A5002600613- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Nutrition and Health in Aging
- Gastric Cancer Management and Outcomes
- Traditional Chinese Medicine Studies
- Cancer, Lipids, and Metabolism
- Spinal Fractures and Fixation Techniques
- Acupuncture Treatment Research Studies
- Healthcare and Venom Research
- Vitamin D Research Studies
- Cancer Mechanisms and Therapy
- Infectious Diseases and Tuberculosis
- Lung Cancer Treatments and Mutations
- Lipid metabolism and disorders
- Medical Research and Treatments
- RNA modifications and cancer
- Traditional Chinese Medicine Analysis
- Pancreatitis Pathology and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cardiovascular Health and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Lung Cancer Research Studies
Sun Yat-sen University
2017-2025
Lishui City People's Hospital
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024-2025
Chongqing Medical University
2011-2025
The First Affiliated Hospital, Sun Yat-sen University
2025
First Affiliated Hospital of Anhui Medical University
2022-2024
Anhui Medical University
2022-2024
Eighth Affiliated Hospital of Sun Yat-sen University
2021-2024
Xinqiao Hospital
2024
Fudan University Shanghai Cancer Center
2020-2024
Abstract Brown adipose tissue (BAT) dissipates energy and its activity correlates with leanness in human adults. 18 F-fluorodeoxyglucose ( F-FDG) positron emission tomography coupled computer (PET/CT) is still the standard for measuring BAT activity, but exposes subjects to ionizing radiation. To study function large cohorts, novel diagnostic tools are needed. Here we show that brown adipocytes release exosomes activation increases exosome release. Profiling miRNAs released from adipocytes,...
The relationship between sarcopenia and insulin resistance (IR) has seldom been reported. Triglyceride-glucose (TyG) index, a new IR indicator, gained traction as prognostic tool for many diseases. We aimed to investigate whether the level of TyG index was related incidence sarcopenia.
Increased mammary epithelial expression of the human growth hormone (hGH) gene is associated with acquisition pathological proliferation. We report here that autocrine hGH production by carcinoma cells increased and transcriptional activity homeobox domain containing protein HOXA1. Forced HOXA1 in resulted total cell number primarily promotion survival mediated up-regulation Bcl-2. also abrogated apoptotic response to doxorubicin. cells, a Bcl-2-dependent manner, dramatic enhancement...
Abstract The present study aims to assess the treatment outcome of patients with diabetes and tuberculosis (TB-DM) at an early stage using machine learning (ML) based on electronic medical records (EMRs). A total 429 were included Chongqing Public Health Medical Center. random-forest-based Boruta algorithm was employed select essential variables, four models a fivefold cross-validation scheme used for modeling model evaluation. Furthermore, we adopted SHapley additive explanations interpret...
Purpose: To determine the toxicity profile of transarterial chemoembolization (TACE) at 6 months and 1 year after treatment in patients with hepatocellular carcinoma (HCC) a standardized oncology protocol so that TACE could be compared systemic chemotherapeutic regimens for liver cancer. Materials Methods: The study was authorized by institutional review board. Between January 2002 2007, 190 (155 men, 35 women; median age, 65 years; age range, 18–84 years) HCC who underwent were identified...
To identify the prognostic value and staging categories of masticator space involvement in nasopharyngeal carcinoma (NPC) as determined with anatomic criteria ("anatomic involvement") to determine whether it is necessary for described American Joint Committee on Cancer exclude medial lateral pterygoid muscles.This retrospective study was approved by institutional review board, requirement obtain informed consent waived. NPC diagnosed 924 patients magnetic resonance (MR) imaging, medical...
Abstract Background: Studies have shown that the combination of PD-1 inhibitors with chemotherapy exhibits promising efficacy as a first-line treatment for Asian patients recurrent or metastatic nasopharyngeal carcinoma (R/M NPC). This presentation reports results global phase 3 clinical trial ethnically diverse treated penpulimab plus vs. placebo therapy R/M NPC (NCT04974398). Methods: AK105-304 was conducted across 46 sites worldwide. Participants aged 18-75 years previously...
Reactive oxygen species (ROS) are considered a major factor contributing to sperm DNA damage during preparation for assisted reproductive technologies (ART). This study aimed investigate whether microfluidic sorting can select with low fragmentation index (DFI) and explore the underlying mechanisms. We compared effects of three methods-swim-up, density-gradient centrifugation, sorting-on quality integrity. Semen samples from 12 patients were divided into equal portions processed using...
Heavy metal exposure is acknowledged as a risk factor for poor health. However, the effect of heavy on prevalence gallstones still unknown. Therefore, we investigated relationship between concentrations and among US adults. Multivariate logistic regression indicated that only urinary cadmium was an independent gallstones. Compared to low urine group, high group had elevated increased gallstone formation. Furthermore, weighted quantile sum model showed mixtures were not associated with...
Background and Aims Preparative hepatic irradiation (HIR), together with mitotic stimulation of hepatocytes, permits extensive repopulation by transplanted hepatocytes in rats mice. However, whole liver HIR is associated radiation-induced disease (RILD), which limits its potential therapeutic application. In clinical experience, restricting to a fraction the reduces susceptibility RILD. Here we test hypothesis that selected lobes regional should be sufficient correct some inherited metabolic...
Background: Piperine is the primary pungent alkaloid isolated from fruit of black peppercorns. used frequently in dietary supplements and traditional medicines. The objective present study was to investigate effects piperine on testis development pubertal rat. Methods: (0 or 5 10 mg/kg) gavaged 35-day-old male Sprague-Dawley rats for 30 days. Serum levels testosterone (T), luteinizing hormone (LH), follicle-stimulating (FSH) were measured. adult Leydig cell population also analyzed 65 days...
Our aim is to investigate the prevalence, awareness, treatment, and control status of hypertension explore associated factors among Sichuan Tibetan population.A cross-sectional investigation was conducted in region from September 2013 March 2014. Three thousand two hundred forty persons were included study through a multi-stage stratified clustering sampling. Participants received questionnaires physical examination. Blood pressure (BP) recorded three times after 5 min rest with mean taken...
Abstract Background The medical consortium is an intensive and disease-specific association that integrates tertiary public hospitals examination centers in China. We aimed to evaluate the feasibility of for screening upper gastrointestinal (GI) cancers (MCSC) by magnetically controlled capsule gastroscopy (MCCG). Methods 6627 asymptomatic subjects underwent MCCG as part health check-ups MCSC between March November 2018. Relevant clinical data were collected analyzed. Results detected 32...