A5018682132- Advanced Sensor and Energy Harvesting Materials
- Diverse Aspects of Tourism Research
- Cruise Tourism Development and Management
- Tactile and Sensory Interactions
- Corporate Finance and Governance
- Dielectric materials and actuators
- Conducting polymers and applications
- Tourism, Volunteerism, and Development
- Hospitality and Tourism Education
- Non-Invasive Vital Sign Monitoring
- Wireless Body Area Networks
- Auditing, Earnings Management, Governance
- Polymer composites and self-healing
- Autophagy in Disease and Therapy
- Anodic Oxide Films and Nanostructures
- Wine Industry and Tourism
- Advanced MRI Techniques and Applications
- Neonatal Respiratory Health Research
- Lanthanide and Transition Metal Complexes
- Fluid Dynamics and Turbulent Flows
- Personal Information Management and User Behavior
- MicroRNA in disease regulation
- Recreation, Leisure, Wilderness Management
- Migration, Aging, and Tourism Studies
- Surface Modification and Superhydrophobicity
Northwestern University
2019-2025
Chan Zuckerberg Initiative (United States)
2024-2025
Chan Zuckerberg Biohub Chicago
2024-2025
Auckland University of Technology
2014-2024
Kennedy Krieger Institute
2023-2024
The University of Sydney
2016-2024
Lafayette College
2023
UCLA Medical Center
2019-2022
University of Chicago
2014-2022
Simpson University
2020-2021
Abstract Bioresorbable electronic stimulators are of rapidly growing interest as unusual therapeutic platforms, i.e., bioelectronic medicines, for treating disease states, accelerating wound healing processes and eliminating infections. Here, we present advanced materials that support operation in these systems over clinically relevant timeframes, ultimately bioresorbing harmlessly to benign products without residues, eliminate the need surgical extraction. Our findings overcome key...
Temporary postoperative cardiac pacing requires devices with percutaneous leads and external wired power control systems. This hardware introduces risks for infection, limitations on patient mobility, requirements surgical extraction procedures. Bioresorbable pacemakers mitigate some of these disadvantages, but they demand pairing external, systems secondary mechanisms control. We present a transient closed-loop system that combines time-synchronized, wireless network skin-integrated an...
Implantable devices capable of targeted and reversible blocking peripheral nerve activity may provide alternatives to opioids for treating pain. Local cooling represents an attractive means on-demand elimination pain signals, but traditional technologies are limited by rigid, bulky form factors; imprecise cooling; requirements extraction surgeries. Here, we introduce soft, bioresorbable, microfluidic that enable delivery focused, minimally invasive power at arbitrary depths in living tissues...
Precise form-fitting of prosthetic sockets is important for the comfort and well-being persons with limb amputations. Capabilities continuous monitoring pressure temperature at skin-prosthesis interface can be valuable in fitting process development dangerous regions increased as volume changes during daily activities. Conventional transducers sensors cannot provide comfortable, irritation-free measurements because their relatively rigid construction requirements wired interfaces to external...
Abstract Boards are crucial to shareholder wealth. Yet little is known about how oversight affects director incentives. Using exogenous shocks institutional investor portfolios, we find that distraction weakens board oversight. Distracted institutions less likely discipline ineffective directors with negative votes. Consequently, independent face weaker monitoring incentives and exhibit poor performance; also more frequently appointed. Moreover, the adverse effects of on various corporate...
Recently introduced classes of thin, soft, skin-mounted microfluidic systems offer powerful capabilities for continuous, real-time monitoring total sweat loss, rate and biomarkers. Although these technologies operate without the cost, complexity, size, weight associated with active components or power sources, rehydration events can render previous measurements irrelevant detection anomalous physiological events, such as high requires user engagement to observe colorimetric responses. Here...
Vital signs monitoring is a fundamental component of ensuring the health and safety women newborns during pregnancy, labor, childbirth. This often first step in early detection pregnancy abnormalities, providing an opportunity for prompt, effective intervention to prevent maternal neonatal morbidity mortality. Contemporary systems require numerous devices wired large base units; at least five separate with distinct user interfaces are commonly used detect uterine contractility, blood...
Abstract Continuous monitoring of vital signs is an essential aspect operations in neonatal and pediatric intensive care units (NICUs PICUs), particular importance to extremely premature and/or critically ill patients. Current approaches require multiple sensors taped the skin connected via hard‐wired interfaces external data acquisition electronics. The adhesives can cause iatrogenic injuries fragile, underdeveloped skin, wires complicate even most routine tasks patient care. Here,...
