A5100389103- Radiomics and Machine Learning in Medical Imaging
- Suicide and Self-Harm Studies
- Psychosomatic Disorders and Their Treatments
- MRI in cancer diagnosis
- Radiopharmaceutical Chemistry and Applications
- Corneal Surgery and Treatments
- Medical Imaging and Pathology Studies
- Advanced MRI Techniques and Applications
- Peptidase Inhibition and Analysis
- AI in cancer detection
- Medical Imaging Techniques and Applications
- Cancer-related gene regulation
- Genetics and Neurodevelopmental Disorders
- Monoclonal and Polyclonal Antibodies Research
- Extracellular vesicles in disease
- Cardiac Imaging and Diagnostics
- Bipolar Disorder and Treatment
- Epigenetics and DNA Methylation
- Corneal surgery and disorders
- Circular RNAs in diseases
- Advanced Neuroimaging Techniques and Applications
- Ultrasound Imaging and Elastography
- Advanced Computing and Algorithms
- Mindfulness and Compassion Interventions
- Digital Imaging for Blood Diseases
Binzhou Medical University
2025
First Affiliated Hospital of Hebei Medical University
2024
Southern Medical University
2024
Nanfang Hospital
2024
Nanchang University
2020-2024
Peking University
2007-2024
Sun Yat-sen University
2024
First Affiliated Hospital of Jiangxi Medical College
2024
Jiangxi Provincial People's Hospital
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2020-2024
Background Breast cancer is the most common malignant tumor in women and a quantitative contrast‐free method highly desirable for its diagnosis. Purpose To investigate performance of MRI differentiating from benign breast lesions to compare with Imaging Reporting Data System (BI‐RADS). Study Type Retrospective. Subjects Eighty patients (56 24 lesions). Field Strength/Sequence Diffusion‐weighted imaging (DWI) single‐shot echo planar sequence synthetic magnetic resonance image compilation...
Abstract Objective To explore relationship among self‐injury behavior, experiential avoidance, cognitive fusion, anxiety, and depression in Chinese adolescent patients with nonsuicidal (NSSI). Methods Cognitive fusion questionnaire (CFQ), Acceptance Action Questionnaire—2nd edition (AAQ‐II), behavior (ANSAQ), Hamilton Anxiety Scale (HAMA), Depression (HAMD) were used as research tools to investigate 120 subjects NSSI 130 healthy controls. Results The scores of CFQ AAQ‐II the group...
Abstract Background Tumor-associated macrophages are considered to be a major contributor affecting the development of tumors. Recently, numerous studies have shown that tumor cells were able educate their microenvironment by delivering significant amount exosomes, however, mechanism exosomes from PCa work in macrophage polarization remains obscure. Therefore, we sought determine whether blockade exosome generation GW4869, an inhibitor biogenesis, would impede differentiating into M2 cells....
On-bead screening of one-bead-one-compound (OBOC) libraries provides a powerful method for the rapid identification active compounds against molecular or cellular targets. However, on-bead is susceptible to interference from nonspecific binding, which results in biased data and false positives. In this work, we have found that major source binding derived high ligand loading on library beads, permits macromolecular target (e.g., protein) simultaneously interact with multiple ligands bead...
Based on non-contrast-enhanced (NCE)/contrast-enhanced (CE) computed tomography (CT) images, we try to identify a combined-radiomics model and evaluate its predictive capacity regarding response anti-PD1 immunotherapy of patients with non-small-cell lung cancer (NSCLC).131 NSCLC undergoing were retrospectively enrolled from 7 institutions. Using largest lesion (LL) target lesions (TL) approaches, performed radiomics analysis based pretreatment NCE-CT (NCE-radiomics) CE-CT images...
Introduction Autism spectrum disorder (ASD) is often associated with sleep disorders, although the neurophysiological reasons behind these issues are poorly understood. In this cross-sectional study, functional near-infrared spectroscopy (fNIRS) was used to compare differences in brain connectivity (FC) children ASD and disorders those that not complicated by disorders. Methods A total of 88 (4–9 years old, either sex) were included study. The divided into three groups: (ASD group; n = 29),...
The deoxyglucose dithiocarbamate (DGDTC) was radiolabeled with 99m Tc(V)‐glucoheptonate (GH), for the potential use as radiopharmaceuticals tumor imaging. For labeling, TcO‐DGDTC prepared by ligand‐exchange reaction Tc‐GH. radiochemical purity of complex over 90% thin‐layer chromatography and high‐performance liquid chromatography, without any notable decomposition at room temperature a period 6 h. Its partition coefficient indicated that it hydrophilic complex. occured neutral condition...
Fast and automated reconstruction of retinal hyperreflective foci (HRF) is great importance for many eye-related disease understanding. In this paper, we introduced a new framework, driven by recent advances in deep learning to automatically extract 12 three-dimensional parameters from the segmented optical coherence tomography (OCT).Unlike traditional convolutional neural networks, which struggle with long-range feature correlations, introduce spatial channel attention module within...
<sup>99m</sup>TcO-N4IPDTC was prepared from a kit without the need for purification and would be promising hypoxia imaging agent.
Currently, a popular strategy for designing novel radioprobes as bone‐imaging agents is based on the concept of bifunctional radiopharmaceuticals. Considering dithiocarbamate ligand can act suitable linking agent to attach technetium‐99m ( 99m Tc) corresponding target molecules, in this study, alendronate ALNDTC ) was synthesized and radiolabeled with [ Tc≡N] 2+ core by exchange reaction produce TcN‐ complex, potential use probe bone imaging. The radiochemical purity complex over 90%. stable...
Abstract Rabbit corneal endothelial cells are frequently used in pharmacological experiments and useful for transplant experiments. We performed the present study to analyze effect of conditioned medium (CM) derived from human umbilical cord mesenchymal stem (HUMSCs) on growth rabbit (RCECs) establish a program expansion RCECs vitro. were cultured using CM HUMSCs (HUMSCs‐CM) The proliferation ability presence HUMSCs‐CM was evaluated by conducting...
Purpose. Corneal endothelial cells are usually exposed to shear stress caused by the aqueous humour, which is similar exposure of vascular blood flow. However, effect fluid on corneal still poorly understood. The purpose this study was explore whether that results from humour influences cells. Methods. An in vitro model established generate flow cells, and after two levels for different durations investigated. mRNA protein expression endothelium-related markers rabbit evaluated real-time PCR...
Abstract Objective: Rapid restoration of corneal epithelium integrity after injury is particularly important for preserving transparency and vision. Mesenchymal stem cells (MSCs) can be taken into account as the promising regenerative therapeutics improvement wound healing processes based on variety effective components. The extracellular vesicles form MSCs, especially exosomes, has been considered paracrine mediators though transferring microRNAs recipient cell. This study investigated...