A5014071855- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Mosquito-borne diseases and control
- Coccidia and coccidiosis research
- Vector-borne infectious diseases
- Insect symbiosis and bacterial influences
- Viral Infections and Vectors
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Vector-Borne Animal Diseases
- Studies on Chitinases and Chitosanases
- Zoonotic diseases and public health
- Cardiovascular Conditions and Treatments
- Nematode management and characterization studies
- Agricultural safety and regulations
- Bat Biology and Ecology Studies
- Mollusks and Parasites Studies
- Dermatological diseases and infestations
- Cardiac pacing and defibrillation studies
- Climate Change and Health Impacts
- SARS-CoV-2 and COVID-19 Research
- Leptospirosis research and findings
- Virology and Viral Diseases
Instituto de Recursos Naturales y Agrobiología de Salamanca
2017-2025
Consejo Superior de Investigaciones Científicas
2025
Czech Academy of Sciences
2023
Ollscoil na Gaillimhe – University of Galway
2022
Sechenov University
2019-2020
Instituto de Investigación Biomédica de Salamanca
2012-2017
Universidad de Salamanca
2009-2017
REVIEW article Front. Physiol., 12 June 2012Sec. Systems Biology Archive Volume 3 - 2012 | https://doi.org/10.3389/fphys.2012.00196
Angiostrongylus chabaudi (arrows) on the endothelium of right ventricle a wildcat in Northern Greece
Abstract Human fascioliasis is a worldwide, pathogenic food-borne trematodiasis. Impressive clinical pictures comprising puzzling polymorphisms, manifestation multifocality, disease evolution changes, sequelae and mortality, have been reported in patients presenting with neurological, meningeal, neuropsychic ocular disorders caused at distance by flukes infecting the liver. Proteomic mass spectrometry analyses of Fasciola hepatica excretome/secretome identified numerous, several new,...
We analyze through a climatic model the influence of regional warming on geographical spreading and potential risk infection human dirofilariosis in Russia, Ukraine, other post-Soviet states from 1981 to 2011 estimate situation by 2030. The correctly predicts spatiotemporal location 97.10% 2154 clinical cases reported area during studied period, identified retrospective review literature. There exists also significant correlation between annual predicted Dirofilaria generations calculated...
Background The trematode Fasciola hepatica is the most widespread causative agent of fasciolosis, a parasitic disease that mainly affects humans and ruminants worldwide. During F . infection, newly excysted juveniles (FhNEJ) emerge in duodenum mammalian host migrate towards their definitive location, intra-hepatic biliary ducts. Understanding how traverses intestinal wall migrates liver pivotal for development more successful strategies against fasciolosis. central enzyme fibrinolytic system...
Plasmin, the final product of fibrinolysis, is a broad-spectrum serine protease that degrades extracellular matrix (ECM) components, function exploited by multiple pathogens for dissemination purposes. The trematode Fasciola hepatica leading cause fasciolosis, major disease livestock and an emerging zoonosis in humans. Infection success depends on ability F. newly excysted juveniles (FhNEJ) to penetrate host intestinal wall, process remains incompletely understood. We have previously shown...
Vaccine approaches for controlling Fasciola hepatica present a promising avenue, particularly considering increasing resistance to anthelmintic treatments and concerns over chemical residues. Targeting vaccine candidates that are expressed secreted during the early infective stage of F. could offer an effective alternative. This approach aims inhibit invasion migration juvenile parasites, which have not yet fully developed their immune evasion mechanisms, thereby preventing parasite...
The migration of the trematode parasite Fasciola hepatica within its vertebrate host following infection by ingestion metacercariae represents a critical event in establishment and survival. early stages infection, during which F. crosses intestinal barrier advances to liver through peritoneum, initiate changes that drive development from free-living state on pasture an obligate blood-feeding parasite. Using vivo mouse model, this study explores proteomic as it migrates peritoneal cavity (24...
<title>Abstract</title> Background <italic>Fasciola hepatica</italic> is the most common etiologic agent of fasciolosis, a parasitic disease that affects millions ruminants worldwide and zoonotic human infection public health concern. Upon ingestion infective metacercariae, <italic>F. newly excysted juveniles (FhNEJ) emerge in duodenum cross intestinal wall to initiate migration route culminates with their establishment within hepatic bile ducts. The ability FhNEJ exploit broad-spectrum...
Dirofilaria immitis is the causal agent of canine and feline cardiopulmonary dirofilariasis. Moreover, existence dirofilariasis implies a risk for human populations living in an endemic area which, parasite can cause pulmonary The Spanish epidemiological situation not well understood, lacking data from many central Northern provinces. In our study, on La Rioja (Northern Spain) have been obtained first time. overall prevalence D. dogs was 12% (9% patent 3% occult infections), being 11.6%...
Heartworm infection (Dirofilaria immitis) can cause kidney damage due to the presence of circulating microfilariae (mf) that contribute production and deposit immune complexes. It has been shown mf are a major source Wolbachia antigen during active infection. Here authors compared urine samples from 19 naturally infected dogs with (mf+) 12 without (mf−) for proteinuria anti-Wolbachia Surface Protein (-WSP) IgG in ELISA. Kidneys 6 mf+ 3 mf− were also examined by anti-WSP...