Alan Brnabic

ORCID: 0000-0003-4303-2515
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About
Contact & Profiles
Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • Psoriasis: Treatment and Pathogenesis
  • Bipolar Disorder and Treatment
  • Dermatology and Skin Diseases
  • Lung Cancer Treatments and Mutations
  • Musculoskeletal pain and rehabilitation
  • Treatment of Major Depression
  • Schizophrenia research and treatment
  • Statistical Methods in Clinical Trials
  • Lung Cancer Diagnosis and Treatment
  • Diabetes Management and Research
  • Hip and Femur Fractures
  • Bone health and osteoporosis research
  • Advanced Causal Inference Techniques
  • Diabetes Treatment and Management
  • Nail Diseases and Treatments
  • Pharmaceutical studies and practices
  • Mental Health Research Topics
  • Lung Cancer Research Studies
  • Therapeutic Uses of Natural Elements
  • Asthma and respiratory diseases
  • Chronic Disease Management Strategies
  • Dementia and Cognitive Impairment Research
  • Mental Health Treatment and Access
  • Psychosomatic Disorders and Their Treatments

Eli Lilly (United States)
2015-2025

Hudson Institute
2022

IP Australia
2022

Oregon Medical Research Center
2020

Australian Broadcasting Corporation (Australia)
2008-2016

Prince of Wales Hospital
2005

The University of Sydney
2000-2003

UNSW Sydney
2003

Neuroscience Research Australia
2003

Hornsby Ku-ring-gai Hospital
1999-2001

This study reports chronic pain prevalence in a randomly selected sample of the adult Australian population. Data were collected by Computer-Assisted Telephone Interview (CATI) using generated telephone numbers and two-stage stratified design. Chronic was defined as experienced every day for three months six prior to interview. There 17,543 completed interviews (response rate=70.8%). reported 17.1% males 20.0% females. For males, peaked at 27.0% 65--69 year age group females, 31.0% oldest...

10.1016/s0304-3959(00)00355-9 article EN Pain 2001-01-01

Little is known about the relationship between chronic pain status and overall use of healthcare. We examined whether disabling was associated with more frequent healthcare in three settings: primary care, emergency departments, hospital admissions. used data from Computer-Assisted Telephone Interviews (CATI) 17,543 residents New South Wales, Australia aged 16 over who were randomly sampled using a population-based two-stage stratified sample random digit dialling methods. The response rate...

10.1016/j.pain.2004.05.020 article EN Pain 2004-07-30

Berk M, Brnabic A, Dodd S, Kelin K, Tohen Malhi GS, L, Conus P, McGorry PD. Does stage of illness impact treatment response in bipolar disorder? Empirical data and their implication for the staging model early intervention.Bipolar Disord 2011: 13: 87–98. © 2011 The Authors.Journal compilation John Wiley & Sons A/S. Objective: suggests that stages disorder respond better to treatments have a more favourable prognosis. This study aims provide empirical support model, allied construct...

10.1111/j.1399-5618.2011.00889.x article EN Bipolar Disorders 2011-02-01

This study compared an outpatient pain self-management (PSM) program, using cognitive-behavioural therapy and exercises, with 2 control conditions in 141 chronic patients aged > 65 years. Results immediately posttreatment indicated that relative to the Exercise-Attention Control (EAC) group, PSM group was significantly improved on measures of distress, disability, mood, unhelpful beliefs, functional reach. The mean effect size for these gains 0.52 (range: 0.44-0.68). By 1-month follow-up,...

10.1016/j.pain.2013.02.009 article EN Pain 2013-02-26

Standard network meta-analysis (NMA) and indirect comparisons combine aggregate data from multiple studies on treatments of interest, assuming that any effect modifiers are balanced across populations. Population adjustment methods relax this assumption using individual patient one or more studies. However, current matching-adjusted comparison simulated treatment limited to pairwise cannot predict into a specified target population. Existing meta-regression approaches incur aggregation bias....

