A5043519898- Genomics and Phylogenetic Studies
- Environmental DNA in Biodiversity Studies
- Identification and Quantification in Food
- Genetic diversity and population structure
- Plant biochemistry and biosynthesis
- Metabolomics and Mass Spectrometry Studies
- Traditional Chinese Medicine Analysis
- Chromatography in Natural Products
- Molecular Biology Techniques and Applications
- Plant and Fungal Species Descriptions
- Phytochemistry and Biological Activities
- Ginseng Biological Effects and Applications
- Plant Gene Expression Analysis
- Hemiptera Insect Studies
- Insect symbiosis and bacterial influences
- Natural product bioactivities and synthesis
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Microbial Community Ecology and Physiology
- Photosynthetic Processes and Mechanisms
- Microbial Natural Products and Biosynthesis
- Phytoplasmas and Hemiptera pathogens
- Pharmacological Effects of Natural Compounds
- Insect and Arachnid Ecology and Behavior
- Insect-Plant Interactions and Control
Tianjin University of Traditional Chinese Medicine
2016-2025
Qingdao Agricultural University
2025
Tsinghua University
2025
Tianjin haihe hospital
2022-2024
Thermal Power Research Institute
2024
Chongqing Three Gorges University
2022-2023
Xi'an International Studies University
2022
Beijing University of Technology
2022
Tianjin International Joint Academy of Biomedicine
2015-2020
Civil Aviation University of China
2019
Two offline multidimensional chromatography/high-resolution mass spectrometry systems (method 1: fractionation and online two-dimensional liquid chromatography, 2D-LC; method 2: 2D-LC) were established to characterize the metabolites simultaneously from three Glycyrrhiza species. Ion exchange chromatography in first-dimensional (1D) separation was well fractionated between acidic (mainly triterpenoids) weakly components (flavonoids). These obtained subsamples got sophisticated by second (2D)...
Neutrophil extracellular traps (NETs) are important pieces of equipment for neutrophils. Excess NETs play promoting roles in cancer-associated thrombosis (CAT). Therefore, directing formation is a promising therapeutic strategy and related diseases. Diosmetin, an antioxidant flavonoid derived from dietary sources, might be involved CAT. Firstly, the tests cell-free DNA Immunofluorescence were applied to evaluate levels Luminol-based chemiluminescence DCFH-DA probe used detect reactive oxygen...
Background . Coronary artery atherosclerosis is a chronic inflammatory disease. This study aimed to identify the key changes of gene expression between early and advanced carotid atherosclerotic plaque in human. Methods Gene dataset GSE28829 was downloaded from Expression Omnibus (GEO), including 16 13 stage samples human carotid. Differentially expressed genes (DEGs) were analyzed. Results 42,450 obtained dataset. Top 100 up- downregulated DEGs listed. Functional enrichment analysis Kyoto...
In this study, we sequenced the first full-length insect transcriptome using Erthesina fullo Thunberg based on PacBio platform. We constructed quantitative transcription map of animal mitochondrial genomes and built a straightforward concise methodology to investigate gene transcription, RNA processing, mRNA maturation several other related topics. Most results were consistent with previous studies, while best our knowledge some findings reported for time in study. The new included high...
Triple-negative breast cancer refers to that does not express estrogen receptor (ER), progesterone (PR), or human epidermal growth factor 2 (Her2). This study aimed identify the key pathways and genes find potential initiation progression mechanism of triple-negative (TNBC).We downloaded gene expression profiles GSE76275 from Gene Expression Omnibus (GEO) datasets. microarray Super-Series sets are composed data 265 samples which included 67 non-TNBC 198 TNBC. Next, all differentially...
Abstract High-throughput sequencing of chloroplast genomes has been used to gain insight into the evolutionary relationships plant species. In this study, we sequenced complete four species in Meconopsis genus: M . racemosa , integrifolia (Maxim.) Franch, horridula and punicea These plants grow wild are recognized as having important medicinal ornamental applications. The results showed that size genome ranges from 151864 153816 bp. A total 127 genes comprising 90 protein-coding genes, 37...
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain or discomfort. Previous studies have illustrated that the gut microbiota might play critical role in IBS, but conclusions of these studies, based on various methods, were almost impossible to compare, and reproducible microorganism signatures still question. To cope with this problem, previously published 16S rRNA gene sequencing data from 439 fecal samples, including 253 IBS samples 186...