Abstract Indwelling arterial lines, the clinical gold standard for continuous blood pressure (BP) monitoring in pediatric intensive care unit (PICU), have significant drawbacks due to their invasive nature, ischemic risk, and impediment natural body movement. A noninvasive, wireless, accurate alternative would greatly improve quality of patient care. Recently introduced classes skin‐interfaced devices offer capabilities continuous, precise physiologic waveforms vital signs neonatal patients,...
Abstract Many recently developed classes of wireless, skin‐interfaced bioelectronic devices rely on conventional thermoset silicone elastomer materials, such as poly(dimethylsiloxane) (PDMS), soft encapsulating structures around collections electronic components, radio frequency antennas and, commonly, rechargeable batteries. In optimized layouts and device designs, these materials provide attractive features, most prominently in their gentle, noninvasive interfaces to the skin even at...
Human bladder cancer (BC) is the fourth most common in United States. Investigation of strategies aiming to elucidate tumor growth and metastatic pathways BC critical for management this disease. Here we found that ATG7 expression was remarkably elevated human urothelial carcinoma N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)-induced mouse invasive BC. Knockdown resulted a significant inhibitory effect on tumorigenic cells both vitro vivo by promoting p27 inducing cell cycle arrest at G2/M...
The ability to characterize bulk and interfacial transport properties of polymer electrolytes is critical realizing their potential applications in electrochemical energy storage devices. In this study, we leverage custom microfabricated interdigitated electrode array (IDEs) as a platform probe ion films through impedance spectroscopy (EIS) measurements. Using poly(ethylene oxide) (PEO) blended with lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) model dry electrolyte system, investigate...
Abstract Purpose To develop a 3D, high‐sensitivity CEST mapping technique based on the 3D stack‐of‐spirals (SOS) gradient echo readout, proposed approach was compared with conventional acquisition techniques and evaluated for its efficacy in concurrently of guanidino (Guan) amide human brain at 3 T, leveraging polynomial Lorentzian line‐shape fitting (PLOF) method. Methods Saturation time recovery delay were optimized to achieve maximum efficiency. The 3DSOS method segmented EPI (3DEPI),...
The X-linked inhibitor of apoptosis protein (XIAP) is a well-known potent suppressor and also participates in cancer cell biological behaviors, therefore attracting great attentions as potential antineoplastic therapeutic target for past years. Anti-IAP therapy reported to be closely related epidermal growth factor receptor (EGFR) expression level. However, whether how XIAP modulates EGFR remains largely unknown. Human was knockdown with short-hairpin RNA two different bladder lines, T24T...
Abstract Robust literature supports the positive effects of kangaroo mother care (KMC) on infant physiologic stability and parent–infant bonding in Neonatal Intensive Care Unit (NICU). Comparatively little is known about father (KFC) NICU, KFC implementation has been limited. Our pilot feasibility study objective was to examine premature infants fathers as compared KMC. Parents preterm NICU independently completed a 90‐min Kangaroo (KC) session consecutive days. Infant heart rate variability...
Continuous kinematic biofeedback during exercise interventions can lead to improved therapeutic outcomes in hand and wrist rehabilitation. Conventional methods for measuring joint kinematics typically allow only static measurements performed by specially trained therapists. This paper introduces skin-conformal, wearable wireless systems designed continuously accurately capture the angles of target joints, specifically wrist. Supported a computer vision-based calibration protocol run on smart...
Important insights into human health can be obtained through the non-invasive collection and detailed analysis of sweat, a biofluid that contains wide range essential biomarkers. Skin-interfaced microfluidic platforms, characterized by soft materials thin geometries, offer capabilities for in situ capture, storage, sweat its constituents. In ambulatory uses cases, ability to provide real-time feedback on loss, rate content, without visual inspection device, important. This paper introduces...
Using a novel dataset of firm product introductions, we examine whether public short campaigns (PSCs) have real impacts on targets. Targets introduce fewer new products and experience declines in productivity quality relative to matched firms following PSCs. These outcomes are partly attributed the withdrawal support from key stakeholders, resulting reduced access external capital, decreased employee commitment, weakened customer relationships. Our results suggest that nature PSCs has...