A5100368507- Lymphoma Diagnosis and Treatment
- Immune Cell Function and Interaction
- Cardiac, Anesthesia and Surgical Outcomes
- GABA and Rice Research
- Glioma Diagnosis and Treatment
- Selenium in Biological Systems
- Mercury impact and mitigation studies
- CNS Lymphoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Pulmonary Hypertension Research and Treatments
- Esophageal Cancer Research and Treatment
- Viral-associated cancers and disorders
- Extracellular vesicles in disease
- Intracranial Aneurysms: Treatment and Complications
- Advanced Chemical Sensor Technologies
- Vascular Malformations Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Anesthesia and Pain Management
- Cancer Immunotherapy and Biomarkers
- Brain Metastases and Treatment
- Heterotopic Ossification and Related Conditions
- Facial Nerve Paralysis Treatment and Research
- Fluoride Effects and Removal
- Trigeminal Neuralgia and Treatments
- Autophagy in Disease and Therapy
XinHua Hospital
2016-2025
Shanghai Jiao Tong University
2016-2025
Shandong First Medical University
2024-2025
Shandong Tumor Hospital
2024-2025
Southwest Medical University
2024-2025
Northwest University
2024
Sun Yat-sen University
2023
Sun Yat-sen University Cancer Center
2023
China Medical University
2022
Xuzhou Medical College
2017-2020
This study aimed to explore the prognostic value of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) metabolic parameters immune organs and hematological immune-related markers for patients with locally advanced cervical cancer (LACC) undergoing concurrent chemoradiotherapy (CCRT), establish nomograms based on these potential biomarkers. A total 180 LACC CCRT were retrospectively reviewed randomly divided into training validation groups at a...
The common drugs used for the treatment of Newly Diagnosed Multiple Myeloma (NDMM) include bortezomib and lenalidomide, but adverse effects lenalidomide cannot be ignored, especially when it is in initial therapy. This retrospective study evaluated efficacy safety a modified DVD regimen (pegylated liposomal doxorubicin, bortezomib, dexamethasone) followed by NDMM. A total 40 NDMM patients were treated with reduced dose pegylated doxorubicin (20 mg/m2) on day 1, subcutaneous (1.3 days 4, 8,...
Aging leads to progressive decline in the functions of cells, tissues, and organs, severely affecting muscle performance overall health, highlighting urgent need for effective therapeutic agents. This study investigated antiaging properties tricin, a flavonoid abundant grains, using biological models, including human fibroblasts, Caenorhabditis elegans (C. elegans), mice. Tricin significantly alleviated senescent phenotype fibroblasts induced by D-galactose (D-gal), doxorubicin, replicative...
Radiation-induced thrombocytopenia (RIT) is a serious complication of cancer radiotherapy, for which therapeutic options are limited. This study investigates wedelolactone (WED), metabolite botanical drug, as potential treatment RIT. In vitro experiments were conducted using Meg-01 and K562 cell lines to evaluate the effects WED on megakaryocyte differentiation maturation. Flow cytometry phalloidin staining employed assess expression megakaryocyte-specific markers CD41 CD61, well nuclear...
With the development of painless diagnosis and treatment, remifentanil, a synthetic opioid agonist, is increasingly used in gastroscopy for its rapid, short-term, potent analgesic effect. However, dosage remifentanil endoscopy unclear. Index consciousness (IOC) new anesthesia depth-monitoring indicator that can be divided into index 1 (IOC1) 2 (IOC2); IOC1 estimating patient's sedation state, whereas IOC2 reflects depth. We hypothesized combining with monitoring may helpful to identify an...
Summary Early‐stage natural killer/T‐cell lymphoma (NK/TCL) patients usually receive a combination of chemotherapy and radiotherapy, but the optimal treatment approach has not yet been established. This study aimed to investigate efficacy safety profile novel regimen sandwiched radiotherapy in early‐stage NK/TCL. Patients with newly diagnosed stage IE/IIE disease were eligible. initially treated two courses GELAD (gemcitabine 1·0 g/m 2 day 1, etoposide 60 mg/m days 1–3, pegaspargase 2000...
Abstract Background The spleen plays an important role in systemic antitumor immune response, but whether imaging features have predictive effect for prognosis and status was unknown. aim of this study to investigate computed tomography (CT)‐based radiomics predict the patients with esophageal squamous cell carcinoma (ESCC) underwent definitive radiotherapy (dRT) try find its association immunity. Methods This retrospective included 201 ESCC who received dRT. Patients were randomly divided...
Optimal treatment strategies for natural killer/T-cell lymphoma (NKTCL) patients with stage IV disease have not been well defined. In this prospective phase 2 study, we evaluated the using MEDA (methotrexate, etoposide, dexamethasone and pegaspargase) as induction chemotherapy autologous hematopoietic stem cell transplantation (Auto-HSCT) consolidation. Patients without prior L-asparaginase-based were eligible. Four cycles of administered treatment. complete response (CR, necessary to...
We hypothesized that posterior quadratus lumborum block would reduce postoperative opioid consumption and improve the quality of recovery in patients undergoing sutureless laparoscopic partial nephrectomy.The study included 60 patients, ages 18-65 with American Society Anesthesiologists scores I-II scheduled for elective nephrectomy. Before general anesthesia, participating were randomly allocated to receive a 30-ml injection muscle either 0.375% ropivacaine (n = 30) or normal saline 30)....
To explore the effect of dimethyl 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DCDDP) on pulmonary hypertension (PH) induced by monocrotaline (MCT), parameters hemodynamics, contents endothelin-like immunoreactivity, nitric oxide (NO), malondialdehyde, and superoxide dismutase in plasma homogenate were measured. DCDDP was administered 5, 50, 500 μg · kg −1 day ip doses, once a for 28 days. The antiserotonin investigated using immunohistochemistry, image analysis,...
Stents are mechanical devices used to provide support clocked blood vessels in different parts of the human body. Coronary stents that implanted coronary artery provides heart [1]. development began early 1980s after a new procedure called percutaneous intervention (PCI) was successful opening arteries [2] but acute vessel closure and restenosis were higher patients, who subjected this [3]. Sigwart et al. [4] described 1987 first nonrandomized data about Wallstent [5]. Even though U.S., many...