Swertia mussotii is an important medicinal plant that has great economic and value found on the Qinghai Tibetan Plateau. The complete chloroplast (cp) genome of S. 153,431 bp in size, with a pair inverted repeat (IR) regions 25,761 each separate large single-copy (LSC) region 83,567 small (SSC) 18,342 bp. cp encodes 84 protein-coding genes, 37 transfer RNA (tRNA) eight ribosomal (rRNA) genes. identity, number, GC content genes were similar to those genomes other Gentianales species. Via...
Although single-targeting anti-platelet agents are used extensively in clinics, their limitations resistance and bleeding have started a trend of combination therapy. Danhong injection (DHI) is widely prescribed medicine for cardiovascular cerebrovascular diseases China. However, its precise clinical efficacy functional components remain unexplored. In this study, we investigated the anti-thrombotic role chemical basis DHI. photochemically-induced thrombosis model, DHI effectively dissolved...
Ampelopsis humulifolia (A. humulifolia) and japonica japonica), which belong to the family Vitaceae, are valuably used as medicinal plants. The chloroplast (cp) genomes have been recognized a convincing data for marker selection phylogenetic studies. Therefore, in this study we reported complete cp genome sequences of two species. Results showed that A. were 161,724 161,430 bp length, respectively, with 37.3% guanine-cytosine (GC) content. A total 114 unique genes identified each genome,...
This work was designed to evaluate the coverage of data-dependent acquisition (DDA) extensively utilized in untargeted metabolite/component identification food sciences and pharmaceutical analysis. Using saponins from flower buds Panax ginseng (PGF) as an example, precursor ions list (PIL)-including DDA on a Q-Orbitrap mass spectrometer could enable higher than other four MS2 approaches characterizing PGF ginsenosides. A "Virtual Library Ginsenoside" containing 13,536 ginsenoside molecules...
Pentatomomorpha is one of the most diversified infraorders true bugs (Insecta: Hemiptera: Heteroptera). The phylogenetic relationships among superfamilies within this infraorder are still in dispute. In study, 31 species representing 26 pentatomomorphan and four cimicomorphan putative families were chosen, six Hox gene fragments with as many 4 kilobases for each representative analyzed to reconstruct phylogeny Pentatomomorpha. (Homeotic) family a group nuclear genes, which considered...
Abstract Gleditsia sinensis is an endemic species widely distributed in China with high economic and medicinal value. To explore the genomic evolution phylogenetic relationships of G. , complete mitochondrial (mt) genome was sequenced assembled, which firstly reported . The mt circular 594,121 bp length, including 37 protein-coding genes (PCGs), 19 transfer RNA (tRNA) 3 ribosomal (rRNA) genes. overall base composition 27.4% for A, T, 22.6% G, 22.7% C. comparative analysis PCGs Fabaceae...
Radix
Characterization and spatial distribution studies of the metabolome in plants are crucial for revealing physiology developing functional foods. Using rhizome Glycyrrhiza uralensis as a case, we integrated desorption electrospray ionization-mass spectrometry imaging (DESI-MSI) high-resolution liquid chromatography/mass approaches aimed at characterizing locating both small molecules macromolecular polysaccharides. Under optimal conditions, 21 flavonoids 12 triterpenoids were detected...
Erigeron breviscapus has been widely used in traditional Chinese medicine (TCM) and its total flavonoid component is commonly to treat ischemic stroke, coronary heart disease, diabetes hypertension. Scutellarin the major ingredient of E. scutellarein one main bioactive metabolites scutellarin vivo, but latter's pharmacological activities have not fully characterized. Provided evidence that could inhibit platelet aggregation, effect on rat washed platelets underlying mechanisms were evaluated...
<title>Abstract</title> Following the end of zero-COVID policy, China’s economic recovery elicited high hopes but turned out to be disappointing in 2023. This paper provides a novel explanation for slow based on city network disruption and restructuring after major shocks. The supply-demand connections, once disrupted by lockdowns, could not revert their pre-lockdown state reopening. Instead, they underwent further restructuring, incurring considerable transaction costs. Using unique dataset...
Meloidogyne incognita is an economically important plant-parasitic nematode that can infect thousands of different plant species. During its interaction with host plants, M. synthesises numerous effectors in oesophageal glands, which are then secreted into tissues. Here, we characterised the effector MiISE23 and found it could suppress immune responses. In situ hybridisation showed was expressed subventral glands. Transgenic Arabidopsis plants expressing were more susceptible to incognita,...