The shipping industry is becoming increasingly aware of its environmental responsibilities in the long-term. In 2018, International Maritime Organization (IMO) pledged to reduce greenhouse gas (GHG) emissions by at least 50% year 2050 as compared with a baseline value from 2008. Ammonia has been regarded one potential carbon-free fuels for ships based on these issues. this paper, we propose four propulsion systems 2500 Twenty-foot Equivalent Unit (TEU) container feeder ship. All proposed are...

With the proliferation of online video, measuring quality experience (QoE) has become a pivotal aspect for analysis today's over-the-top (OTT) video streaming. To monitor QoE, we introduce YouSlow that can detect various playback events (e.g., start-up latency, rebufferings and bitrate changes) from players while is being played. Using YouSlow, have collected more than 400,000 YouTube views 100 countries. We measured impact these on abandonment found incur rates six times higher mostly...

Today's over the top (OTT) video service providers take advantage of content distribution networks (CDNs) and adaptive bitrate (ABR) streaming where a player adjusts resolutions based on end-to-end network conditions. Although mechanisms are useful to improve user-perceived quality, they do not resolve root causes congestion problems. To pinpoint bottleneck quality-of-experience (QoE), we leverage software-defined networking (SDN) platform from OTT provider's point view. Our proposed SDN...

This study presents a hybrid power system comprising fuel cell (FC) and lithium-ion battery (LIB) for liquid hydrogen (LH2) carriers, which is expected to increase globally due the production cost gap of green between renewable-rich renewable-poor countries. The LH2 carrier has key challenge in handling inevitably considerable boil-off (BOH). As target ship 50,000 m3 with rate (BOR) 0.4% per day, this employs an optimization tool determine economic dispatch FC LIB aimed at minimizing...

OATP1B3 is a member of the OATP (organic anion transporting polypeptides) superfamily, responsible for mediating transport numerous endogenous and xenobiotic substances. Although initially reported to be exclusively expressed in liver, several studies that frequently multiple types cancers may associated with differing clinical outcomes. However, detailed investigation on expression function protein cancer has been lacking. In this study, we confirmed colon pancreatic cells express variant...

The primary electric power system of ships has been based on the alternating current (AC) for a long time. However, marine engineers started to question efficiency AC-grid system, which was previously taken granted and attempted find more efficient eco-friendly distribution system. Following this trend in industry, direct (DC) adopted combined with AC-grid. In regard, paper presents technical, economic, environmental benefits DC-grid applications. Ships that have already applied or plan...

Globally, gastric ulcer is a vital health hazard for human. Rabdosia inflexa (RI) has been used in traditional medicine inflammatory diseases. The present study aimed to investigate the protective effect and related molecular mechanism of RI using lipopolysaccharide (LPS)-induced inflammation RAW 246.7 cells HCl/EtOH-induced mice. We applied 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), nitric oxide (NO), reactive oxygen species (ROS), histopathology, malondialdehyde...

SEDL is an evolutionarily highly conserved protein in eukaryotic organisms. Deletions or point mutations the<i>SEDL</i> gene are responsible for the genetic disease spondyloepiphyseal dysplasia tarda (SEDT), X-linked skeletal disorder. has been identified as a component of transport particle (TRAPP), critically involved endoplasmic reticulum-to-Golgi vesicle transport. Herein, we report 2.4 Å resolution structure SEDL, which reveals unexpected similarity to structures N-terminal regulatory...

Carfilzomib is a novel class of peptidyl epoxyketone proteasome inhibitor and has demonstrated promising activity in multiple clinical trials to treat patients with myeloma other types cancers. Here, we investigated molecular mechanisms underlying acquired resistance carfilzomib potential strategy restore cellular sensitivity carfilzomib. H23 DLD-1 cells (human lung colon adenocarcinoma cell lines) displayed marked cross-resistance YU-101, closely related inhibitor, paclitaxel, known...

Concerns about harmful exhaust emissions from ships have been an issue. Specifically, the at ports are most serious. This paper introduces a hybrid power system that combines conventional diesel generators with two different energy storage systems (ESSs) (lithium-ion batteries (LIB) and supercapacitors (SC)) focused on port operations of ships. To verify proposed system, bulk carrier four deck cranes is selected as target ship, each size (capacity) LIB SC determined based assumed demands....

Liquefied natural gas (LNG) is recognized as a preferable alternative fuel for ship owners, since it can substantially reduce harmful emissions to comply with stricter environmental regulations. The increasing number of LNG-fueled vessels has driven up the LNG bunkering (LNGBVs) well. A key issue LNGBVs boil-off (BOG) generation, especially huge amount BOG that generated during loading and unloading (bunkering) processes. This study proposes hybrid system combines conventional onboard...

This study presents the results of economic and environmental analysis for two types zero-emission ships (ZESs) that are receiving more attention to meet strengthened regulations. One ZES is using only energy storage system (All-ESS), other with fuel cell ESS hybrid (FC–ESS). The target ship a tug operating in South Korea, main parameters based on specific circumstances Korea. optimal capacity each proposed determined an optimization tool. total cost ship’s lifetime calculated analysis....

Adaptive bitrate (ABR) technologies are being widely used in today's popular HTTP-based video streaming such as YouTube and Netflix. Such a rate-switching algorithm embedded player is designed to improve quality-of-experience (QoE) by selecting an appropriate resolution based on the analysis of network conditions while playing. However, bad viewing experience often caused having difficulty estimating transit or client-side accurately. In order analyze ABR performance, we developed YouSlow,...

Ships entering designated emission control areas are required to reduce gases drastically, in accordance with international maritime organization regulations or local policies. In this regard, a hybrid power system, which is combination of conventional generators and lithium-ion batteries as type energy storage system (ESS), has been applied ships. However, concept focused on small-sized coastal ships, because they have short voyage time require high peak for time. And by extension, paper...

Mesoporous cobalt oxide (Co3O4) films were deposited on ITO coated glass substrates by electrodeposition from an aqueous CoSO4 solution using CTAB (cetyltrimethylammonium bromide) as the templating agent. The structures of synthesized characterized X-ray diffraction, and photoelectron spectroscopy. presence mesoporosity was confirmed transmission electron microscopy small angle diffraction analyses. mesoporous found to be strongly dependent deposition conditions, such voltage, time,...