Tian Tian

ORCID: 0000-0003-4180-3013
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About
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Research Areas
  • Anesthesia and Pain Management
  • Nausea and vomiting management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Sedative Agents
  • Airway Management and Intubation Techniques
  • Spine and Intervertebral Disc Pathology
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Neurotoxicity Research
  • Pain Management and Opioid Use
  • Tracheal and airway disorders
  • Shoulder Injury and Treatment
  • Cardiac Arrest and Resuscitation
  • Obstructive Sleep Apnea Research
  • Spinal Fractures and Fixation Techniques
  • Acute Kidney Injury Research
  • Respiratory Support and Mechanisms
  • Hemodynamic Monitoring and Therapy
  • Thermal Regulation in Medicine
  • Reconstructive Surgery and Microvascular Techniques
  • Helicobacter pylori-related gastroenterology studies
  • Pediatric Pain Management Techniques
  • Hip and Femur Fractures
  • Congenital Diaphragmatic Hernia Studies
  • Diabetic Foot Ulcer Assessment and Management
  • Minimally Invasive Surgical Techniques

Beijing Friendship Hospital
2021-2025

Capital Medical University
2001-2025

Yunnan University of Traditional Chinese Medicine
2025

Beijing Chao-Yang Hospital
2018-2024

Beijing YouAn Hospital
2023-2024

West China Second University Hospital of Sichuan University
2024

Systems, Applications & Products in Data Processing (United Kingdom)
2024

Sengkang General Hospital
2024

Versus Arthritis
2024

Sichuan University
2024

Gallic acid (3,4,5-trihydroxybenzoic acid, GA) is a phenolic compound found in many medicinal plants traditionally used China or patent medicine such as Feiyangchangweiyan capsule (FY capsule) for the treatment of gastrointestinal diseases decades. However, evidence gastroprotective effect GA deficient and pharmacological mechanisms remain limited. The present investigation was initiated to demonstrate understand potential underlying mechanism on ethanol-induced gastric ulcer rats. Gastric...

10.1016/j.biopha.2020.110075 article EN Biomedicine & Pharmacotherapy 2020-03-13

Evidence suggests that C-reactive protein (CRP), procalcitonin (PCT), and immune cells can predict sepsis severity in adult patients. However, the specific values of these indicators are not consistent predicting prognosis.A retrospective study analyzed medical records 194 patients based on concept 2016 (Sepsis 3.0) from January 2017 to December 2019. A comparative analysis inflammatory factors associated with survival non-survival group was performed. The concentrations CRP PCT,...

10.1186/s12873-021-00477-5 article EN cc-by BMC Emergency Medicine 2021-07-07

To observe the protective effects of dexmedetomidine (Dex) postconditioning on myocardial ischemia/reperfusion injury (IRI) and to explore its potential molecular mechanisms.One-hundred forty-seven male Sprague-Dawley rats were randomly divided into five groups receiving different treatments: Sham, (I/R), Dex, Brusatol, Dex + Brusatol. By in vivo rat model IRI, cardioprotective evaluated by assessing serum CK-MB cTnI levels, HE Tunel staining infarct size. Furthermore, oxidative...

10.1080/13510002.2022.2158526 article EN cc-by Redox Report 2023-02-04

Measurement of the posterior tibial slope (PTS) angle has important applications in total knee replacement surgery, high osteotomy, and anterior cruciate ligament reconstruction. This study aimed to determine mean PTS joints healthy Chinese adults, provide data guide surgery China.A retrospective analysis 1257 (n = 1233, 50.4% male) plain X-ray films participants aged 25-59 years was performed. The picture archiving communication system used for measurement. defined as between vertical line...

10.1186/s12891-022-05319-4 article EN cc-by BMC Musculoskeletal Disorders 2022-04-26

Parkin-related mitophagy is vital for endothelial cell viability and the development of atherosclerosis, although upstream regulatory factor underlying Parkin-mediated in apoptosis atherosclerosis progression remains unknown. In present study, we demonstrated that nuclear receptor subfamily 4 group A member 1 (NR4A1) actually expressed aortic cells (AECs) under oxidized low-density lipoprotein (ox-LDL) treatment vitro or isolated from high-fat treated mice vivo. Higher NR4A1 levels were...

10.1007/s12192-018-0886-1 article EN cc-by-nc-nd Cell Stress and Chaperones 2018-02-22

Abstract Atherosclerosis (AS) is a major pathogenic factor in patients with cardiovascular diseases, and endothelial dysfunction (ED) plays primary role the occurrence development of AS. In our study, we attempted to evaluate phosphatase tensin homolog (PTEN) cell apoptosis under oxidized low‐density lipoprotein (ox‐LDL) stimulation identify associated mechanisms. The results study demonstrated that ox‐LDL induced human umbilical vein (HUVEC) death via mitochondrial apoptosis, as evidenced...

