A5053515833- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Pneumonia and Respiratory Infections
- HIV/AIDS Impact and Responses
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Poverty, Education, and Child Welfare
- HIV, Drug Use, Sexual Risk
- Mobile Health and mHealth Applications
- ICT in Developing Communities
- HIV Research and Treatment
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- Patient Satisfaction in Healthcare
- Nosocomial Infections in ICU
- Infection Control and Ventilation
- Immunodeficiency and Autoimmune Disorders
- Helicobacter pylori-related gastroenterology studies
- COVID-19 Clinical Research Studies
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Healthcare Systems and Technology
- Global Maternal and Child Health
- COVID-19 and healthcare impacts
- Respiratory and Cough-Related Research
UK Health Security Agency
2023-2024
University of California, San Francisco
2016-2024
Public Health England
2020-2023
San Francisco AIDS Foundation
2016-2021
University of Bristol
2014
Nosocomial transmission of SARS-CoV-2 is a key concern, and evaluating the effect testing infection prevention control strategies essential for guiding policy in this area. Using within-hospital SEIR transition model typical English hospital, we estimate that between 9 March 2020 17 July approximately 20% infections inpatients, 73% healthcare workers (HCWs) were due to nosocomial transmission. Model results suggest placing suspected COVID-19 patients single rooms or bays has potential reduce...
Men who have sex with men (MSM) continue to be disproportionately impacted globally by the HIV epidemic. Studies suggest that self-testing (HIVST) is highly acceptable among MSM. Social network strategies increase testing are effective in reaching MSM, particularly MSM of color, may not otherwise test. We tested a social network-based strategy distribute HIVST kits African American (AAMSM) and Latino (LMSM).This study was conducted Alameda County, California, large, urban/suburban county an...
Abstract Nosocomial transmission of SARS-CoV-2 is a key concern and evaluating the effect testing infection prevention control strategies essential for guiding policy in this area. Using within-hospital SEIR transition model typical UK hospital, we predict that approximately 20% infections inpatients, 89% HCWs were due to nosocomial transmission. Placing suspected COVID-19 patients single rooms or bays has potential reduce hospital-acquired by up 80%. Periodic smaller on patient-burden but...
To achieve epidemic control of HIV by 2030, countries aim to meet 90-90-90 targets increase knowledge HIV-positive status, initiation antiretroviral therapy (ART) and viral suppression 2020. We assessed the progress towards these from 2014 2016 in South Africa as expanded treatment policies were introduced using population-representative surveys.Data collected January March August November Dr. Ruth Segomotsi Mompati District, North West Province. Each multi-stage cluster sample included 46...
Background: Substance use and mental health are two barriers to engagement in care antiretroviral therapy (ART) adherence among youth young adults living with HIV (YLWH). The consequences of suboptimal YLWH increased risk transmission a future generation immunodeficient drug-resistant virus. Methods: Youth Telehealth Texting for Engagement Care (Y2TEC) study was pilot randomized crossover trial that examined the feasibility acceptability novel video-counseling series accompanying text...
We distributed free OraQuick In-home HIV Test® kits to men at a gay bathhouse. Men were systematically selected receive coupon, which could be redeemed that night for an self-testing kit. Those offered the coupon asked take 11-item survey. About 181 received coupons, of whom 92 (51%) accepted and 61 (66%) coupon. who test completed survey (n = 53) more ethnically diverse (χ2 100.69, p < .01) than those receiving More half had not tested in past 6 months (50%) or never (7%). Importantly, last...
In countries with a high burden of HIV, such as South Africa, where the epidemic remains world's largest, improving early uptake and consistent adherence to antiretroviral therapy could bring substantial HIV prevention gains. However, patients are not linked or retained in care at rates needed curtail epidemic. Two strategies that have demonstrated potential stem losses along cascade sub-Saharan African context use text messaging short message service (SMS) peer-navigation services. We...
Few interventions have demonstrated improved retention in care for people living with HIV (PLHIV) sub-Saharan Africa. We tested the efficacy of two personal support - one using text messaging (SMS-only) and second pairing SMS peer navigation (SMS+PN) to improve over year.In a cluster randomized control trial (NCT# 02417233) North West Province, South Africa, we 17 government clinics three conditions: SMS-only (6), SMS+PN (7) or standard (SOC; 4). Participants at received appointment...
The prevalence of Clostridioides difficile infection (CDI) has been shown to vary markedly between European countries, both in hospitals and the community. Determining true proven challenging. Without systematic testing hospitals, unchecked transmission CDI can lead large outbreaks more susceptible cohorts. We investigate success surveillance control measures across Europe, by examining dynamics disease spread from community into a hospital setting. focus on national differences, such as...
Large proportions of people living with HIV (PLHIV) in sub-Saharan Africa are not linked to or retained care. There is a critical need for cost-effective interventions improve engagement and retention care inform optimal allocation resources.
Current research suggests that HIV self-screening (HIVSS) is a feasible and acceptable approach to increase testing among men who have sex with (MSM). However, few data are available shape policy around dissemination implementation. Gaps in knowledge include preferences for distribution of HIVSS kits, potential social harms benefits their use, how much test users would be willing pay the kits. The aim was inform recommendations optimise kits MSM South Africa (SA), where there high incidence...
Objective: We examine the efficacy of short message service (SMS) and SMS with peer navigation (SMS + PN) in improving linkage to HIV care initiation antiretroviral therapy (ART). Design: I-Care was a cluster randomized trial conducted primary facilities North West Province, South Africa. The study outcome retention care; this analysis includes secondary outcomes: ART initiation. Methods: Eighteen clinics were automated ( n = 7), tailored PN or standard (SOC; 4). Recently diagnosed adults...
Continuity of care is an attribute high-quality health systems and a necessary component chronic disease management. Assessment information for HIV in South Africa has identified substantial rates clinic transfer, much it undocumented. Understanding the reasons changing sources implications patient outcomes important informing policy responses.
Objectives To perform a model-based cost-effectiveness evaluation of rapid antimicrobial susceptibility test. Design A Markov model cohort hospital inpatients with urinary tract infection (with inpatient numbers based on national administrative data from 1 April 2017 to 31 March 2019). Setting Urinary infections (UTI) in acute National Health Service (NHS) Trusts England, the perspective NHS Healthcare system, at level. Participants simulated approximately 280 000 non-pregnant adult within...
The Research Chapter (Chapter 8) of the English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) Report 2021–2022 showcases research that has been undertaken is ongoing at UK Health Security Agency (UKHSA) in field healthcare-associated infections (HCAIs) antimicrobial resistance (AMR) from April 2021 to March 2022 [...]