A5023607592- Exercise and Physiological Responses
- Cancer survivorship and care
- Adipose Tissue and Metabolism
- Nutrition and Health in Aging
- Music Therapy and Health
- Extracellular vesicles in disease
- Lymphatic System and Diseases
- Physical Activity and Health
- Childhood Cancer Survivors' Quality of Life
- Multiple Sclerosis Research Studies
- Muscle metabolism and nutrition
- Dialysis and Renal Disease Management
- Cardiovascular and exercise physiology
- Cancer-related cognitive impairment studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Heat shock proteins research
- Cancer Risks and Factors
- Cardiovascular Effects of Exercise
- Epigenetics and DNA Methylation
- Body Composition Measurement Techniques
- Children's Physical and Motor Development
- Bone health and osteoporosis research
- Diet and metabolism studies
- Circular RNAs in diseases
- Frailty in Older Adults
Foro Italico University of Rome
2016-2025
Magna Graecia University
2022-2023
Loughborough University
2023
Sapienza University of Rome
2014-2015
Regular physical activity is effective as prevention and treatment for different chronic conditions related to the ageing processes. In fact, a sedentary lifestyle has been linked worsening of cellular biomarkers such telomere length (TL) and/or specific epigenetic changes (e.g. DNA methylation), with increase propensity aging-related diseases premature death. Extending our previous findings, we aimed test hypothesis that 12 weeks low frequency, moderate intensity, explosive-type resistance...
The 2019 Coronavirus (COVID-19) outbreak caused home confinement, as well training and sport competitions withdrawals. prolonged inactivity impact, lack of in-person interactions among teammates-coaches, could negatively affect athletes. Total 1508 self-selected Italian athletes, 338 children (aged 10.52 ± 1.31), 499 adolescents 14.17 1.13), 671 adults 27.59 10.73), completed the Impact Event Scale (IES-8, IES-15, IES-R, respectively). Differences by gender, type (individual vs. team),...
Abstract Loss of balance and walking ability are two the primary impairments in multiple sclerosis (MS), which leads to loss autonomy, increased fatigue perception, disease severity patients. Physical activity has been shown ameliorate MS functional impairments, but there is limited evidence synergistic efficacy exercise training interventions that have both a resistance aerobic focus these We evaluated effect 12-wk combined intervention (resistance exercise) on balance, ability, quality...
The outbreak of the 2019 coronavirus disease (COVID-19) created an international public health emergency, challenging psychological resilience general population. Regarding this matter, a web-based survey was performed. Data were collected from following 1,668 self-selected volunteers: 800 athletes (28.30 ± 10.93 years old); 558 coaches (36.91 11.93 and 310 sports managers (42.07 13.38 old). To assess level stress, Impact Event Scale-Revised (IES-R) questionnaire used. results indicated that...
Most anticancer treatments act on oxidative-stress pathways by producing reactive oxygen species (ROS) to kill cancer cells, commonly resulting in consequential drug-induced systemic cytotoxicity. Physical activity (PA) has arisen as an integrative therapy, having positive health effects, including redox-homeostasis. Here, we investigated the impact of online supervised PA program promoter-specific DNA methylation, and corresponding gene expression/activity, 3 antioxidants- (SOD1, SOD2, CAT)...
Besides its substantial role in eye lens, αB-crystallin (HSPB5) retains fundamental function striated muscle during physiological or pathological modifications. In this study, we aimed to analyse the cellular and molecular factors driving functional response of HSPB5 protein different muscles from mice subjected an acute bout non-damaging endurance exercise C2C12 myocytes upon exposure pro-oxidant environment, chosen as “in vivo” vitro” models a stressing conditions, respectively. To end,...
The COVID-19 pandemic has posed several challenges for the oncology health care system. need to improve patients’ Quality of Life (QoL) through exercise, which is related survival and healing, increased, especially during lockdowns. Technologies are often used help with patient as well monitor exercise training. This case study, developed period, aims evaluate effectiveness a proposed home-based combined training (CT) regimen, supervised online lessons, in increasing QoL fatigue breast...
Regular physical activity can enhance immune function and effectively prevents the spread of cytokine response, thus reducing systemic low‐grade inflammation improving various markers. Moreover, regular exercise maintains redox homeostasis in skeletal muscle other tissues, including cells, but interconnection between anti‐inflammatory effects with status cells is still poorly understood. With aim to verify overall beneficial effect training on system, we have examined acute short‐term a...
Considering the role of redox homeostasis in exercise-induced signaling and adaptation, this study focuses on exercise training-related intercellular communication status mediated by circulating extracellular vesicles (EVs). 19 healthy young males were divided into trained (TG, 7) untrained (UG, 12) subjects based their VO2MAX. The UG further randomly distributed experimental (UGEX, N = control (UGCTRL, 5) groups. steady state plasma EVs TG UGEX have been characterized for total number size,...
Background: Women's health has received renewed attention in the last few years including rehabilitation options for women affected by breast cancer. Dancing often been regarded as one attractive option supporting women's well-being and health, but research with recovering from cancer is still its infancy. Health multi-site pilot study that aimed to evaluate a dance programme recovery across five European countries. Methods: A standardized 32 h protocol introduced range of Latin American...
Background: Chronic kidney disease (CKD) will become the fifth leading cause of death in world by 2040. It is fundamental to prevent and treat this pathology reduce its impact on national health costs. This trial’s aim evaluate effects induced a combination consumed functional foods (FFs) with adapted physical activity (APA) progression CKD-related comorbidities. Methods: The study lasted 12 weeks. We divided 40 CKD patients into four groups: mixed (FF + APA), APA, FF control group (usual...
This study compared the effects of high-resistance training (RT) programs, with or without curcumin supplementation, on variables commonly associated metabolic syndrome (MetS), including body composition, blood pressure, and parameters. Eighty-one older adults at risk MetS (BMI > 25 kg/m2, fat mass 32%, systolic pressure 130 mmHg in half participants) were randomly assigned to six groups, which comprised as follows: four experimental groups involving either accentuated eccentric maximal...
This pilot study aimed to assess the feasibility and preliminary effects of a supervised, home-based exercise program in patients recovering from laparoscopic colorectal cancer surgery. A total 23 were included, with 13 participating intervention 10 receiving standard postoperative care. The group (intervention group) followed two-month structured program, while control received no exercise. Feasibility was demonstrated by 98% adherence reported adverse events. At T1, showed significant...
Background Strength training plays a crucial role in promoting healthy ageing and music might affect how individuals perform perceive strength exercises. This study aimed to investigate the effects of self-selected (SSM) on muscle affective states during maximal isometric contractions customized leg extension. Methods Twenty-six middle-aged males (50.8 ± 8.4 years) performed endurance tests under three different conditions: SSM, motivational (MM), control condition (CC). Peak force Rate...
Breast cancer (BC) is one of the most commonly diagnosed types in women. Oxidative stress may contribute to etiology through several mechanisms. A large body evidence indicates that physical activity (PA) has positive effects on different aspects BC evolution, including mitigation negative induced by medical treatment. With aim verify capacity PA counteract treatment systemic redox homeostasis postsurgery female patients, we have examined modulation circulating levels oxidative and...
The international literature emphasizes the importance of physical activity (PA) in first steps after cancer surgery. regular practice exercise causes positive adaptations on several functional capacities, with consequences patients’ quality life. This project aims to evaluate effect a post-operative training protocol, structured by taking into account both cancer-related issues and presence comorbidities, capacities life breast survivors. Therefore, it was necessary create synergy between...