Chiara Simeoli

ORCID: 0000-0003-4275-337X
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About
Contact & Profiles
Research Areas
  • Pituitary Gland Disorders and Treatments
  • Adrenal Hormones and Disorders
  • Adrenal and Paraganglionic Tumors
  • Hormonal Regulation and Hypertension
  • Growth Hormone and Insulin-like Growth Factors
  • Sexual Differentiation and Disorders
  • Stress Responses and Cortisol
  • Hormonal and reproductive studies
  • Neuroendocrine Tumor Research Advances
  • Adipose Tissue and Metabolism
  • Circadian rhythm and melatonin
  • MicroRNA in disease regulation
  • Cancer, Hypoxia, and Metabolism
  • Long-Term Effects of COVID-19
  • Glycogen Storage Diseases and Myoclonus
  • Sexual function and dysfunction studies
  • Glioma Diagnosis and Treatment
  • Metabolism and Genetic Disorders
  • Ophthalmology and Eye Disorders
  • Diet and metabolism studies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Extracellular vesicles in disease
  • Neuroblastoma Research and Treatments
  • Advanced Breast Cancer Therapies
  • Electrolyte and hormonal disorders

University of Naples Federico II
2015-2024

Federico II University Hospital
2010-2021

Sapienza University of Rome
2021

University of Molise
2013

<b><i>Introduction:</i></b> Hyperprolactinemia has been implicated in the pathogenesis of obesity and glucose intolerance is reportedly associated with an impaired metabolic profile. The current study aimed at investigating effects 12- 60-month treatment cabergoline (CAB) on syndrome (MetS) patients prolactinomas. <b><i>Patients Methods:</i></b> 61 prolactinomas (13 men, 48 women, 41 microadenoma, 20 macroadenoma), aged 34.4 ± 10.3 years,...

10.1159/000357810 article EN Neuroendocrinology 2013-01-01

Diabetes mellitus (DM) is one of the most frequent complications Cushing's syndrome (CS). The aim this study was to define changes in insulin sensitivity and/or secretion relation glucose tolerance categories newly diagnosed CS patients.Cross-sectional on 140 patients with CS.A total 113 women (80 pituitary disease and 33 adrenal disease, aged 41.7±15.7 years) 27 men (19 eight 38.1±20.01 at diagnosis were divided according into normal (CS/NGT), impaired fasting (CS/prediabetes), diabetes...

10.1530/eje-13-0754 article EN European Journal of Endocrinology 2013-11-20

Objective Cabergoline (CAB) has been found to be associated with increased risk of cardiac valve regurgitation in Parkinson's disease, whereas several retrospective analyses failed detect a similar relation hyperprolactinemic patients. The current study aimed at investigating disease before and after 24 60 months continuous treatment CAB only patients hyperprolactinemia. Subjects methods Forty (11 men 29 women, aged 38.7±12.5 years) newly diagnosed hyperprolactinemia entered the study....

10.1530/eje-13-0231 article EN European Journal of Endocrinology 2013-07-04

Mitotane is used as a post-operative adjuvant treatment for patients with adrenocortical carcinoma. Monitoring of plasma mitotane concentrations recommended, but we do not know what impact target have on patient outcome. To answer this question, retrospectively analyzed records in the Lysosafe Online® database (HRA Pharma, France) who were treated ≥6 months and had ≥3 measurements levels during follow-ups at 11 tertiary centers Italy from 2005 to 2017. We identified 110 median 46 (IQR,...

10.3390/jcm8111850 article EN Journal of Clinical Medicine 2019-11-02

Abstract Context Appropriate management of adrenal insufficiency (AI) in pregnancy can be challenging due to the rarity disease and lack evidence-based recommendations guide glucocorticoid mineralocorticoid dosage adjustment. Objective Multicenter survey on current clinical approaches managing AI during pregnancy. Design Retrospective anonymized data collection from 19 international centers 2013 2019. Setting Patients 128 pregnancies 113 women with different causes AI: Addison (44%),...

10.1210/clinem/dgaa266 article EN The Journal of Clinical Endocrinology & Metabolism 2020-05-19

Registry data show that Cushing's syndrome (CS) and adrenal insufficiency (AI) increase mortality rates associated with infectious diseases. Little information is available on susceptibility to milder forms of infections, especially those not requiring hospitalization. This study aimed investigate diseases in patients glucocorticoid disorders through the development a specific tool.We developed administered InfeCtions pAtients endocRinOpathies (ICARO) questionnaire, addressing events over...

10.1530/eje-22-0454 article EN cc-by European Journal of Endocrinology 2022-09-14
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