A5100427438- Nutrition and Health in Aging
- Diet and metabolism studies
- Pancreatic function and diabetes
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Dysphagia Assessment and Management
- Renal and related cancers
- Reproductive System and Pregnancy
- Reproductive Physiology in Livestock
- Liver Disease Diagnosis and Treatment
- Neuropeptides and Animal Physiology
- Intracerebral and Subarachnoid Hemorrhage Research
- Sympathectomy and Hyperhidrosis Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Galectins and Cancer Biology
- Chronic Kidney Disease and Diabetes
- Kruppel-like factors research
- Migraine and Headache Studies
- Injury Epidemiology and Prevention
- Systemic Sclerosis and Related Diseases
- Sodium Intake and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Neurogenesis and neuroplasticity mechanisms
- Chronic Disease Management Strategies
- Ginseng Biological Effects and Applications
Beijing Institute of Technology
2025
Nanjing Medical University
2021-2024
Jiangsu Province Hospital
2024
Wenzhou Medical University
2023-2024
First Affiliated Hospital of Wenzhou Medical University
2023-2024
Guizhou University
2024
Southwest Medical University
2010-2023
Beijing University of Chemical Technology
2023
National Center for Chronic and Noncommunicable Disease Control and Prevention
2023
Affiliated Hospital of Southwest Medical University
2022
Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stroma which can provide a potential therapy for diabetes mellitus. But the mechanism is still controversial. Also, status of BM-MSCs under hyperglycemia not known. In present study, we investigated in experimental-diabetic rat and demonstrated rescue experimental by diabetic MSCs transplantation.BM-MSCs were cultured multiple-differentiation was identified through induction into osteoblasts. passage 3 used following...
Objective: Inflammation, oxidative stress and decreased glucagon-like peptide-1 (GLP-1) are risk factors for cognitive impairment. Dipeptidyl peptidase-4 (DPP4) was identified as a novel adipokine capable of enhancing these factors. Hence, we investigated the relationship between plasma DPP4 activity impaired function in elderly Chinese population with normal glucose tolerance. Methods: We performed cross-sectional study using data from 1229 participants (60 years or older) Guilin. Plasma...
Excessive salt intake is a widespread health issue observed in almost every country around the world. A high diet (HSD) has strong correlation with numerous diseases, including hypertension, chronic kidney disease, and autoimmune disorders. However, mechanisms underlying HSD-promotion of inflammation exacerbation these diseases are not fully understood. In this study, we that HSD consumption reduced abundance gut microbial metabolite L-fucose, leading to more substantial inflammatory...
Background To enhance reproducibility and transparency, the International Committee of Medical Journal Editors (ICMJE) required that all trial reports submitted after July 2018 must include a data sharing statement (DSS). Accordingly, emerging biomedical journals authors to DSS in submissions for publication if were accepted. Nevertheless, it was unclear whether endocrinology metabolism had this request clinical reports. Therefore, we aimed explore requested submissions, their compliance...
Background: Malnutrition and comorbidity are two common geriatric syndromes. The pathology of pneumonia is multifactorial, making its diagnosis management a great challenge. Hospital-acquired (HAP) community-acquired (CAP) main types pneumonia. However, the effect syndromes on prognosis have not been clearly explored. Methods: We collected relevant electronic data inpatients aged over 65 years diagnosed with in Geriatrics Department Building First Affiliated Hospital Nanjing Medical...
Objective: To detect the combination protective effect of bone marrow mesenchymal stem cells (BMSCs) and Klotho gene on renal ischemia-reperfusion injury (RIRI).Methods: BMSCs isolated from rats were transfected with to form BMSCKl. We injected BMSCKl allogenic rat RIRI model. After 24 h 72 h, we detected serum creatinine (SCr), malondialdehyde (MDA), superoxide dismutase (SOD) in tissue, Hematoxylin-eosin (HE) staining, TUNEL pathology. The expression FoxO1 p-FoxO1 post-hypoxia tubular...
Abstract Due to their potential beneficial effects, anthocyanins and proanthocyanins have attracted great concern worldwide. Recently, anthocyanin/proanthocyanin‐related health products occupied a certain proportion of the market. However, there has not been systematical assessment on collecting analyzing relevant information. In this study, information sale four major online shopping platforms in China collected from November 2020 February 2021. A total 144 valid samples 91 brands were...
Sarcopenia has a remarkable negative impact on patients with liver diseases. We aimed to evaluate the of preoperative sarcopenia short-term outcomes after hepatectomy in benign A total 558 diseases undergoing were prospectively reviewed. Both muscle mass and strength measured define sarcopenia. Postoperative including complications, major complications comprehensive complication index (CCI) compared among four subgroups classified by strength. Predictors high CCI identified univariate...
Ketogenic diet (KD) has been proven to be an optional avenue in weight control. However, the impacts of KD on muscle strength and exercise endurance remain unclear. In this study, mice were randomly allocated normal groups assess their tolerance transcriptomic changes gastrocnemius. suppressed body-weight glucose levels augmented blood ketone mice. The total cholesterol, free fatty acids, β-hydroxybutyric acid higher triglycerides aspartate aminotransferase lower group. There was no notable...
Objective: Since decreased brain-derived neurotrophic factor (BDNF) and increased dipeptidyl peptidase-4 (DPP4) activity have both been implicated in the pathogenesis of mild cognitive impairment (MCI), aim our study was to evaluate association MCI with plasma DPP4 BDNF ratio (DBR) an elderly population normal glucose tolerance. Methods: We cross-sectionally measured C-reactive protein, interleukin-6, nitrotyrosine, 8-iso-PGF2a, calculated DBR a total 1,066 participants China. determined by...
Epithelial-Mesenchymal transition (EMT) is one of the origins myofibroblasts in renal interstitial fibrosis. Mesenchymal stem cells (MSCs) alleviating EMT has been proved, but concrete mechanism unclear. To explore mechanism, serum-free MSCs conditioned medium (SF-MSCs-CM) was used to treat rat tubular epithelial (NRK-52E) fibrosis induced by transforming growth factor-β1 (TGF-β1) which ameliorated EMT.Galectin-3 knockdown (Gal-3 KD) and overexpression OE) lentiviral vectors were established...
Abstract Background: In this study, we will assess the efficacy and safety of metoclopramide for treatment acute migraine (AM). Methods: We comprehensively search Cochrane Library, PUMBED, EMBASE, Google Scholar, Web Science, Allied Complementary Medicine Database, Chinese Biomedical Literature China National Knowledge Infrastructure from inception to July 1, 2019 identify any eligible studies. Only randomized controlled trials be considered inclusion. The study selection, data collection,...
To investigate the effects of human bone marrow mesenchymal stem cells/vascular endothelial growth factor (hBMSCs/VEGF) transplantation on early brain edema in rats with cerebral hemorrhage.Cultured hBMSCs vitro, transducted cells VEGF recombinant lentivirus vector to abtain hBMSCs/VEGF cells. Intracerebral hemorrhage (ICH) rat model was established by injection type Ⅰ collagenase and heparin into caudate putamen. 2 h after operation, were evaluated modified nerve function defect (mNSS)...
To investigate the impacts of ferulic acid (FA) on jumonji C domain-containing protein 6 (JMJD6) and synaptophysin in tissues hippocampus neonatal juvenile rats with intrauterine hypoxia-induced cognitive impairment. The Sprague-Dawley pregnant were randomly divided into three groups: control, hypoxia, hypoxia + FA. On day 14 pregnancy, model was created by placing hypoxic low-pressure experimental chamber for 2 hr a 3 days. In FA group, injected intraperitoneally 4% FA, once 7 group treated...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)