A5034742358- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Retinal and Optic Conditions
- Nuclear physics research studies
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Nuclear Physics and Applications
- Retinal and Macular Surgery
- Atomic and Molecular Physics
- X-ray Spectroscopy and Fluorescence Analysis
- Forest ecology and management
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Astronomical and nuclear sciences
- Advanced NMR Techniques and Applications
- Retinopathy of Prematurity Studies
- Ophthalmology and Visual Impairment Studies
- Ocular Diseases and Behçet’s Syndrome
- Photoreceptor and optogenetics research
- melanin and skin pigmentation
- Heavy metals in environment
- Ocular Surface and Contact Lens
- Quantum Chromodynamics and Particle Interactions
- Angiogenesis and VEGF in Cancer
- Nasolacrimal Duct Obstruction Treatments
Japanese Red Cross Society Wakayama Medical Center
2008-2025
Kyoto University
2010-2019
Topcon (Netherlands)
2016
Kyoto City Hospital
2011
Doshisha University
2011
University of Shiga Prefecture
1999-2003
Ehime University
1992-1998
Showa General Hospital
1993
Yamaguchi University
1988
Cancer Institute (WIA)
1988
Purpose.: Retinitis pigmentosa (RP), a major cause of blindness in developed countries, has multiple causative genes; its prevalence differs by ethnicity. Usher syndrome is the most common form syndromic RP and accompanied hearing impairment. Although molecular diagnosis challenging, recent technological advances such as targeted high-throughput resequencing are efficient screening tools. Methods.: We performed comprehensive testing 329 Japanese patients using custom capture panel that...
To evaluate the hyperreflective foci in branch retinal vein occlusion and central depicted by spectral-domain optical coherence tomography (OCT).Consecutive series of 73 eyes patients with (58 15 occlusion) who had Spectralis OCT images obtained were retrospectively reviewed, comparing color fundus photographs fluorescein angiography.Hyperreflective detected 54 (74.0%) OCT, hard exudates 17 (23.3%) photography. Hard on corresponded to confluence mainly around outer plexiform layer unaffected...
Purpose.: Although stromal cell-derived factor (SDF)-1 contributes to angiogenesis, its effects on sprouting angiogenesis remain ill defined. The authors investigated how SDF-1 and receptor, CXCR4, influence neovascular sprouting. Methods.: In vivo retinal vascular development was evaluated ex induced by endothelial growth (VEGF). Time-sequential observation followed the quantification of movements in sprouts microglia. Real-time PCR performed for measurement mRNA levels. Results.:...
Purpose To assess macular photoreceptor abnormalities in eyes with retinitis pigmentosa (RP) preserved central vision using adaptive optics scanning laser ophthalmoscopy (AO-SLO). Methods Fourteen of 14 patients RP (best-corrected visual acuity 20/20 or better) and 12 volunteers underwent a full ophthalmologic examination, fundus autofluorescence, spectral-domain optical coherence tomography (SD-OCT), imaging prototype AO-SLO system. Cone density spatial organization the cone mosaic were...
To investigate the papillofoveal distance and its association with retinal thickness on optical coherence tomography (OCT) images after vitrectomy for diabetic macular edema (DME).In this retrospective case series, 72 eyes of 57 consecutive patients who underwent DME were included. Retinal dissecting fovea horizontally obtained using OCT before vitrectomy. After identification disc margin presumed foveal center, was measured images. The peeling inner limiting membrane (ILM) evaluated.The...
In Brief Purpose: To investigate the prevalence and spatial distribution of cystoid spaces (CS) in retinitis pigmentosa patients with spectral domain optical coherence tomography. Methods: A total 529 eyes 275 were examined The presence or absence CS was judged for each eye. Retinal layer outer retinal status where existed also investigated. Statistical analysis performed using 1 eye per patient. Results: Cystoid present 119 (22.5%) 74 (26.9%). There no significant differences between cases...
Ophthalmologists sometimes face difficulties in identifying the origin of visual acuity (VA) loss a retinitis pigmentosa (RP) patient, particularly before cataract surgery: or retinal disease state. Therefore, it is important to identify significant factors correlating with VA. Nowadays, blood flow superficial and deep layers can be estimated non-invasively using optical coherence tomography angiography (OCTA). We per layer by OCTA; investigated correlation between VA other parameters...
Purpose.: To evaluate the clinical utility of wide-field fundus autofluorescence (FAF) in patients with cone dystrophy and cone-rod dystrophy.
Purpose: To study changes in choroidal thickness with ranibizumab treatment for neovascularization (CNV). Design: Prospective case series. Methods: This prospective consisted of 60 CNV-affected eyes patients treated intravitreal injections using an on-demand protocol after initial loading phase. The studied included 20 age-related macular degeneration (AMD), polypoidal vasculopathy (PCV), and myopic CNV. In the AMD PCV, at fovea was measured optical coherence tomography enhanced depth...
Bietti crystalline retinopathy (BCR) is a distinct retinal degenerative disease characterised by degeneration with many yellow-white crystals located mainly at the posterior pole area. Using spectral domain-optical coherence tomography (SD-OCT), structural change in retina was investigated.Patients diagnosed BCR (n=12), retinitis pigmentosa (RP, n=292) and cone dystrophy (n=16) were included this study. The authors examined fundus photographs SD-OCT, infrared autofluorescence images of these...
To report the clinical and immunological characterization of paraneoplastic retinopathy (PR) to investigate association between spectral-domain optical coherence tomography (SDOCT) findings targets autoantibodies in PR.We retrospectively enrolled eight patients (age range, 57-85 years; four men women) suspected having PR. All underwent comprehensive ophthalmic examinations, including best-corrected visual acuity (BCVA) measurement, slitlamp kinetic field testing with Goldmann perimetry,...
To determine the prevalence and annual trend of number incident cases myopia high in children. A nationwide, comprehensive claims database study. Of 15 million children aged ≤14 years, those covered by universal health insurance were included. The validation study claims-based definitions was conducted using 14 654 individuals years recruited from 11 diverse medical facilities. This comprises a national analysis multicenter Data National Database Health Insurance Claims Specific Checkups...
Measurements of angular distributions the cross sections and analyzing powers for elastic inelastic scatterings 65 MeV polarized protons from $^{12}\mathrm{C}$, $^{24}\mathrm{Mg}$, $^{28}\mathrm{Si}$, $^{32}\mathrm{S}$ are reported. Coupled channels analyses scattering data presented assuming ${0}_{1}^{+}$, ${2}_{1}^{+}$, ${4}_{1}^{+}$ states to be members ground band, ${0}_{2}^{+}$ state begin the\ensuremath{\beta} ${3}_{1}^{\mathrm{\ensuremath{-}}}$...
Although the cause of multiple evanescent white dot syndrome (MEWDS) has not been elucidated, 2 reports have described cases MEWDS after vaccination. A 16-year-old girl presented with throat pain, headache, and photopsia in left eye weeks receiving a human papillomavirus (HPV) The clinical examination revealed numerous dots on fundus, visual field loss, abnormal electroretinography results, which are concordant diagnosis MEWDS. fundus disappeared within few months, her continued to...