- Systemic Lupus Erythematosus Research
- Pregnancy and Medication Impact
- Liver Diseases and Immunity
- Atherosclerosis and Cardiovascular Diseases
- Monoclonal and Polyclonal Antibodies Research
- Inflammatory Myopathies and Dermatomyositis
- T-cell and B-cell Immunology
- Reproductive System and Pregnancy
- Lymphoma Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Eosinophilic Disorders and Syndromes
- Muscle Physiology and Disorders
- Pregnancy and preeclampsia studies
- Diabetes and associated disorders
- Dermatological and Skeletal Disorders
- Genetic Neurodegenerative Diseases
Hospital de Especialidades
2012-2020
Centro Médico Nacional La Raza
2012-2020
Mexican Social Security Institute
2013-2020
Universidad Nacional Autónoma de México
2015
Center for Rheumatology
2012
Abstract Objectives To compare clinical characteristics, including the frequency of cutaneous, extramuscular manifestations and malignancy, between adults with anti-synthetase syndrome (ASyS) DM. Methods Using data regarding from MYONET registry, a cohort DM patients anti-Mi2/-TIF1γ/-NXP2/-SAE/-MDA5 autoantibodies, ASyS anti-tRNA synthetase autoantibodies (anti-Jo1/-PL7/-PL12/-OJ/-EJ/-Zo/-KS) were identified. Patients sine dermatitis or discordant dual autoantibody specificities excluded....
Abstract Introduction Several factors have been associated with the development of preeclampsia in women systemic lupus erythematosus (SLE). Objective To identify risk patients SLE and its impact on fetal outcomes. Patients methods We studied a prospective cohort pregnancies from January 2009 to December 2018. Demographic, clinical, serological drug use characteristics were compared between who developed those did not, as well main neonatal An adjusted logistic regression analysis was...
Antinuclear autoantibodies (ANA) targeting the dense fine speckled antigen DFS70, also known as lens epithelium-derived growth factor p75 (LEDGF/p75), are attracting attention due to their low frequency in systemic rheumatic diseases but increased clinical laboratory referrals and healthy individuals (HI). These ANA specifically recognize stress protein DFS70/LEDGFp75, implicated cancer, HIV-AIDS, inflammation. While has been investigated various ethnic populations, there is little...
The aim of this study was to estimate the impact haematological manifestations systemic lupus erythematosus (SLE) on mortality in hospitalized patients. For that purpose a case–control patients medical referral centre from January 2009 December 2014 performed. analysis, for any activity SLE ( n = 103) were compared with other or complications treatment 206). Taking as variable outcome hospital death, an analysis potential associated factors most common manifestation thrombocytopenia (63.1%),...
Myositis specific autoantibodies are associated with unique clinical subsets and useful biomarkers in polymyositis/dermatomyositis (PM/DM). A 120 kD protein recognized by certain patients DM was identified features of this specificity were characterized. The a prototype serum purified mass spectrometry immunological methods. Autoantibody to screened sera from 2,356 various diagnoses four countries, including 254 PM/DM, immunoprecipitation 35S-methionine labeled K562 cell extracts. Clinical...
<h3>Background</h3> Several prognostic factors have been described in lupus nephritis, which vary depending on the population studied. Few studies examined these relation to different stages of treatment. <h3>Objectives</h3> To identify associated with response induction therapy LN according <h3>Methods</h3> We performed a retrospective case-control study nested cohort patients systemic erythematosus (SLE) biopsy-proven WHO, period from January 2001 December 2008. All received remission and...