quality and extend analgesia postoperatively, agents have been added conjunction with local agents. This study targeted assessing results combining neostigmine levobupivacaine US-SCB for providing perioperative undergoing testicular sperm extraction (TESE) surgery. double-blind,...

Erectile dysfunction is a highly prevalent disorder. It estimated that more than 50% of men who ranged in age from 40 to 70 years old suffer erectile some degree. We aimed this pilot cross-sectional study determine female sexual function and social satisfaction before 6 months after penile prosthesis implant. This was carried on 50 consecutive married women whose husbands underwent malleable implant our department July 2015 2016. Our results showed significant increase desire, lubrication,...

Background: Penile prosthesis (PP), or penile implant, is one of the oldest effective treatments for condition erectile dysfunction and a implant always seen as tool to provide rigidity in penis with no other effects regarding ejaculation. Aim study:To assess any change ejaculatory function after implantation (PPI) Patients Methods: 40 male patients scheduled malleable were included this study.The mean age was (52.5 ± 12) years.Patients married stable relationship.We excluded anejaculation...

Purpose: To evaluate evaluation of the erectile function and mood changes in male patients with Hansen's disease (HD).Methods: this study was conducted on fForty males (40) confirmed were enrolled research.,theAll subjected to underwent following: full Hhistory taking, International index (IIEF-5), Beck anxiety scale depression scale.Results: About 77.5% our had dysfunction, 87.5% showed disorders.while While 52.5% depressive disorders and, 27.5% abnormal free testosterone levels.There A...

Introduction: Among the reasons for patient dissatisfaction following penile prosthesis implantation (PPI) is decreased length, possibly due to as per flaccid stretched which shorter than erect length. Aim of Study:To examine safety sizing implant length state, and its efficacy in enhancing satisfaction, by evaluating outcome patients with refractory ischemic priapism operated upon early enough before fibrosis sets in.Patients Methods: Patients study were recruited past 2 years.Nineteen...

Abstract Background: investigate the prevalence and The related factors between two types of premature ejaculation (lifelong PE[LPE], acquired PE [APE] in men atherosclerosis. Methods : One hundred patients complaining 100 control subjects were enrolled this prospective study.All cases underwent a full medical history Clinical examination.Blood pressure,serum lipid profile, testosterone,and Body mass index (BMI) measured.The Arabic (AIPE) self-estimated (IELT) Intravaginal latency time was...

Objective: To evaluate sexual functions of patients with erectile dysfunction (ED) and their female partners. Methods: A total 90 consecutive ED who received different therapies partners controls were divided into four groups. All participants evaluated by the 15-item international index function Arabic version (Ar-FSFI). Results: sildenafil demonstrated significant improvements compared to baseline. Their did not demonstrate in frequency pain during vaginal penetration (3.86 ± 0.58, 3.93...

Climate change is considered as one of the biggest threats to coral reefs in next 100 years. The most significant impact climate would be rise global seawater temperature. A critical turning point which determines fate depends on how corals and their associated algae respond Symbiotic plasticity may help survive such environmental threats. zooxanthella Symbiodinium classified into nine clades (A – I), six are known symbionts. As reaction thermal stress, symbionts lost host by several...