- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Rabies epidemiology and control
- Mycobacterium research and diagnosis
- Reproductive tract infections research
- Bacterial Identification and Susceptibility Testing
- Infective Endocarditis Diagnosis and Management
- Immune Cell Function and Interaction
- Antimicrobial Resistance in Staphylococcus
- IL-33, ST2, and ILC Pathways
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Medicinal Plants and Bioactive Compounds
- Microbial infections and disease research
- COVID-19 Clinical Research Studies
- Immune responses and vaccinations
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- vaccines and immunoinformatics approaches
- Evolution and Genetic Dynamics
- Clostridium difficile and Clostridium perfringens research
- Birth, Development, and Health
Instituto de Agroquímica y Tecnología de Alimentos
2022-2025
Consejo Superior de Investigaciones Científicas
2022-2025
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2019-2022
Universitat de València
2019-2022
Institute for Integrative Systems Biology
2019-2022
Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is frequently used approach in microbial genomics. However, the choice may represent source errors that affect subsequent analyses such as detection nucleotide polymorphisms (SNPs) and phylogenetic inference. In this work, we evaluated effect on short-read sequence data from five clinically epidemiologically relevant bacteria ( Klebsiella pneumoniae , Legionella pneumophila Neisseria gonorrhoeae...
Early-life stress (ELS) has been robustly associated with a range of poor mental and physical health outcomes. Recent studies implicate the gut microbiome in stress-related mental, cardio-metabolic immune problems, but research on humans is scarce thus far often based small, selected samples, using retrospective reports ELS. We examined associations between ELS human large, population-based study children. was measured prospectively from birth to 10 years age 2,004 children Generation R...
Hypercaloric diets overactivate the intestinal immune system and disrupt microbiome epithelial cell functions, impairing glucose metabolism. The origins of this inflammatory cascade are poorly characterized. We investigated involvement proinflammatory group 1 innate lymphoid cells (ILC1s) in obesity progression metabolic disruption. In obese mice, we studied longitudinally ILC1s response to diet depletion address its role obesity. required for expansion pro-inflammatory macrophages ILC2s....
Wild birds have been suggested to be reservoirs of antimicrobial resistant and/or pathogenic Enterococcus faecalis (Efs) strains, but the scarcity studies and available sequences limit our understanding population structure species in these hosts. Here, we analysed clonal plasmid diversity 97 Efs isolates from wild migratory birds. We found a high diversity, with most sequence types (STs) being firstly described here, while others were other hosts including some predominant poultry. that...
Lactococcus garvieae is a well-known pathogen of fish, but rarely involved in infections humans and other mammals. In humans, the main clinical manifestation L. endocarditis usually related to ingestion contaminated food, such as undercooked fish shellfish. This study presents first complete genomic sequence strain isolated from patient with its comparative analysis genomes. human isolate contains circular chromosome 2 099 060 bp one plasmid 50 557 bp. comparison fully sequenced strains,...
Abstract Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is frequently used approach in microbial genomics. However, the choice may represent source errors that affect subsequent analyses such as detection nucleotide polymorphisms (SNPs) and phylogenetic inference. In this work, we evaluated effect on short-read sequence data from five clinically epidemiologically relevant bacteria ( Klebsiella pneumoniae , Legionella pneumophila Neisseria gonorrhoeae...