A5048499160- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Substance Abuse Treatment and Outcomes
- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Health Policy Implementation Science
- Adolescent Sexual and Reproductive Health
- Opioid Use Disorder Treatment
- Cannabis and Cannabinoid Research
- Adolescent and Pediatric Healthcare
- Community Health and Development
- Schizophrenia research and treatment
- Smoking Behavior and Cessation
- Vaccine Coverage and Hesitancy
- Mental Health Treatment and Access
- Public Health Policies and Education
- Mental Health and Patient Involvement
- Behavioral Health and Interventions
- Law and Political Science
- Family Caregiving in Mental Illness
- Occupational exposure and asthma
- Prenatal Substance Exposure Effects
- Forensic Toxicology and Drug Analysis
- Communication in Education and Healthcare
University of California, San Francisco
2012-2024
San Francisco General Hospital
2005-2022
University of San Francisco
2017
Seattle University
2013
University of California System
2012
Kantonsspital Baselland Standort Bruderholz
2008
Kent State University
1987-1990
OBJECTIVES. This study examined hormonal contraceptive use and pregnancy in urban Rwandan women, following human immunodeficiency virus (HIV) antibody testing counseling. METHODS. A sample of 1458 childbearing women aged 18 to 35 years was tested followed for 2 years. RESULTS. At enrollment, 17% 998 HIV-negative 11% 460 HIV-positive were pregnant, vs 23%, respectively, using contraceptives. One year later, half the one third hormonal-contraceptive users had discontinued use. The 2-year...
Harm reduction approaches endeavor to assist individuals with avoiding the most detrimental consequences of risk taking behaviors, but limited research has documented outcomes harm substance abuse treatment. In total, 211 methamphetamine-using men who have sex (MSM) enrolled in two outcome studies treatment programs that were implementing an evidence-based, cognitive-behavioral intervention (i.e., Matrix Model) from a perspective. Study 1 (N = 123) examined changes self-reported use,...
Background: Substance use and mental health are two barriers to engagement in care antiretroviral therapy (ART) adherence among youth young adults living with HIV (YLWH). The consequences of suboptimal YLWH increased risk transmission a future generation immunodeficient drug-resistant virus. Methods: Youth Telehealth Texting for Engagement Care (Y2TEC) study was pilot randomized crossover trial that examined the feasibility acceptability novel video-counseling series accompanying text...
This research was conducted at a Substance Abuse Forum designed to address local community needs by focusing on Evidence-Based Practices (EBPs) in addiction treatment. The purpose of the study assess substance abuse treatment professionals' readiness adopt EBPs, experience with and attitudes toward as well agency support for EBPs. A total 119 providers completed pre-test measures, 82% post-test. Eighty-three percent participants reported using some EBPs past year, 75% currently Participants...
Disparities in HIV treatment outcomes among youth living with (YLWH) present a challenge for ending the epidemic. Antiretroviral therapy (ART) adherence can be impacted by comorbidities such as mental health and substance use. Technology use has shown promise increasing access to services. Using mixed-methods approach, we conducted formative research describe relationship between health, use, medication 18–29 year-old YLWH, explored technology an approach supporting these Among 101 ART was...
Individuals with a substance use disorder (SUD) are at significantly higher risk for coronavirus disease-19 (COVID-19) and have rates of COVID-19 related hospitalization death than those without SUD. This study assessed vaccine trust, transmission awareness, protective behaviors, effects on mental health smoking among sample clients in California residential SUD treatment programs identified factors associated trust.A multi-site (n = 265) completed cross-sectional survey. Multivariable...
Objective: The study focuses on whether substance abuse patients who enter a community residential facility (CRF) after discharge from inpatient care obtain more outpatient mental health and have lower readmission rates than comparable discharged directly to the community. Method: A national sample of (N = 5,176; 99% men) referred CRFs is compared matched Results: Compared with controls, CRF were likely aftercare obtained intensive care. Patients longer episodes had 6-month 1-year dropped...
Objective: Alcohol abuse occurs frequently in those with human immunodeficiency virus (HIV) infection. has been linked to poor response HIV treatment and more rapid progression of HIV. One possible contributor such observations is drug interactions between alcohol antiretroviral (ARV) medications. This study examined therapies (ARTs) containing either efavirenz or ritonavir alcohol. Methods: Human virus–infected individuals not currently receiving ARTs participated a randomized,...
Background. This study examined drug interactions between buprenorphine, a partial opioid agonist used for dependence treatment and pain management, the protease inhibitors (PIs) darunavir-ritonavir fosamprenavir-ritonavir.
Alcohol abuse has been associated with HIV/AIDS progression, but the effects of HIV infection and treatment on alcohol exposure have not explored to date. This pilot study examines relationship untreated blood concentrations (BAC) relative BAC after initiation antiretroviral therapy (ART).Fifteen volunteers participated in 2 sets or placebo administration studies before ART. Oral (1 g/kg) was administered, participants were followed for pharmacokinetics, subjective responses, cognitive over...
Youth and young adults living with HIV (YLWH) experience worse clinical outcomes than high rates of behavioural health challenges that impact their engagement in care adherence to antiretroviral therapy. This study the San Francisco Bay area aims evaluate feasibility, acceptability preliminary a 12-session telehealth counselling series provided 80 YLWH, including education, motivational enhancement problem-solving around care, mental health, substance use other challenges. Findings will...
This study examined baseline gender differences among HIV-positive methadone maintenance outpatients currently prescribed antiretroviral medications. Participants were enrolled in a larger clinical trial, which included 4-week observation period using electronic monitors to track medication adherence. Contrary previous literature, no significant detected between men (n = 42) and women 36) on adherence or depression. Both groups showed remarkably poor during (M 56% of doses taken time), high...
Background and Objectives Alcohol abuse complicates treatment of HIV disease is linked to poor outcomes. pharmacotherapies, including disulfiram (DIS), are infrequently utilized in co‐occurring alcohol use disorders possibly related concerns about drug interactions between antiretroviral (ARV) medications DIS. Method This pharmacokinetics study ( n = 40) examined the effect DIS on efavirenz (EFV), ritonavir (RTV), or atazanavir (ATV) these ARV metabolism aldehyde dehydrogenase (ALDH)...
Research demonstrates that injection drug users with HIV and/or AIDS have difficulty adhering to complex regimens of medications. Because the risk increased viral resistance associated irregular medication adherence, there is considerable clinical need assist clients who abuse substances in taking their antiretroviral medications on time and as directed. This article outlines intervention strategies improve adherence among are methadone maintenance. In this treatment manual, authors...