A5010691450- Peripheral Artery Disease Management
- Renal and Vascular Pathologies
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Cardiac Imaging and Diagnostics
- Diagnosis and Treatment of Venous Diseases
- Osteoarthritis Treatment and Mechanisms
- Peripheral Nerve Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Intraperitoneal and Appendiceal Malignancies
- Radiation Dose and Imaging
- Cancer Cells and Metastasis
- Nausea and vomiting management
- Coronary Interventions and Diagnostics
- Genetic and Kidney Cyst Diseases
- Aortic aneurysm repair treatments
- Advanced X-ray and CT Imaging
- Cancer Treatment and Pharmacology
- Anesthesia and Pain Management
- Cancer Research and Treatments
- Liver physiology and pathology
University Medical Centre Mannheim
2008-2025
Heidelberg University
2008-2025
University Hospital Heidelberg
2008-2025
Objective: This study was designed to demonstrate the predictive ability of quantitative indocyanine green (ICG) fluorescence angiography for short-term postoperative outcome, occurrence delayed graft function (DGF), and long-term survival. Summary Background Data: DGF is a relevant problem after kidney transplantation; sufficient microperfusion allograft crucial organ function. Fluorescence with ICG can serve as an intraoperative quality control microperfusion. Methods: prospective...
Abstract We investigated the therapeutic efficiency of sulfonate‐modified polyvinyl alcohol beads loaded with doxorubicin, irinotecan or mitoxantrone in vitro and vivo a model experimental peritoneal carcinomatosis (PC). In , cell proliferation was efficiently impaired by doxorubicin drug eluting bead (DEB) treatment while DEBs were less effective than. Irinotecan showed little effect for both free drug. Apoptosis not different between DEB form more apoptosis induction observed cells...
Different approaches to study liver regeneration in murine models have been proposed. We investigated the effect of different resection on damage and parameters mice.We compared technical aspect 2 most commonly used techniques 50% 70% resection. Liver damage, as determined by change serum alanine aminotransferase aspartate aminotransferase, well VEGF FGF-2 were analyzed at 6 time points. A postoperative vitality score was introduced.Cholestasis not observed for either technique. Both...
Background: Tunneled central venous catheters are commonly used for dialysis in patients without a functional permanent vascular access. In an emergent setting, non-tunneled, temporary catheter is often placed immediate dialysis. The most critical step the insertion venipuncture, which major cause longer intervention times and procedure-related adverse events. To avoid this when placing more tunneled catheter, exchange over previously one can be considered. paper, we present modified...
Delayed graft function (DGF) after renal transplantation is a relevant clinical problem affecting long-term organ function. The early detection of patients at risk crucial for postoperative monitoring and treatment algorithms. In this prospective cohort study, allograft perfusion was evaluated intraoperatively in 26 kidney recipients by visual formal assessment, duplex sonography, quantitative microperfusion assessment using O2C spectrometry ICG fluorescence angiography. tissue device...
Ureteral stenosis and urinary leakage are relevant problems after kidney transplantation. A standardized definition of ureterovesical anastomosis complications transplantation has not yet been established. This study was designed to demonstrate the predictive power quantitative indocyanine green (ICG) fluorescence angiography. bicentric historic cohort study, conducted between November 2015 December 2019, included 196 transplantations. The associations perfusion parameters near-infrared...
Background: Peripheral arterial disease (PAD), coronary artery (CAD) and carotid stenosis (CS) are robust predictors of mortality. The value individual vascular beds in polyvascular (PVD) to predict mortality patients with atherosclerotic burden is not clear. Therefore, we have examined the predictive PAD, CAD CS at intermediate high risk cardiovascular (CV) disease. Patients methods: In our retrospective observational study analyzed baseline data from Ludwigshafen Risk Cardiovascular Health...
Im OP-Ablauf nehmen wir Sie mit in die faszinierende Welt der Transplantationsmedizin: Ein OP-Team Universitätsmedizin Mannheim beschreibt Schritt für Schritt, wie eine Niere transplantiert wird.
The purpose of this study is to introduce and evaluate a modified surgical approach induce acute ischemia in mice that can be implemented most animal laboratories. Contrary the conventional for double ligation femoral artery (DLFA), smaller incision on right inguinal region was made expose proximal (FA) perform DLFA. Then, using 7-0 suture, dragged knee distal FA. Magnetic resonance imaging (MRI) bilateral hind limbs used detect FA occlusion after surgery. At 0, 1, 3, 5, 7 days surgery,...
Summary: Background: The femoropopliteal artery (FPA) plays a central role in diagnosing and treating peripheral arterial disease (PAD). FPA lesions are the most frequent cause of intermittent claudication, no other lower extremities is recanalised more frequently. Generally, ultrasound primary imaging tool PAD, particularly FPA. With development high-frame-rate technology addition to traditional modes, vector flow (VFI) has provided deeper haemodynamic insights when used carotid artery....
Background: The prevalence of peripheral arterial disease and the number revascularization procedures performed in symptomatic patients are steadily increasing. However, uncertainties remain regarding hemodynamic monitoring after prediction clinical outcomes. This study aimed to investigate parameters with a focus on microvasculature. Methods: prospective, single-center included 29 (15 intermittent claudication [IC] 14 chronic limb-threatening ischemia [CLTI]). Before procedure, addition...
Study objective The main of this study is to test the feasibility local anesthetic (LA) Mepivacaine 1% and sedation with Remifentanil as primary technique for insertion a peritoneal dialysis (PD) catheter, without need convert general anesthesia. Methods We analyzed 27 consecutive end-stage renal disease (ESRD) patients who underwent placement catheter at our center between March 2015 January 2019. procedures were all performed by or vascular surgeon, postoperative care follow-up conducted...
The purpose of this study is to introduce and evaluate a modified surgical approach induce acute ischemia in mice that can be implemented most animal laboratories. Contrary the conventional for double ligation femoral artery (DLFA), smaller incision on right inguinal region was made expose proximal (FA) perform DLFA. Then, using 7-0 suture, dragged knee distal FA. Magnetic resonance imaging (MRI) bilateral hind limbs used detect FA occlusion after surgery. At 0, 1, 3, 5, 7 days surgery,...