10.1111/rssa.12579 article EN cc-by Journal of the Royal Statistical Society Series A (Statistics in Society) 2020-06-01

To determine fall risk factors in nursing home and intermediate-care residents who can cannot stand unaided.Prospective cohort study.Residential elderly care facilities Sydney, Australia.One thousand people aged 65 to 103 (mean age +/- standard deviation: 85.0 7.4).Accidental falls.Fall rates were highest those with fair standing balance, intermediate the best lowest worst balance. This nonlinear pattern was even more striking when subjects categorized according their balance ability rise...

10.1046/j.1532-5415.2003.51518.x article EN Journal of the American Geriatrics Society 2003-10-24

Abstract Background Behavioural exposure methods can reduce pain‐avoidance behaviours, but outcomes vary. One possible explanation is that patients employ cognitive (experiential) avoidance during behavioural exposure. If so, reducing should help. option interoceptive ( IE ), which involves sustained (via attention) to pain sensations. In order test if could improve from exposure, this study with mixed chronic compared a therapy CBT ) management programme incorporating either or distraction...

10.1002/j.1532-2149.2013.00383.x article EN European Journal of Pain 2013-08-13

Rapid improvement of psoriasis is valued by patients and should be considered to an important factor in treatment selection. We investigated Psoriasis Area Severity Index (PASI) Dermatology Life Quality (DLQI) response rates within the first 12 weeks compare rapid 11 biologic therapies for moderate-to-severe using Bayesian Frequentist network meta-analyses (NMA). A systematic literature review was conducted identify phase 3, double-blind, randomized, controlled trials adult with treated...

10.1007/s13555-019-00337-y article EN cc-by-nc Dermatology and Therapy 2019-11-04

This study compares the outcomes, from pretreatment to 1-year follow-up, of an outpatient, CBT-based pain self-management program (PSM) that included exercises, education, and coping strategies, with a control condition (exercise-attention control, EAC) exercises for attention treatment team. We previously reported short-term results (to 1-month follow-up) same study. new paper considers important issue maintenance treatment-related gains. The participants (n = 141) were heterogeneous sample...

10.1097/j.pain.0000000000000729 article EN Pain 2016-09-24

Abstract Background Clinical trials study treatment outcomes under stringent conditions, capturing incompletely the heterogeneity of patient populations and complexities encountered in real‐world practice. Objectives To compare effectiveness anti‐interleukin (IL)‐17A biologics relative to other approved patients with moderate‐to‐severe psoriasis. Methods The Psoriasis Study Health Outcomes (PSoHO) is an ongoing 3‐year observational cohort adults chronic plaque psoriasis initiating or...

10.1111/jdv.18376 article EN cc-by-nc-nd Journal of the European Academy of Dermatology and Venereology 2022-06-29

Objectives To determine the prevalence and determinants of disability among elderly people living in community. Design A cross-sectional postal questionnaire survey. Setting Northern Sydney Area Health Service. Participants 1527 residents (622 men 905 women) aged 65 years over. Main outcome measures Self-reported chronic illnesses, injuries or conditions; difficulties with activities daily assessed by Assessment Questionnaire (HAQ); home modification use functional aids. Results "Arthritis...

10.5694/j.1326-5377.1998.tb139023.x article EN The Medical Journal of Australia 1998-05-01

Respiratory diseases represent a significant impact on health care. A cross-sectional, multicountry (India, Korea, Malaysia, Singapore, Taiwan, and Thailand) observational study was conducted to investigate the proportion of adult patients who received care for primary diagnosis asthma, allergic rhinitis (AR), chronic obstructive pulmonary disease (COPD), or rhinosinusitis.To determine AR, COPD, rhinosinusitis, frequency main symptoms reported.Patients ages ≥18 years, presented physician...

10.2500/aap.2016.37.3925 article EN Allergy and Asthma Proceedings 2016-01-22

To assess the cost-effectiveness of sensor-augmented insulin pump therapy with "Low Glucose Suspend" (LGS) functionality versus standard self-monitoring blood glucose in patients type 1 diabetes who have impaired awareness hypoglycemia.A clinical trial-based economic evaluation was performed which net costs and effectiveness two treatment modalities were calculated expressed as an incremental ratio (ICER). The outcome interest for rate severe hypoglycemia each arm LGS study. Quality-of-life...

10.1016/j.jval.2014.05.008 article EN cc-by-nc-nd Value in Health 2014-07-01
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