10.1002/jcp.29366 article EN Journal of Cellular Physiology 2019-10-25

Objectives To develop a CT-based radiomics model and combined for preoperatively discriminating infiltrative renal cell carcinoma (RCC) pyelocaliceal upper urinary tract urothelial (UTUC), which invades the parenchyma. Materials methods Eighty patients (37 pathologically proven RCCs 43 UTUCs) were retrospectively enrolled randomly divided into training set (n = 56) testing 24) at ratio of 7:3. Traditional CT imaging characteristics in portal venous phase collected by two radiologists (SPH...

10.3389/fonc.2023.1244585 article EN cc-by Frontiers in Oncology 2024-01-18

To establish and optimize the venous thromboembolism(VTE), whole process prevention treatment information system based on electronic medical record system. Improving convenience efficiency of VTE control management to achieve continuous, dynamic, effective monitoring other advantages management, reduce incidence improve quality safety. Beijing Friendship Hospital established a hospital in 2020. Through it explores ways prevent manage hospitalized patients. This study took all patients from...

10.3760/cma.j.cn112150-20240926-00777 article EN PubMed 2025-03-06

Objective: To investigate the pregnancy outcomes after transvaginal or transabdominal fetal reduction for higher‐order multifetal pregnancies with four more fetuses. Methods: This retrospective study included 102 patients ovulation induction. The underwent in Reproductive Medical Center of Peking University Third Hospital from January 2000 to December 2020. Methods and reduction. Pregnancy different methods were assessed, including live birth rate, miscarriage preterm labor low birthweight...

10.1155/ijcp/2512443 article EN cc-by International Journal of Clinical Practice 2025-01-01

Background Neonatal infections, particularly neonatal sepsis, remain significant contributors to morbidity and mortality in pediatrics. This study aims provide data support for health authorities control infections by analyzing the burden of sepsis other infectious (NSNIs) globally trends their risk factors. Methods is based on Global Burden Disease (GBD) database, reviewing diseases from 1990 2021 at global, regional, national levels. Descriptive statistics Joinpoint regression analyses...

10.3389/fmed.2025.1536948 article EN cc-by Frontiers in Medicine 2025-04-04

<title>Abstract</title> Background Proximal humeral fractures (PHFs) are common in elderly individuals, often resulting from osteoporosis and falls. Surgical intervention is required for displaced to restore shoulder function. This study compares the Modified Minimally Invasive Parachute Technique Intermuscular Gap Approach management of PHFs. Objective To compare clinical outcomes, including surgical efficiency, complication rates, functional recovery, radiographic healing, between two...

10.21203/rs.3.rs-6261905/v1 preprint EN Research Square (Research Square) 2025-05-08

Atherosclerosis develops as a consequence of inflammation and cell senescence. In critical factors involved in the atherosclerotic changes, reactive oxygen species (ROS) generation is considered leading cause. While NADPH oxidases, particularly NOX2, are main sources ROS, how they regulated disease incompletely understood. addition, caveolae, membrane structure implicated oxLDL deposition under vascular endothelia, oxLDL-mediated ROS production remains mostly elusive. We report here that...

10.1042/bsr20180283 article EN cc-by Bioscience Reports 2018-04-25

Background: Patients undergoing carotid endarterectomy (CEA) for severe stenosis are vulnerable to postoperative delirium, a complication frequently associated with poor outcome. This study investigated the impact of processed electroencephalogram (EEG)-guided anesthesia management on incidence delirium in patients CEA. Methods: single-center, prospective, randomized clinical trial 255 receiving CEA under general compared outcomes patient state index (PSI) monitoring [SEDLine Brain Function...

10.3389/fneur.2021.666814 article EN cc-by Frontiers in Neurology 2021-07-12

Most topical medications need a long time to penetrate into the skin owing stratum corneum (SC) barrier. The fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser has ability disrupt SC and assist in delivery of drugs skin. This study was intended determine whether pretreatment with painless Er:YAG could transdermal anesthesia.In 22 healthy female subjects, three 4 × 3 cm regions on right forearm were randomized to: plus lidocaine cream (Group LaserAnes), sham irradiation anesthesia...

10.1080/14764172.2016.1197404 article EN Journal of Cosmetic and Laser Therapy 2016-07-15

This study was conducted with the intent to develop and validate a radiomic model capable of predicting intrahepatic cholangiocarcinoma (ICC) in patients lithiasis (IHL) complicated by imagologically diagnosed mass (IM).A developed training cohort 96 IHL-IM from January 2005 July 2019. Radiomic characteristics were obtained arterial-phase computed tomography (CT) scans. The score (rad-score), based on features, built logistic regression after using least absolute shrinkage selection operator...

10.3389/fonc.2020.598253 article EN cc-by Frontiers in Oncology 2021-01-07
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