A5101862187- Folate and B Vitamins Research
- Pregnancy and preeclampsia studies
- Iron Metabolism and Disorders
- Gestational Diabetes Research and Management
- Head and Neck Surgical Oncology
- Nutritional Studies and Diet
- Hemoglobinopathies and Related Disorders
- Birth, Development, and Health
- Liver Disease Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Head and Neck Cancer Studies
- Fluoride Effects and Removal
- Hematopoietic Stem Cell Transplantation
- Child Nutrition and Water Access
- Nutrition and Health in Aging
- Natural product bioactivities and synthesis
- Esophageal and GI Pathology
- Wound Healing and Treatments
- Meningioma and schwannoma management
- Global Maternal and Child Health
- Analytical Chemistry and Chromatography
- Sinusitis and nasal conditions
- Chromatography in Natural Products
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
National Center on Birth Defects and Developmental Disabilities
2015-2025
Centers for Disease Control and Prevention
2014-2025
National Heart Lung and Blood Institute
2024-2025
Guangxi University
2024-2025
Guangxi Center for Disease Prevention and Control
2025
Capital Medical University
2015-2024
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2024
Guangdong Testing Institute for Product Quality Supervision
2019-2024
Altos Labs
2023-2024
National Animal Husbandry Service
2024
To describe the prevalence of biochemical B(12) deficiency in adults with type 2 diabetes taking metformin compared those not and without diabetes, explore whether this relationship is modified by vitamin supplements.Analysis data on U.S. ≥50 years age (n = 1,621) or 6,867) from National Health Nutrition Examination Survey (NHANES), 1999-2006. Type was defined as clinical diagnosis after 30 initiation insulin therapy within 1 year. Those were classified according to their current use....
For women of reproductive age, a population-level red blood cell (RBC) folate concentration below the threshold 906 nmol/L or 400 ng/mL indicates insufficiency and suboptimal neural tube defect (NTD) prevention. A corresponding population plasma/serum for optimal NTD prevention has not been established.The aim this study was to examine association between plasma RBC concentrations estimated (pf-IT) (RBCf-IT) nmol/L.We analyzed data on age (n = 1673) who participated in population-based,...
Red blood cell (RBC) folate concentrations are a potential biomarker of folate-sensitive neural tube defect (NTD) risk in the population. The purpose this analysis was to describe women U.S. population with RBC below those associated optimal NTD prevention.We used data from 2007 2012 National Health and Nutrition Examination Survey (NHANES) assess status childbearing age relative categories for based on concentrations. We defined suboptimal as prevalence ≥9 NTDs per 10,000 live births.Among...
The US CDC and the Institute of Medicine recommend that women capable becoming pregnant consume ≥400 µg synthetic folic acid/d to prevent neural tube defects (NTDs). United States has 3 sources acid: fortified enriched cereal grain products (ECGPs), ready-to-eat (RTE) cereals, dietary supplements.Our objectives were as follows: 1) estimate usual daily acid intake distributions red blood cell (RBC) folate concentrations among consuming from different sources; 2) assess total associated with...
Despite the increase in global prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD), no approved drug currently exists for disease. Poria cocos (Schw.) Wolf (P. cocos) is a medicinal mushroom belonging to family polyporaceae widely used TCM clinics protect and treat obesity. However, its efficacy, practical components, underlying mechanism against MAFLD are yet be determined. In this study, we evaluated effects ethanol extract (EPC) on hepatic dyslipidemia, steatosis,...
Abstract BACKGROUND Maternal nutritional status has been evaluated to clarify its role in development of neural tube defects (NTDs). folate intake during pregnancy closely for association with NTDs. The study objective was examine associations between NTDs and other dietary periconceptional micronutrient intake, particularly nutrients involved one‐carbon metabolism or antioxidant activity. METHODS Using data from the National Birth Defects Prevention Study, 1997–2005, logistic regression...
Cognitive health is a public concern among older adults. Dietary supplement (SUP) use common and concerns have been raised about high folic acid intake those with vitamin B-12 deficiency exacerbation of poor cognitive performance (PCP). We evaluated SUP use, usual intake, blood folate concentrations in relation to performance. used NHANES 2011–2014 data on adults aged ≥60 y (n = 2867) estimated total from diet supplements, SUPs, folates, concentrations, insufficiency (≤258 pmol/L), (serum...
Abstract Background Gestational diabetes mellitus (GDM) and excessive body weight are two key risk factors for adverse perinatal outcomes. However, it is not clear whether restricted gestational gain (GWG) favorable to reduce the pregnancy neonatal outcomes in women with GDM. Therefore, this study aimed assess association of GWG after an oral glucose tolerance test maternal Methods This prospective cohort assessed (OGTT) 3126 GDM, adjusted age, pre-pregnancy mass index, height, gravidity,...
Abstract Several studies have indicated that interrupted epigenetic reprogramming using Yamanaka transcription factors (OSKM) can rejuvenate cells from old laboratory animals and humans. However, the potential of OSKM-induced rejuvenation in brain tissue has been less explored. Here, we aimed to restore cognitive performance 25.3-month-old female Sprague–Dawley rats OSKM gene therapy for 39 days. Their progress was then compared with untreated 3.5-month-old as well control treated a placebo...
Long-term hematopoietic output is dependent on stem cell (HSC) homeostasis which maintained by a complex molecular network. Among these, microRNAs play crucial roles, while the underlying basis has not been fully elucidated. Here, we show that miR-21 enriched in murine HSCs, and mice with conditional knockout of exhibit an obvious perturbation normal hematopoiesis. Moreover, significant loss HSC quiescence long-term reconstituting ability are observed absence miR-21. Further studies reveal...
Women of reproductive age (WRA) are a high-risk population for anemia and micronutrient deficiencies. However, there few representative population-level data from India, which could help inform evidence-based recommendations policy.